A5025564186- Sarcoidosis and Beryllium Toxicity Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Trace Elements in Health
- Occupational exposure and asthma
- IgG4-Related and Inflammatory Diseases
- Medical Imaging and Pathology Studies
- S100 Proteins and Annexins
- Long-Term Effects of COVID-19
- Respiratory and Cough-Related Research
- Bacillus and Francisella bacterial research
- Research on Leishmaniasis Studies
- Orthopedic Infections and Treatments
- COVID-19 Clinical Research Studies
- Sinusitis and nasal conditions
Krasnoyarsk Regional Clinical Hospital
2019-2025
Siberian State Medical University
2025
The article describes a clinical case of typical course post-COVID interstitial organizing pneumonia, complicated by healthcare-associated infection, in 62-year-old patient without previously confirmed pulmonary pathology.
Aim . Using statistical modeling techniques, we aim to develop a model that optimizes the prediction of severity sarcoidosis affects respiratory system (SRS) based on identification and determination signs (anamnestic, clinical, laboratory, instrumental examination data, etc.) associated with disease subsequent stratification long-term risk for pulmonary hypertension (PH) development. Materials methods The 12-year observational cohort comparative study included 298 participants, both male...
As a rule, heart damage in patients with sarcoidosis of respiratory organs (SOD) is not diagnosed time, so very important and urgent task to identify common rhythm conduction disorders. The aim the study was investigate main clinical manifestations SOD, depending on peculiarities disease course compare frequency severity pulmonary extrapulmonary sarcoidosis, including myocardial lesions electrocardiographic (ECG) signs Methods . In period 2006– 2016, pilot open prospective uncontrolled...
The objective of the study: to study radiological and morphological parallels in respiratory sarcoidosis (RS). Subjects methods . 121 patients with were enrolled study, their ages varied from 21 66 years, they all examined 2007-2019. analysis manifestations was assessed according main parameters (symmetry lesions, size intrathoracic lymph nodes, presence dissemination, pneumofibrosis). extended testing biopsy specimens carried including evaluation quantitative qualitative composition...
Sarcoidosis is a systemic disease characterized by the development of chronic immune inflammation and formation granulomas. It important to know clinical, morphological immunologic variants course this in order investigate pathomorphologic parameters granuloma. Of late negative trends have been observed changes sarcoidosis pathomorphology. Due above it predictors for disease, including specific granulematous inflammatory process various clinical not only from point view diagnostics but...
Aim . To study clinical and morphological phenotypes in different variants of the course intrathoracic sarcoidosis isolate new phenotypes. Materials methods The included 121 patients with aged 21–66 years (50.4% were men, 49.6% women, average age at time disease onset was 38 years) over period 2007– 2019. During examination, patients’ complaints studied thoroughly, diagnosis histologically verified all cases. an extended histological quantitative qualitative composition biopsy specimens...
Aim. The aim of the study was to frequency occurrence exposure harmful occupational factors in patients with sarcoidosis respiratory organs, depending on course disease. Materials and methods. An open prospective included 121 system from age 21 66 years, 20072019. diagnosis histologically confirmed all patients. Patients underwent a set laboratory instrumental examinations, studied profane history. presence history contact dangerous production clarified. To determine effect factor...
The objective of this study was to investigate the relationship between polymorphisms PACRG gene (rs10945890) and CD80 (rs1880661) with susceptibility, course, outcome sarcoidosis. involved 142 sarcoidosis patients 150 healthy individuals from Siberian region Russia. Over 200 clinical features were analyzed at disease onset, followed up for least seven years. PCR-RFLP utilized genotyping, statistical analysis performed using X2 test, Fisher's exact logistic regression after adjusting age sex...
Clinical manifestations of sarcoidosis are varied. The reasons have not been completely understood. purpose the study is to explore relationship between morphology granulomas and clinical picture sarcoidosis. <b>Materials:</b> Specimens lungs (n=59) mediastinal lymph nodes (n=15) were obtained during VATS biopsies from patients (radiological stage 1, n=19; 2, n=53 patients; 3, n=2). Morphological included determination formula cellular elements, presence hyalinosis, necrosis, calcification,...
Sarcoidosis may show a different course from spontaneous regression to chronic recurrent forms. The search for prognosis criteria remains relevant the disease. aim was study relationship between granuloma morphology and clinical of sarcoidosis. Materials: A morphological lungs obtained during VATS biopsies performed in 121 patients with sarcoidosis onset. It included formula cellular elements, number granulomas, giant multinucleated cells, presence hyalinosis, necrosis, calcification,...