A5030610789- Process Optimization and Integration
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Algorithms and Applications
- Granular flow and fluidized beds
- Inflammatory Myopathies and Dermatomyositis
- Crystallization and Solubility Studies
- Air Quality and Health Impacts
- Advanced Sensor and Control Systems
- Cyclone Separators and Fluid Dynamics
- Atmospheric chemistry and aerosols
- Embedded Systems and FPGA Design
- Analytical Chemistry and Chromatography
- Fluid Dynamics and Mixing
- Systemic Lupus Erythematosus Research
- Toxic Organic Pollutants Impact
- Cancer-related molecular mechanisms research
- Mosquito-borne diseases and control
- Cancer, Stress, Anesthesia, and Immune Response
- Environmental Impact and Sustainability
- Freezing and Crystallization Processes
- Atherosclerosis and Cardiovascular Diseases
- Carbon dioxide utilization in catalysis
- Heterotopic Ossification and Related Conditions
- Diet, Metabolism, and Disease
- Industrial Gas Emission Control
Qingdao University of Science and Technology
2007-2025
China Medical University
2013-2025
China Pharmaceutical University
2019-2024
Zhengzhou Children's Hospital
2023-2024
Capital Medical University
2013-2024
Beijing Children’s Hospital
2013-2024
Zhengzhou University
2023-2024
Zhongyuan University of Technology
2024
Southwest University
2024
Huazhong Agricultural University
2024
Post-stroke cognitive impairment (PSCI) is a common neuropsychiatric complication of stroke. Mounting evidence has demonstrated connection between gut microbiota (GM) and disease. Our previous study revealed the changes in GM mouse model vascular dementia. However, characteristic PSCI remains unclear. This aimed to characterize explored potential as biomarkers. A total 93 patients with ischemic stroke were enrolled this study. The divided into two groups according their MoCA scores 3 months...
Objective To construct a predictive tool for the efficacy of intravenous immunoglobulin (IVIG) therapy in children with Kawasaki disease (KD) Beijing, China. Design This was cohort study. Data set (including clinical profiles and laboratory findings) KD diagnosed between 1 January 2010 31 December 2015 used to analyse risk factors scoring system. 2016 validate this model. Setting Children’s Hospital Capital Institute Pediatrics Beijing Hospital. Patients 2102 KD. Interventions No. Main...
Cassia mimosoides Linn (CMD) is a traditional Chinese herb that clears liver heat and dampness. It has been widely administered in clinical practice to treat jaundice associated with damp-heat pathogen obesity. Emodin (EMO) major bioactive constituent of CMD apparent therapeutic efficacy against obesity fatty liver. Here, we investigated the protective effects underlying mechanisms EMO high-fat diet (HFD)-induced nonalcoholic disease (NAFLD).We aimed investigate whether activates farnesoid X...
Abstract Increased tissue stiffness is a hallmark of cancer and promotes tumor progression. It hypothesized that decreased tumorous stress may aid or sensitize chemotherapies. To overcome extracellular matrix (ECM) stiffening fulfill sensitized chemotherapy in one nanosystem, reactive oxygen species‐activatable nanoenzyme (SP‐NE) based on dendritic polyglycerol scaffold, integrating collagenase paclitaxel (PTX) prodrug, constructed. The dense tough ECM highly remitted by SP‐NE the...
Floated pH-degradable PVA nanogels (FA-NGs) are developed for simultaneous delivery of DTX and IDO1-inhibitor N9 to enhance cancer chemo-immunotherapy.
Gas-phase hydrogen/deuterium (H/D) exchange was used to probe the conformations, gas-phase acidities, and sites of deprotonation isomeric flavonoid aglycons glycosides. The flavonoids in each isomer series were differentiated on basis their relative rate constants total numbers exchanges. For example, that possess neohesperidose-type disaccharides may undergo faster far more extensive than rutinoside flavonoids. structural factors promote or prevent H/D identified correlated with...
Sodium salicylate can be formed by carboxylation of solid sodium phenol particles with carbon dioxide gas under certain conditions. Single-factor experiments were carried out self-made dried in a batch high-pressure reactor. It was determined that the reaction more suitable conditions temperature 160 °C, pressure 0.55 MPa, time about 40 min, and stirring speed 50 rpm. Besides that, water content material also had important effects on yield. Through establishment kinetic model between gas,...
The relative threshold dissociation energies of a series flavonoid/transition metal/auxiliary ligand complexes the type [MII (flavonoid − H) auxiliary ligand]+ formed by electrospray ionization (ESI) were measured energy-variable collisionally activated (CAD) in quadrupole ion trap (QIT). For each isomeric flavonoid diglycoside pairs, rutinoside (with 1–6 inter-saccharide linkage) requires greater CAD energy and thus has higher than its neohesperidoside 1–2 isomer. Likewise, containing...
Sensitive and precise analytical methods are needed for flavonols, a subclass of flavonoids that has strong antioxidant activity. We report an improved method identifying the predominant quercetin kaempferol, by collisionally activated dissociation (CAD) quantifying them high-performance liquid chromatography electrospray ionization mass spectrometry (HPLC-ESI-MS) in selected ion monitoring mode. Practical applications were demonstrated using several kale biological samples. Two commercial...
Illustration of pH-degradable microgels (MGs) for the simultaneous encapsulation OA and JQ1 an enhanced oncolytic viral treatment with JQ1-meidated boosting replication PD-L1 suppression.
Adenoid hypertrophy (AH) is a common pediatric disease caused by inflammatory stimulation. The pro-inflammatory cytokine IL-32 has been reported to promote airway inflammation and also be involved in the pyroptosis pathway. However, whether can contribute AH mediating remains elucidated. present study aimed investigate role of determine potential underlying mechanisms. tissues were collected from healthy children with AH, expression IL-32, NACHT LRR PYD domains-containing protein 3 (NLRP3)...
Leukemia inhibitory factor (LIF) is a neuroprotective cytokine that necessary for the normal development of astrocytes. Oxygen-glucose deprivation (OGD) can induce astrocyte proliferation by increasing hypoxia-inducible alpha (HIF-1alpha) and vascular endothelial growth (VEGF). Here, we studied whether LIF affects cultured primary rat astrocytes under OGD conditions measuring EdU incorporation into DNA expression proliferating cell nuclear antigen (PCNA) mRNA protein. Our findings show low...