Murat Küçük

ORCID: 0000-0003-1705-645X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Respiratory Support and Mechanisms
  • COVID-19 Clinical Research Studies
  • Sepsis Diagnosis and Treatment
  • Acute Kidney Injury Research
  • Long-Term Effects of COVID-19
  • Nosocomial Infections in ICU
  • Ultrasound in Clinical Applications
  • Anesthesia and Sedative Agents
  • Cardiovascular Syncope and Autonomic Disorders
  • Airway Management and Intubation Techniques
  • Cardiac Arrest and Resuscitation
  • SARS-CoV-2 and COVID-19 Research
  • Hemodynamic Monitoring and Therapy
  • Antibiotics Pharmacokinetics and Efficacy
  • Boron Compounds in Chemistry
  • Mass Spectrometry Techniques and Applications
  • Complement system in diseases
  • Synthesis of Organic Compounds
  • Intravenous Infusion Technology and Safety
  • Ion-surface interactions and analysis
  • Renal Diseases and Glomerulopathies
  • Nutrition and Health in Aging
  • Magnesium in Health and Disease
  • Anesthesia and Neurotoxicity Research
  • Thermal Regulation in Medicine

Atatürk University
1998-2025

Dokuz Eylül University
2021-2023

Izmir University
2022

Faculty (United Kingdom)
2022

Antalya IVF
2021

Gazi University
2015

Abstract Limited advancements in managing malignant brain tumors have resulted poor prognoses for glioblastoma (GBM) patients. Standard treatment involves surgery, radiotherapy, and chemotherapy, which lack specificity damage healthy tissue. Boron-containing compounds, such as boric acid (BA), exhibit diverse biological effects, including anticancer properties. This study aimed to examine whether boron supplementation, BA, can inhibit growth a xenograft animal model. Using MRI-based tumor...

10.1007/s12032-025-02600-z article EN cc-by Medical Oncology 2025-01-17

Mortality in critically ill patients with coronavirus disease 2019 (COVID-19) is high, therefore, it essential to evaluate the independent effect of new-onset atrial fibrillation (NOAF) on mortality COVID-19. We aimed determine incidence, risk factors, and outcomes NOAF a cohort COVID-19.We conducted retrospective study admitted intensive care unit (ICU) diagnosis was defined as that detected after COVID-19 without prior history. The primary outcome patients.NOAF incidence 14.9% (n = 37),...

10.1002/joa3.12619 article EN cc-by-nc-nd Journal of Arrhythmia 2021-08-16

The prediction of high-flow nasal oxygen (HFNO) failure in patients with coronavirus disease-2019 (COVID-19) having acute respiratory (ARF) may prevent delayed intubation and decrease mortality.

10.4274/balkanmedj.galenos.2021.2021-7-32 article EN cc-by-nc-nd Balkan Medical Journal 2021-03-15

Background Coronaviruses have been the cause of 3 major outbreaks during last 2 decades. Information on coronavirus diseases in pregnant women is limited, and even less known about seriously ill women. Data are also lacking regarding real burden disease 2019 (COVID-19) infection from low/middle-income countries. The aim this study was to determine characteristics clinical course COVID-19 pregnant/puerperal admitted ICUs Turkey. Methods This a national, multicenter, retrospective study....

10.1177/08850666231222838 article EN Journal of Intensive Care Medicine 2024-02-06

The most appropriate ventilatory mode during fiberoptic bronchoscopy is still not yet known clearly for patients with acute respiratory distress syndrome. Airway pressure release ventilation used as a recovery treatment severe In this study, the aim was to evaluate safety of process in syndrome ventilated airway and its effect on gas exchange mechanics.Single-center retrospective observational study performed intensive care unit tertiary referral center from September 2018 November 2019....

10.5152/turkthoracj.2022.21241 article EN cc-by-nc Turkish Thoracic Journal 2022-09-14

In this retrospective cohort study, we aimed to evaluate the incidence, risk factors and outcomes of amikacin-induced acute kidney injury (AKI) in critically ill patients with sepsis. A total 311 were included study. Of them, 83 (26.7%) had AKI. model 1, multivariable analysis demonstrated concurrent use colistin (OR 25.51, 95%CI 6.99-93.05, p< 0.001), presence septic shock during amikacin treatment 4.22, 1.76-10.11, p=0.001), Charlson Comorbidity Index 1.14, 1.02-1.28, p=0.025) as...

10.1080/1120009x.2022.2153316 article EN Journal of Chemotherapy 2022-12-05

To date, the coronavirus disease 2019 (COVID-19) caused more than 2.6 million deaths all around world. Risk factors for mortality remain unclear. The primary aim was to determine independent risk 28-day mortality.

