О. А. Денисова

ORCID: 0000-0003-1652-9622
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About
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Research Areas
  • Sarcoidosis and Beryllium Toxicity Research
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Healthcare Systems and Public Health
  • Gastroesophageal reflux and treatments
  • Sinusitis and nasal conditions
  • Bacillus and Francisella bacterial research
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Occupational exposure and asthma
  • S100 Proteins and Annexins
  • Eosinophilic Esophagitis
  • Trace Elements in Health
  • Nosocomial Infections in ICU
  • Hormonal and reproductive studies
  • Pulmonary Hypertension Research and Treatments
  • Big Data and Business Intelligence
  • Pneumonia and Respiratory Infections
  • Cardiovascular Disease and Adiposity
  • Nasal Surgery and Airway Studies
  • Human Health and Disease
  • Therapeutic Uses of Natural Elements
  • Pediatric health and respiratory diseases
  • Vascular Anomalies and Treatments
  • Discourse Analysis and Cultural Communication
  • Sepsis Diagnosis and Treatment
  • Heavy Metal Exposure and Toxicity

Siberian State Medical University
2010-2025

Ministry of Health of the Russian Federation
2019-2023

Omsk State Medical University
2019

Relevance The relevance of developing a platform for automating interviews using artificial intelligence is determined by number factors. concept this product touches on two important areas: information technology and human resource management. Many industries actively need to replace outdated methods organizing HR processes with innovative solutions intelligence. Secondly, in the course work, study possibilities integrating various machine learning into recruitment touched upon, which has...

10.17122/1999-5458-2025-21-1-130-140 article EN Electrical and data processing facilities and systems 2025-01-01

Aim . Using statistical modeling techniques, we aim to develop a model that optimizes the prediction of severity sarcoidosis affects respiratory system (SRS) based on identification and determination signs (anamnestic, clinical, laboratory, instrumental examination data, etc.) associated with disease subsequent stratification long-term risk for pulmonary hypertension (PH) development. Materials methods The 12-year observational cohort comparative study included 298 participants, both male...

10.20538/1682-0363-2025-1-36-44 article EN cc-by Bulletin of Siberian Medicine 2025-04-14

The article presents data concerning prevalence of sarmidosis in Tomsk and the region for 16 years impacting ecological geochemical factors (elemental composite incrustation snow, soils) on disease. morbidity individuals without undergoing impact occupational hazards is reliably higher areas with increased anthropogenic loading (the Oktiabrskii district Tomsk, rural district, North- Eastern sector, city Seversk, Parabelskii Kolpashevskii districts, Strejevoii). positive associations were...

10.18821/0044-197x-2016-60-3-147-151 article EN Health Care of the Russian Federation 2019-05-24

As a rule, heart damage in patients with sarcoidosis of respiratory organs (SOD) is not diagnosed time, so very important and urgent task to identify common rhythm conduction disorders. The aim the study was investigate main clinical manifestations SOD, depending on peculiarities disease course compare frequency severity pulmonary extrapulmonary sarcoidosis, including myocardial lesions electrocardiographic (ECG) signs Methods . In period 2006– 2016, pilot open prospective uncontrolled...

10.18093/0869-0189-2020-30-2-204-212 article EN cc-by PULMONOLOGIYA 2020-06-21

Irrigation therapy aimed at effective cleansing of the nasal cavity and elimination pathogens allergens is included in standard combined treatment diseases upper respiratory tract accompanied by various forms rhinitis or its symptoms. Isotonic saline solutions used for irrigation moisturize mucosa maintain normal physiological state. Hypertonic reduce swelling turbinates reducing obstruction greatly improve mucociliary clearance as compared to isotonic solutions, but may have a cilitoxic...

10.15690/vsp.v14i5.1441 article EN cc-by Вопросы современной педиатрии 2015-11-17

The review summarizes and analyzes the results of domestic major foreign studies recent years concerning prevalence metabolic syndrome components explanation their role in mechanisms sarcoidosis development. A deep understanding pathogenesis (MS) terms it risk factors for a severe course complications most socially sensitive noncommunicable diseases clustered within MS can underly development effective pathogen-specific approaches to treatment.

