A5072486361- Intraocular Surgery and Lenses
- Multiple Myeloma Research and Treatments
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Liver Disease Diagnosis and Treatment
- Peptidase Inhibition and Analysis
- Protein Degradation and Inhibitors
- Cancer Mechanisms and Therapy
- Retinal Diseases and Treatments
- Liver Disease and Transplantation
- Circular RNAs in diseases
- Folate and B Vitamins Research
- Plant-based Medicinal Research
- Cardiovascular Health and Risk Factors
- Retinal Imaging and Analysis
- Organ Transplantation Techniques and Outcomes
- Retinopathy of Prematurity Studies
- Oral microbiology and periodontitis research
- Complement system in diseases
- Cardiovascular Health and Disease Prevention
- Spaceflight effects on biology
- Dental Radiography and Imaging
- Liver Diseases and Immunity
- Endodontics and Root Canal Treatments
- Optical Imaging and Spectroscopy Techniques
Huashan Hospital
2025
Fudan University
2025
Ministry of Industry and Information Technology
2025
Beihang University
2025
Wuxi People's Hospital
2019-2024
Nanjing Medical University
2019-2024
Lanzhou University
2023
Jiangyin People's Hospital
2020
Weatherford College
2019
<title>Abstract</title> Background Despite increased use, the impact of elder donors on outcomes liver transplantation remains controversial, particularly with regard to postoperative complications. Methods Retrospective data adult deceased between August 1, 2017 November 30, 2023 were collected. The aim was compare survival as well complications recipients elderly (≥ 60 years) younger (< years). Results Out a total 950 transplants, 201 and 749 donors. No difference in overall or...
Diabetic retinopathy (DR) is a common complication in patients with diabetes, and proliferative DR (PDR) has become an important cause of blindness; however, the mechanisms involved have not been fully elucidated. miRNAs long noncoding RNAs can play role DR, they accurately regulate expression target genes through new regulatory model: competing endogenous RNAs. We isolated total RNA extracellular vesicles (EVs) serum healthy individuals diabetes without non-PDR, or PDR, performed deep...
To explore the prognostic value of Mayo Additive Staging System (MASS) in real-world patients with newly diagnosed multiple myeloma(MM).The clinical data 307 MM from August 2015 to June 2022 were retrospectively analyzed. Survival analysis was conducted for each subgroup according MASS. The MASS compared original staging systems evaluate its value. Patients high-risk group further stratified.Patients divided into stages I (93 cases), II (91 and III (123 differences overall survival (OS)...
To explore the prognostic factors of patients with multiple myeloma (MM) based on nutritional status.The Controlling Nutritional Status (CONUT) score and clinical parameters at diagnosis 203 newly diagnosed MM hospitalized in department hematology, Wuxi People's Hospital from January 1, 2007 to June 30, 2019 were analyzed retrospectively. The best cut-off value was determined by ROC curve, divided into high CONUT group (>6.5 points) low (≤6.5 points); through COX regression multivariate...
Berberine, a traditional Chinese medicine, is an isoquinoline alkaloid extracted from the rhizome of Coptis chinensis. It has anti-inflammatory and antidiarrheal effects commonly used in treatment infections gastrointestinal diseases. In recent years, studies have found that berberine can play wide range anti-cancer leukemia, lymphoma, multiple myeloma, etc. hematologic malignancies, induce autophagy, promote apoptosis, regulate cell cycle, inhibit inflammatory response, cause oxidative...
Abstract Background Better understanding of the danger zone anatomy in mesial roots (MRs) mandibular first molars (MFMs) may serve to decrease risk mishaps. This study aimed measure minimal distal dentine thicknesses MRs MFMs a native Chinese population using cone-beam computed tomography (CBCT). Methods CBCT images 1792 from 898 patients were analyzed. The mesiobuccal (MB) and mesiolingual (ML) canals below furcation 1, 2, 3, 4, 5 mm measured. association between root lengths, patient’s age...
Objective To evaluate the efficacy and outcome of 25 gouge (25G) minimally invasive vitrectomy combined with cataract extraction trabeculectomy surgeries for malignant glaucoma. Methods Retrospective cohort study was performed.Clinical data 19 glaucoma patients (19 eyes) who received 25G from January 2012 to 2017 in Wuxi People's Hospital were reviewed retrospectively.The operative methods selected according predisposing cause.25G posterior capsulotomy performed on eyes after...
Objective To evaluate the clinical efficacy of Volk gonioscope in phacoemulsification combined with goniosynechialysis. Methods Five hundreds and fifty-eight eyes 440 patients primary angle-closure glaucoma cataract underwent operation combind goniosynechialysis under our hospital. The vision, intraocular pressure(IOP), angle anterior chamber, depths central chamber complications were observed before after surgery. Results The visual acuity was improved compared that surgery...
Objective To evaluate the effect of lensectomy and anterior vitrectomy with 23-gauge transconjunctival system for pediatric cataract. Methods Seventy-one eyes 71 cases cataract in our hospital from January 2009 to December 2013 were retrospectively studied. The age range was 0.5 2.0 years old all randomly divided into two groups: group A(control group) received posterior continuous curvilinear capsularhexis combined vitrectomy; performed B(observation group). visual acuity, capsular...
Objective: Considering that type 2 diabetes mellitus (T2DM) may be one of the strongest risk factors for promoting nonalcoholic steatosis to advanced fibrosis, we aimed investigate prevalence and identify associated with compensated chronic liver diseases (cACLD) among Chinese adults T2DM in community. Methods: This is a prospective large-scale study covering six cities China. We enrolled patients registered community between June 2021 November 2022, collected baseline demographics...
Background and Purpose: The ongoing chronic fibrosis hypertrophy of ligamentum flavum (LF) is an important cause lumbar spinal canal stenosis (LSCS). Our previous work showed that WNT1 inducible signaling pathway protein 1 (WISP-1) a critical driver LF fibrosis. This study was designed to explore the mechanism by which WISP-1 activated its underlying mechanisms in Experimental Approach: We studied expression Hedgehog-related proteins human tissues. Cell viability, cell cycle, apoptosis rate...
Abstract Background : Recently, two prognostic evaluation systems based on different angles, UK Myeloma Research Alliance proposed Risk Profile(MRP) and chinese inflammatory scoring index(IPSI), have shown differences in newly diagnosed multiple myeloma(MM) patients without transplantation. However, there is no relevant research whether a difference the of systems. Methods The study used these to evaluate prognosis 160 with MM bortezomib transplantation from January 2007 June 2018. Results...