10.3906/sag-2104-356 article EN other-oa TURKISH JOURNAL OF MEDICAL SCIENCES 2021-08-29

Although low serum magnesium level is a relatively common problem in mixed medical/surgical intensive care units (ICUs), its association with new-onset atrial fibrillation (NOAF) has been studied to lesser extent. We aimed investigate the effect of levels on development NOAF critically ill patients admitted ICU. A total 110 eligible (45 female, 65 male) were included this case-control study. The age and sex-matched control group (n = 110) no from admission discharge or death. incidence was...

10.1684/mrh.2023.0506 article EN Magnesium Research 2022-07-01

10.1016/s0020-7292(97)00232-4 article EN International Journal of Gynecology & Obstetrics 1998-01-01

Objective: Coronavirus disease 2019 (COVID-19) can cause acute respiratory distress syndrome (ARDS).Invasive mechanical ventilation (IMV) support and prone positioning are essential treatments for severe COVID-19 ARDS.We aimed to determine the combined effect of position airway pressure release (APRV) modes on oxygen improvement in mechanically-ventilated patients with COVID-19.Methods: This prospective observational study included 40 eligible (13 female, 27 male).Of patients, 23 (57.5%)...

10.4274/tjar.2022.22783 article EN Turkish Journal of Anaesthesiology and Reanimation 2023-06-01

Pleural fluid pH measurement is recommended for tube thoracostomy decisions in complicated parapneumonic pleural effusions. However, may be affected by blood critically ill patients with common systemic acid-base disorders. We aimed to investigate the use of lactate distinguish culture-positive effusions from other effusions.This prospective observational study included 121 eligible (51 female and 70 male). All effusion who underwent thoracentesis were assessed. was measured a gas...

10.5152/thoracrespract.2023.23021 article EN cc-by-nc Thoracic research and practice 2023-08-15

Giriş&#x0D; Acil serviste değerlendirilen kritik hastaların, üçüncü basamak yoğun bakım ünitesine yatış kriterlerini tanımlayarak, alt ve palyatif kapasite yetersizliğinin son bakımlara olan etkisini anlatmayı amaçladık.&#x0D; Gereç Yöntemler&#x0D; Hastanemizde 2016-2019 tarihleri arasında erişkin acil servisten anestezi yatışı yapılan 18 yaş üstü hastalar çalışmaya dahil edilmiştir. Hastaların arşiv dosyalarından hastane bilgi sisteminden edinilen demografik özellikleri, boyunca verilen...

10.18614/deutip.1292356 article TR Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi 2023-08-15

The effects of fiberoptic bronchoscopy are not elucidated in different mechanical ventilation modes. present study aimed to evaluate the on lung mechanics, parameters, and gas exchange 2 often-used modes, volume control pressure control, invasively ventilated patients followed up intensive care unit.Eligible were screened included after unit-fiberoptic database search. Patients who underwent under modes compared. primary outcome was occurrence any complication within first 24 hours...

10.5152/turkthoracj.2022.21149 article EN cc-by-nc Turkish Thoracic Journal 2022-03-30

Coronavirus disease 2019 is a novel viral infection that has caused pandemic globally. Many kinds of vaccine development studies were conducted to prevent the spread and deaths. The CoronaVac most commonly used in Turkey. Phase 3 trials from various countries revealed efficacy ranged 50.7% 91.25% but increased moderate or severe cases 100%. Additionally, it was remarkable owing high seroconversion rates achieving up After campaign began Turkey, critically ill patients continued admit our...

10.5152/turkthoracj.2022.0201 article EN cc-by-nc Turkish Thoracic Journal 2022-03-30

Acute kidney injury is strongly associated with mortality in critically ill patients coronavirus disease 2019 (COVID-19); however, age-related risk factors for acute are not clear yet. In this study, it was aimed to evaluate the effects of clinical on development an elderly COVID-19 patients.Critically (≥65years) admitted intensive care unit were included study. Primary outcome study rate injury, and secondary define effect frailty other mortality.A total 132 (median age 76 years, 68.2%...

10.55730/1300-0144.5488 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2022-01-01

Abstract Objectives: To determine the incidence, risk factors, and outcomes of new-onset atrial fibrillation (NOAF) in a cohort critically ill patients with coronavirus disease 2019 (COVID-19). Methods: We conducted retrospective study on admitted to intensive care unit (ICU) diagnosis COVID-19. NOAF was defined as that detected after COVID-19 without prior history. The primary outcome effect mortality patients. Results: enrolled 248 eligible incidence 14.9% (n=37), 78% (n=29) were men...

10.22541/au.161625416.61272781/v1 preprint EN Authorea (Authorea) 2021-03-20

Local anesthetics provide a loss of sensation on the injection site without causing consciousness and alteration in central control vital functions (1).However, local may cause responses, including irritation site, cellular toxicity, temporary neurological symptoms, systemic reactions such as anaphylaxis, methemoglobinemia, anesthetic toxicity (LAST) (2).The use high doses increases risk achieving toxic plasma levels.Accidental intravascular also LAST (2).In recent decades, using to regional...

10.4274/eamr.galenos.2022.47855 article EN European Archives of Medical Research 2023-03-01
Coming Soon ...