A5011932563- Glioma Diagnosis and Treatment
- Signaling Pathways in Disease
- Immune cells in cancer
- interferon and immune responses
- Electrospun Nanofibers in Biomedical Applications
- Pituitary Gland Disorders and Treatments
- Circular RNAs in diseases
- RNA Research and Splicing
- 14-3-3 protein interactions
- Head and Neck Surgical Oncology
- Silk-based biomaterials and applications
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Wound Healing and Treatments
- Cancer Mechanisms and Therapy
- Meningioma and schwannoma management
- MicroRNA in disease regulation
Tianjin Medical University General Hospital
2021-2024
Anhui Medical University
2017-2021
Second Hospital of Anhui Medical University
2017-2021
Zhejiang University
2010
Abstract Glioblastoma is the most common primary intracranial malignant tumor in adults and has high morbidity mortality. TMEM158 been reported to promote progression of solid tumors. However, its potential role glioma still unclear. Here, we found that expression human cells core was significantly higher than noncancerous at edge using bioinformatics analysis. Cancer patients with GBMs harbored those WHO grade II or III gliomas. Interestingly, regardless grading, samples were IDH1-wild-type...
Glioma is the most common primary intracranial tumor and associated with poor prognosis. Identifying effective biomarkers for glioma particularly important. MXRA5, a secreted glycoprotein, involved in cell adhesion extracellular matrix remodeling has been reported to be expressed many cancers. However, role mechanism of action MXRA5 gliomas remain unclear. This study was aimed at investigating transcriptome level its clinical prognostic value. In this study, RNA microarray data 301 patients...
Abstract The tumor immunosuppressive microenvironment (IME) significantly affects occurrence, progression, and prognosis, but the underlying molecular mechanisms remain to make known. We investigated prognostic significance of PDPN its role in IME glioma. Weighted gene co-expression network analysis (WGCNA) found closely related IDH wildtype status higher immune score. Correlation suggested was highly positively relevant checkpoints expression block responding status. together with...