A5073051682- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Intracranial Aneurysms: Treatment and Complications
- Meningioma and schwannoma management
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Musculoskeletal pain and rehabilitation
- Moyamoya disease diagnosis and treatment
- Cervical and Thoracic Myelopathy
- Head and Neck Surgical Oncology
- Medical Imaging and Analysis
- Cerebrospinal fluid and hydrocephalus
- Neurofibromatosis and Schwannoma Cases
- Scoliosis diagnosis and treatment
- Management of metastatic bone disease
- Vascular Malformations Diagnosis and Treatment
- Surgical site infection prevention
- Neurological disorders and treatments
- Opioid Use Disorder Treatment
- Neurosurgical Procedures and Complications
- Neurogenesis and neuroplasticity mechanisms
- Clinical practice guidelines implementation
- Nicotinic Acetylcholine Receptors Study
- Cardiac, Anesthesia and Surgical Outcomes
Stanford University
2005-2022
Harvard University
2010-2021
University Hospital of Zurich
2021
University of Zurich
2021
Copyright Licensing Agency
2021
Stanford Medicine
2005-2020
Center for Global Health
2020
Stanford Health Care
2014-2020
W.K. Kellogg Foundation
2020
University of Michigan
2020
Low back pain (LBP) with or without lower extremity (LEP) is one of the most common reasons for seeking medical care. Previous studies investigating costs in this population targeted patients receiving surgery. Little known about health care utilization among who do not undergo surgery.To assess use resources LBP and LEP management analyze associated costs.This cohort study used a retrospective analysis commercial database containing inpatient outpatient data more than 75 million...
Object Management of unruptured intracranial aneurysms remains controversial in neurosurgery. The contribution morphological parameters has not been included the treatment paradigm a systematic manner or for any particular aneurysm location. authors present large sample middle cerebral artery (MCA) that were assessed using variables to determine associated with rupture. Methods Preoperative CT angiography (CTA) studies evaluated Slicer software generate 3D models and their surrounding...
An immature state of cellular differentiation—characterized by stem cell–like tendencies and impaired differentiation—is a hallmark cancer. Using glioblastoma multiforme (GBM) as model system, we sought to determine whether molecular determinants that drive cells toward terminal differentiation are also genetically targeted in carcinogenesis neutralizing such genes plays an active role reinforce the promote malignancy. To end, screened 71 with known roles promoting nervous system development...
Abstract BACKGROUND Outpatient anterior cervical discectomy and fusion (ACDF) is a promising candidate for US healthcare cost reduction as several studies have demonstrated that overall complications are relatively low early discharge can preserve high patient satisfaction, morbidity, minimal readmission. OBJECTIVE To compare clinical outcomes associated costs between inpatient ambulatory setting ACDF. METHODS Demographics, comorbidities, emergency department (ED) visits, readmissions,...
Abstract Patient-reported outcome measures (PROMs) are commonly used to estimate disability of patients with spinal degenerative disease. Emerging technological advances present an opportunity provide objective measurements activity. In a prospective, observational study we utilized low-cost consumer grade wearable accelerometer (LCA) determine patient activity (steps per day) preoperatively (baseline) and up one year (Y1) after cervical lumbar spine surgery. We studied 30 (46.7% male; mean...
In contrast to size, the association of morphological characteristics intracranial aneurysms with rupture has not been established in a systematic manner. We present an analysis variables that are associated anterior communicating artery determine site-specific risk variables. One hundred and twenty-four were treated single institution from 2005 2010, CT angiograms (CTAs) or rotational angiography 79 patients (42 ruptured, 37 unruptured) analyzed. Vascular imaging was evaluated 3D Slicer©...
BACKGROUND: Smoking is a well-known independent risk factor for both aneurysm formation and rupture. There mounting evidence that morphology beyond size can have significant role in rupture by its effects on aneurysmal hemodynamics. OBJECTIVE: To study the variation between smokers nonsmokers delineate how changes these factors might affect METHODS: We generated 3-dimensional models of aneurysms their surrounding vasculature analyzing preoperative computed tomography angiograms with Slicer...
The pathogenesis of intracranial aneurysms is multifactorial and includes genetic, environmental, anatomic influences. Hemodynamic stress plays a particular role in the formation aneurysms, which conditioned by geometry morphology vessel trees.To identify image-based morphological parameters that correlated with basilar artery tip (BTAs) location-specific manner.Morphological obtained from computed tomographic angiographies 33 patients BTAs at other locations were evaluated Slicer, an...
Intrawound vancomycin powder has been studied extensively in spinal fusion surgeries and found to reduce rates of surgical site infections (SSIs) significantly. Despite its success surgeries, topical not with respect cranial neurosurgery.To evaluate the efficacy intrawound for prevention SSIs following open craniotomies.We retrospectively analyzed a large series 350 patients from 2011 2015 pre/postintervention study use postoperative craniotomy infection rates. We had preintervention control...
Objective functional measures such as the 6-minute walking test (6WT) are increasingly applied to evaluate patients with degenerative diseases of lumbar spine before and after (surgical) treatment. However, traditional 6WT is cumbersome apply, it requires specialized in-hospital infrastructure personnel. The authors set out compare distance (6WD) measurements obtained a newly developed smartphone application (app) those gold-standard wheel (DW).
Abstract BACKGROUND Modern robotic-assist surgical systems have revolutionized stereotaxy for a variety of procedures by increasing operative efficiency while preserving and even improving accuracy safety. However, experience with robotic in deep brain stimulation (DBS) surgery is scarce. OBJECTIVE To present an initial series DBS performed utilizing frameless solution image-guided stereotaxy, report on efficiency, stereotactic accuracy, complications. METHODS This study included the 20...