10.20538/1682-0363-2023-3-80-87 article EN cc-by Bulletin of Siberian Medicine 2023-10-17

Despite significant progress in the field of prevention, early diagnosis and antibacterial therapy, community-acquired pneumonia still retains status not only most common among acute infectious diseases, but is also a frequent source sepsis, which greatly increases likelihood death this group patients. The purpose study was to perform comparative analysis clinical laboratory parameters assess nature their changes first 48 hours from moment verification sepsis that developed against...

10.20514/2226-6704-2024-14-2-132-143 article EN cc-by The Russian Archives of Internal Medicine 2024-04-06

10.32687/1561-5936-2024-28-3-319-324 article EN Remedium Journal about the Russian market of medicines and medical equipment 2024-07-01

The objective of the study: to study radiological and morphological parallels in respiratory sarcoidosis (RS). Subjects methods . 121 patients with were enrolled study, their ages varied from 21 66 years, they all examined 2007-2019. analysis manifestations was assessed according main parameters (symmetry lesions, size intrathoracic lymph nodes, presence dissemination, pneumofibrosis). extended testing biopsy specimens carried including evaluation quantitative qualitative composition...

10.21292/2075-1230-2021-99-1-48-54 article EN cc-by Tuberculosis and lung diseases 2021-02-02

Sarcoidosis is a systemic disease characterized by the development of chronic immune inflammation and formation granulomas. It important to know clinical, morphological immunologic variants course this in order investigate pathomorphologic parameters granuloma. Of late negative trends have been observed changes sarcoidosis pathomorphology. Due above it predictors for disease, including specific granulematous inflammatory process various clinical not only from point view diagnostics but...

10.21292/2075-1230-2017-95-3-48-54 article EN cc-by Tuberculosis and lung diseases 2017-03-01

The demand of work is connected with prevalence a gastroesophageal reflux disease (GERB) against the background insufficient study age features course this in senior groups. research cohort made 96 patients GERB. All were divided by method randomization into two equal groups quantity: first – persons receiving пантопразол 40 mg/days, second омепразол dose 20 mg/days. Comparative efficiency reception an omeprazol and pantoprazol aspect at GERB from positions assessment indicators quality life...

10.21518/2079-701x-2019-3-55-59 article EN cc-by-nc-nd Meditsinskiy sovet = Medical Council 2019-05-12

Aim . To study clinical and morphological phenotypes in different variants of the course intrathoracic sarcoidosis isolate new phenotypes. Materials methods The included 121 patients with aged 21–66 years (50.4% were men, 49.6% women, average age at time disease onset was 38 years) over period 2007– 2019. During examination, patients’ complaints studied thoroughly, diagnosis histologically verified all cases. an extended histological quantitative qualitative composition biopsy specimens...

10.20538/1682-0363-2021-4-18-24 article EN cc-by Bulletin of Siberian Medicine 2022-01-01

Aim. The aim of the study was to frequency occurrence exposure harmful occupational factors in patients with sarcoidosis respiratory organs, depending on course disease. Materials and methods. An open prospective included 121 system from age 21 66 years, 20072019. diagnosis histologically confirmed all patients. Patients underwent a set laboratory instrumental examinations, studied profane history. presence history contact dangerous production clarified. To determine effect factor...

10.26442/00403660.2021.03.200637 article EN cc-by-nc Terapevticheskii arkhiv 2021-03-15

The purpose of the study was to compare efficacy regular prolonged inhalation therapy with tiotropium bromide delivered via Respimat inhaler and short-acting bronchodilator (SAB) ipratropium bromide/fenoterol in perioperative period patients non-small cell lung cancer (NSCLC) combined chronic obstructive pulmonary disease (copd). Material Methods . included 66 Nsclc copd. received bromide, 5 mcg/day (TB group) or a combination 20/50 mcg/dose, 2 doses 4 times day (SAB for 6 weeks before after...

10.21294/1814-4861-2023-22-5-49-59 article EN cc-by Siberian Journal of Oncology 2023-11-15

Clinical manifestations of sarcoidosis are varied. The reasons have not been completely understood. purpose the study is to explore relationship between morphology granulomas and clinical picture sarcoidosis. <b>Materials:</b> Specimens lungs (n=59) mediastinal lymph nodes (n=15) were obtained during VATS biopsies from patients (radiological stage 1, n=19; 2, n=53 patients; 3, n=2). Morphological included determination formula cellular elements, presence hyalinosis, necrosis, calcification,...

10.1183/1393003.congress-2017.pa3271 article EN 2017-09-01
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