A5100745851- Hydrogen embrittlement and corrosion behaviors in metals
- Corrosion Behavior and Inhibition
- Lymphoma Diagnosis and Treatment
- Aluminum Alloys Composites Properties
- Nanoparticle-Based Drug Delivery
- Microstructure and Mechanical Properties of Steels
- Chronic Lymphocytic Leukemia Research
- Advanced biosensing and bioanalysis techniques
- Microstructure and mechanical properties
- Material Properties and Failure Mechanisms
- PI3K/AKT/mTOR signaling in cancer
- Welding Techniques and Residual Stresses
- Electrocatalysts for Energy Conversion
- CAR-T cell therapy research
- Intermetallics and Advanced Alloy Properties
- Cancer-related gene regulation
- Metal and Thin Film Mechanics
- Ubiquitin and proteasome pathways
- Advanced battery technologies research
- CNS Lymphoma Diagnosis and Treatment
- Electromagnetic wave absorption materials
- Metallurgy and Material Forming
- Nuclear Materials and Properties
- Nanoplatforms for cancer theranostics
- Force Microscopy Techniques and Applications
Mianyang Third People's Hospital
2025
Shenyang Pharmaceutical University
2021-2024
University of Miami
2016-2024
Sylvester Comprehensive Cancer Center
2016-2024
Zhengzhou University
2022-2024
University of Chinese Academy of Sciences
2016-2024
Huawei Technologies (China)
2023-2024
NARI Group (China)
2024
Lanzhou Institute of Chemical Physics
2016-2024
Chinese Academy of Sciences
2016-2024
Statins have shown promise as anticancer agents in experimental and epidemiologic research. However, any benefit that they provide is likely context-dependent, for example, applicable only to certain cancers or combination with specific drugs. We report inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) using statins enhances the proapoptotic activity B cell lymphoma-2 (BCL2) inhibitor venetoclax (ABT-199) primary leukemia lymphoma cells but not normal human peripheral...
Abstract Preimplantation genetic screening (PGS) detects chromosomal aneuploidy from DNA extracted trophectodermal biopsy of the embryos before implantation. Although a controlled study showed no difference in pregnancy rates between this invasive cell technique and non-biopsied control group, potential long-term damage by current PGS method has not be completely ruled out. We therefore tested less-invasive protocol which utilizes spent culture medium combining with blastocoel fluid (ECB) to...
Objective To investigate the effectiveness and safety of non-invasive high-frequency oscillatory ventilation (NHFOV) in post-extubation preterm infants. Methods This was a randomized, controlled trial. A total 149 infants aged between 25 to 34 weeks’ gestational age with birth weight <1500 g who required invasive mechanical on admission were included. After extubation, they randomized NHFOV group (n = 47), nasal intermittent positive pressure (NIPPV) 51), or continuous airway (NCPAP) 51)....
A new lambda-cyhalothrin/castor oil-based polyurethane formulation with controlled-release behavior and good foliage adhesion properties is prepared.
Abstract Purpose: The DEAD-box RNA helicase eIF4A1 carries out the key enzymatic step of cap-dependent translation initiation and is a well-established target for cancer therapy, but no drug against it has entered evaluation in patients. We identified characterized natural compound with broad antitumor activities that emerged from first target-based screen to identify novel inhibitors. Experimental Design: tested potency specificity marine elatol versus ATPase activity. also assessed...
Abstract Solar‐driven interfacial evaporation (SIE) is very promising to solve the issue of fresh water shortage, however, poor salt resistance severely hinders long‐term stable SIE and collection. Here, we report design superhydrophilic solar evaporators for desalination, collection by vertical deposition. The are prepared sequentially deposition silicone nanofilaments, polypyrrole Au nanoparticles on a polyester fabric composed microfibers. feature excellent photothermal effect ultrafast...
Mitoxantrone (MTO) is an anthraquinone antitumor drug with potent therapeutic benefits. However, its clinical application restricted by the severe side effects stemming from poor tumor selectivity. In this study, MTO and cholesterol (CLS) were conjugated via a tumor-selective disulfide bond to obtain MTO-SS-CLS prodrug. Interestingly, could self-assemble into uniform nanoassemblies, addition of DSPE-PEG2K significantly improved self-assembly behavior stability. Moreover, compared solutions,...
Rationale: Small-molecule prodrug nanoassembly is emerging as an efficient platform for chemotherapy.The self-assembly stability plays a vital role on the drug delivery efficiency of nanoassembly.It reported that fluoroalkylation could improve amphiphilic polymers by utilizing unique fluorination effect.But application small-molecule has never been reported.Methods: Here, fluoro-modified was developed conjugating paclitaxel with perfluorooctanol (F8-SS-PTX), and paclitaxel-octanol...
Few-shot image generation is a challenging task since it aims to generate diverse new images for an unseen category with only few images. Existing methods suffer from the trade-off between quality and diversity of generated To tackle this problem, we propose Hyperbolic Attribute Editing (HAE), simple yet effective method. Unlike other that work in Euclidean space, HAE captures hierarchy among using data seen categories hyperbolic space. Given well-trained HAE, can be by moving latent code...
Metaplastic carcinoma of the breast is an extremely rare and highly aggressive malignancy associated with a poor prognosis. Breast spindle cell subtype metaplastic carcinoma. We present case 48-year-old woman who was found to have nodule during routine examination two years ago. Pathological following surgical resection confirmed diagnosis One year later, follow-up CT scan detected progressively enlarging mass in left lower lobe lung, which histologically as metastatic after excision....