A5101549190- Neonatal Respiratory Health Research
- Genomics, phytochemicals, and oxidative stress
- Neonatal and fetal brain pathology
- Diet and metabolism studies
- Neuroscience and Neuropharmacology Research
- Congenital Diaphragmatic Hernia Studies
- Liver Disease Diagnosis and Treatment
- Plant tissue culture and regeneration
- Liver Disease and Transplantation
- Congenital Heart Disease Studies
- Anesthesia and Neurotoxicity Research
- Neuroscience of respiration and sleep
- Traumatic Brain Injury and Neurovascular Disturbances
- RNA Interference and Gene Delivery
- Bone Metabolism and Diseases
- Inflammatory mediators and NSAID effects
- Drug Transport and Resistance Mechanisms
- Cardiac Valve Diseases and Treatments
- Radiopharmaceutical Chemistry and Applications
- Plant-Microbe Interactions and Immunity
- Urinary Bladder and Prostate Research
- Gestational Diabetes Research and Management
- Monoclonal and Polyclonal Antibodies Research
- Adipose Tissue and Metabolism
- Infant Development and Preterm Care
National Clinical Research Center for Digestive Diseases
2017-2025
Air Force Medical University
2014-2025
Xijing Hospital
2014-2025
Zhejiang Chinese Medical University
2021-2025
Third Hospital of Changsha
2024-2025
Northeast Forestry University
2010-2024
Hunan Agricultural University
2024
Zhejiang Provincial People's Hospital
2024
Shanghai First Maternity and Infant Hospital
2024
Hangzhou Medical College
2024
Objective Limited data are available on the prevention of variceal rebleeding in cirrhotic patients with portal vein thrombosis (PVT). This study aimed to compare transjugular intrahepatic portosystemic shunt (TIPS) covered stents versus endoscopic band ligation (EBL) plus propranolol for among cirrhosis and PVT. Design Consecutive (94% Child-Pugh class A or B) PVT who had bleeding past 6 weeks were randomly assigned TIPS group (n=24) EBL (EBL+drug, n=25), respectively. Primary endpoint was...
Obesity is becoming a major global health problem in children that can cause diseases such as type 2 diabetes and metabolic disorders, which are closely related to the gut microbiota. However, underlying mechanism remains unclear. In this study, significant positive correlation was observed between Prevotella copri (P. copri) obesity (p = 0.003). Next, effect of P. on explored by using fecal microbiota transplantation (FMT) experiment. Transplantation copri. increased serum levels fasting...
Dehydration-responsive element binding factors (DREBs) play important roles in plant growth, development, and stress signaling pathways model plants. However, little is known about the function of DREBs apple (Malus × domestica), a widely cultivated crop that frequently threatened by drought. We isolated DREB gene from Malus sieversii (Ledeb.) Roem., MsDREB6.2, investigated its functions using overexpression analysis chimeric repressor gene-silencing technology (CRES-T). identified possible...
Abstract We evaluated several doses of cis‐4‐(phosphonomethyl)‐2‐piperidine‐carboxylic acid (CGS‐19755), a potent competitive N ‐methyl‐D‐aspartate (NMDA) receptor antagonist, systemically administered either before or after 20 to 30 minutes global ischemia in rats. measured outcome by mortality, histological damage light microscopy, and learning ability on an eight‐arm maze, determined the drug's mechanism action immunohistochemical assay calcium‐calmodulin binding. High‐dose treatment...
Cyanidin-3-glucoside (C3G) has been demonstrated to have hepatoprotective effect for oxidative stress-related liver damage due its antioxidant activity. However, the mechanisms of C3G are not fully understood. In this study, was evaluated and underlying molecular were investigated in vivo vitro. attenuated H2O2 induced cell apoptosis through ROS scavenging enhancing defence system The AMPK/Nrf-2 signal pathway is involved mechanism protective C3G. addition, vivo. alleviated CCl4-induced mice...
Objective To investigate the effectiveness and safety of non-invasive high-frequency oscillatory ventilation (NHFOV) in post-extubation preterm infants. Methods This was a randomized, controlled trial. A total 149 infants aged between 25 to 34 weeks’ gestational age with birth weight <1500 g who required invasive mechanical on admission were included. After extubation, they randomized NHFOV group (n = 47), nasal intermittent positive pressure (NIPPV) 51), or continuous airway (NCPAP) 51)....
Corilagin is a member of polyphenolic tannins. Its antimicrobial activity and action mechanism against Escherichia coli, Staphylococcus aureus Candida albicans were investigated through membrane permeability. Crystal violet staining determination, outer (OM) inner (IM) permeability, sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) atomic force microscopy (AFM) used as methods for our investigation. The minimum inhibitory concentrations 62.5, 31.25 62.5 µg/mL E. S. C....
It is well known that tumor microenvironment plays a vital role in drug resistance and cell adhesion-mediated (CAM-DR), form of de novo resistance. In our previous study, we reported MGr1-Ag/37LRP ligation-induced adhesion participated protecting gastric cancer cells from number apoptotic stimuli caused by chemotherapeutic drugs. Further study suggested MGr1-Ag could prompt CAM-DR through interaction with laminin. However, the MGr1-Ag-initiated intracellular signal transduction pathway still...