A5101812461- Cancer-related molecular mechanisms research
- Nanoplatforms for cancer theranostics
- RNA modifications and cancer
- Glioma Diagnosis and Treatment
- Autophagy in Disease and Therapy
- RNA Research and Splicing
- Circular RNAs in diseases
- MicroRNA in disease regulation
- Hydraulic Fracturing and Reservoir Analysis
- Trigeminal Neuralgia and Treatments
- Mycobacterium research and diagnosis
- Epigenetics and DNA Methylation
- Cancer Immunotherapy and Biomarkers
- Sulfur Compounds in Biology
- Drilling and Well Engineering
- Facial Nerve Paralysis Treatment and Research
- Metal-Organic Frameworks: Synthesis and Applications
- Sexual function and dysfunction studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Medicinal Plant Pharmacodynamics Research
- Ferroptosis and cancer prognosis
- Molecular Sensors and Ion Detection
- Advanced Nanomaterials in Catalysis
- Cancer-related gene regulation
- Radiomics and Machine Learning in Medical Imaging
Pudong Medical Center
2020-2025
Fudan University
2020-2025
Anhui Medical University
2013-2025
Second Hospital of Anhui Medical University
2013-2025
China University of Petroleum, East China
2024
Hainan 301 Hospital
2023
Wenzhou Medical University
2023
Abstract Enhancing the efficacy of glioma treatment poses a significant challenge. Ferroelectric nanomaterials, renowned for their remarkable piezoelectric properties, generate reactive oxygen species (ROS) when exposed to external stimuli or specific environmental conditions. This characteristic positions them as promising platforms highly effective cancer therapies. In this study, two‐dimensional (2D) black Bi 4 Ti 3 O 12 ferroelectric perovskite nanocatalysts with engineered vacancies are...
Abstract LncRNAs play a pivotal role in tumorigenesis and development. However, the potential involvement of lncRNAs colon adenocarcinoma (COAD) needs to be further explored. All data used this study were obtained from The Cancer Genome Atlas database, all analyses conducted using R software. Basing on seven prognosis-related finally selected, we developed prognosis-predicting model with powerful effectiveness (training cohort, 1 year: AUC = 0.70, 95% Cl 0.57–0.78; 3 years: 0.71, 0.6–0.8; 5...
Glioblastoma multiforme (GBM) is the most aggressive and lethal subtype of gliomas central nervous system. The efficacy sonodynamic therapy (SDT) against GBM significantly reduced by expression apoptosis-inhibitory proteins in cells. In this study, an intelligent nanoplatform (denoted as Aza-BD@PC NPs) based on aza-boron-dipyrromethene dye phenyl chlorothionocarbonate-modified DSPE-PEG molecules developed for synergistic ferroptosis-enabled gas (GT) SDT GBM. Once internalized cells, NPs...
Interleukin (IL)‑1β is a member of the IL‑1 family proteins. receptor antagonist (IL‑1RA) an agent that binds to receptor, preventing from transmitting signals cells. The present study aimed identify role IL‑1β/1RA axis in epithelial‑mesenchymal transition (EMT), cell invasion, migration, proliferation and clone formation colorectal cancer (CRC) determine its underlying mechanisms action. Significantly increased expression both IL‑1β IL‑1RA was identified CRC patient data uploaded Cancer...
Colorectal cancer (CRC) has not only seriously affected people's lives, but also burdened the government healthcare system. Long non-coding RNAs (lncRNA) have attracted more and attention in study field.
The mesenchymal (MES) subtype of glioblastoma (GBM) is believed to be influenced by both cancer cell-intrinsic alterations and extrinsic cellular interactions, yet the underlying mechanisms remain unexplored.
Natural killer (NK) cells play a significant role in anti-tumor immunity, and their involvement has been documented various cancers. However, deeper understanding of the mechanisms by which NK influence gastric cancer progression remains necessary.
Trigeminal neuralgia (TN) is one of the most common causes facial pain. Microvascular decompression (MVD) first-choice surgical treatment. The present study aimed to develop a novel practical assessment system based on preoperative clinical and imaging factors for clinicians predict likelihood pain recurrence following MVD in TN. A total 56 patients with primary unilateral TN who underwent were retrospectively analyzed. Patients followed up observe 1 year after MVD. An online dynamic...
Abstract As one of the most common messenger ribonucleic acid modifications in eukaryotic organisms, N6‐methyladenosine (m6A) is involved a wide variety biological functions. The imbalance m6A RNA modification may be linked to cancer and other disorders, according growing body studies. Its effects on clear cell renal carcinoma (KIRC) have not been well discussed, though. Here, we acquired expression patterns 23 important regulators assess how they might fare KIRC. We observed that 17 major...
<title>Abstract</title> Background Gliomas, the most common malignant tumors of central nervous system, primarily originate from glial cells, which support nerve cells. Due to their high malignancy and aggressiveness, gliomas frequently result in poor prognoses. Increasing evidence suggests that long non-coding RNAs (lncRNAs) have diverse roles cancer; however, specific functions remain poorly understood. This study elucidates potential mechanisms lncRNA LINC00601 glioma. Methods...
Background Despite advances in neuro-oncology, treatments of glioma and tools for predicting the outcome patients remain limited. The objective this research is to construct a prognostic model using Homologous Recombination Deficiency (HRD) score validate its predictive capability glioma. Methods We consolidated datasets from TCGA, various cancer types pan-cancer HRD analysis, two additional RNAseq GEO CGGA databases. scores, mutation data, other genomic indices were calculated. Using...
Objective To explore the microsurgical treatment strategy of ruptured anterior communicating artery aneurysms.Methods From September 2009 to February 2013,thirty-three patients with aneurysms were treated clipping via modified pterion approach.The clinical and follow-up data analyzed retrospectively.Results At 3 44 months period followed-up after obtained in 32 patients.According Glasgow Outcome Score,the curative effects score 5 28 cases,four 2 cases,three 1 case death case.Conclusion...