- Tracheal and airway disorders
- Cardiomyopathy and Myosin Studies
- Lipoproteins and Cardiovascular Health
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Lung Cancer Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Analytical Methods in Pharmaceuticals
- Esophageal and GI Pathology
- Peptidase Inhibition and Analysis
- Adipokines, Inflammation, and Metabolic Diseases
- Cancer, Lipids, and Metabolism
- Advanced Neural Network Applications
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Blood Pressure and Hypertension Studies
- Inflammatory mediators and NSAID effects
- Market Dynamics and Volatility
- Cancer-related molecular mechanisms research
- Airway Management and Intubation Techniques
- Congenital Heart Disease Studies
- Voice and Speech Disorders
- Antiplatelet Therapy and Cardiovascular Diseases
- Drug Transport and Resistance Mechanisms
- Heart Rate Variability and Autonomic Control
- Pharmacy and Medical Practices
- Hormonal Regulation and Hypertension
The Affiliated Yongchuan Hospital of Chongqing Medical University
2016-2025
Chongqing Medical University
2016-2025
Xidian University
2020-2025
Affiliated Hospital of Qingdao University
2024
Qingdao University
2024
Zhejiang University of Water Resource and Electric Power
2022-2023
Northeast Forestry University
2022
National University of Defense Technology
2021
Tongji University
2020-2021
Nanfang Hospital
2020
Cardiac fibroblasts (CFs) are the primary cell type responsible for cardiac fibrosis during pathological myocardial remodeling. Several studies have illustrated that pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone) attenuates in different animal models. However, effects of on fibroblast behavior not been examined. In this study, we investigated whether directly modulates is important remodeling such as proliferation, myofibroblast differentiation, migration and cytokine secretion. Fibroblasts...
Tiny machine learning (TinyML), executing AI workloads on resource and power strictly restricted systems, is an important challenging topic. This brief firstly presents extremely tiny backbone to construct high efficiency CNN models for various visual tasks. Then, a specially designed neural co-processor (NCP) interconnected with MCU build ultra-low TinyML system, which stores all features weights chip completely removes both of latency consumption in off-chip memory access. Moreover,...
Objectives This study aims to compare the protein composition of high-density lipoprotein (HDL) particles in coronary heart disease (CHD) patients and controls by proteomic methods. Background HDL has been reported exert pro-atherogenic properties CHD patients. Accumulating evidence indicates that composition, rather than HDL-C level, determines its functions. The changes involved conversion anti-atherogenic are currently unknown. Methods Results iTRAQ combined with nanoLC-MS/MS was...
Severe right ventricular hypertrophy (SRVH) is a rare phenotype in hypertrophic cardiomyopathy (HCM) for which limited information available. This study was undertaken to investigate the clinical, prognostic and genetic characteristics of HCM patients with SRVH.HCM SRVH defined as maximum wall thickness ≥10 mm. Whole-genome sequencing (WGS) performed SRVH. Multivariate Cox proportional hazards regression models were used identify risk factors cardiac death events Patients apical (ApHCM)...
Fine-grained visual categorization (FGVC) is a challenging task because there are many hard examples existing between fine-grained classes which differ subtly in particular local regions. To address this issue, methods have recourse to high-resolution source images and others adopt effective regularization like "mixup" or "between class learning." Despite their promising achievements, mixup tends cause the manifold intrusion problem would result under-fitting degradation of model performance...
Abstract Cone‐beam computed tomography (CBCT) system can provide real‐time 3D images and fluoroscopy of the region interest during operation. Some systems even offer augmented puncture guidance. The use CBCT for interventional pulmonary procedures has grown significantly in recent years, numerous clinical studies have confirmed technology's efficacy safety diagnosis, localization, treatment nodules. In order to optimize standardize technical specifications guide its application practice,...
Pulmonary fibrosis (PF) is a progressive and lethal disease with poor prognosis. S100A2 plays an important role in the progression of cancer. However, PF has not yet been reported. In this study, we explored potential its molecular mechanisms. Increased expression was first observed lung tissues patients. We found that downregulation inhibited transforming growth factor-β1 (TGF-β1)-induced epithelial–mesenchymal transition (EMT) A549 cells. Mechanically, TGF-β1 upregulated β-catenin...
Limited by huge computational cost, high inference latency and large memory consumption, existing 3D point cloud object detection methods are hard to be deployed on Internet of Things (IoT) edge devices. To handle this challenge, we present an extremely tiny framework termed TinyPillarNet. This leverages innovative pillar encoder represent as immensely pseudo-maps for shrinking the input sensing data. Moreover, a compact dual-stream feature extraction network is put forward respectively...
Background Alteration in the protein composition of high-density lipoprotein (HDL) has been proposed as a mechanism for development coronary heart disease (CHD). In HDL, an increase serum amyloid A (SAA) accompanying decrease apolipoprotein A-I (apoA-I) found during acute inflammation period. However, whether this phenomenon persists CHD patients, related to inflammation, is unknown. The purpose present study was explore relationship between SAA and apoA-I HDL isolated from patients. Methods...