A5102920024- Tribology and Lubrication Engineering
- Genetics, Aging, and Longevity in Model Organisms
- Topological Materials and Phenomena
- Gear and Bearing Dynamics Analysis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Hydraulic and Pneumatic Systems
- Advanced machining processes and optimization
- Cellular Mechanics and Interactions
- Tribology and Wear Analysis
- Hedgehog Signaling Pathway Studies
- Control Systems in Engineering
- Lubricants and Their Additives
- 2D Materials and Applications
- Physics of Superconductivity and Magnetism
- Electronic and Structural Properties of Oxides
- Molecular Junctions and Nanostructures
- interferon and immune responses
- Plant-derived Lignans Synthesis and Bioactivity
- Tardigrade Biology and Ecology
- Nonmelanoma Skin Cancer Studies
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- Ocular Diseases and Behçet’s Syndrome
- IL-33, ST2, and ILC Pathways
- NF-κB Signaling Pathways
Shanghai Jiao Tong University
2017-2025
Xiamen University
2025
Nanjing University of Chinese Medicine
2025
Jiangsu Province Hospital
2025
Harbin University of Science and Technology
2024-2025
Sorbonne Université
2016-2025
Centre National de la Recherche Scientifique
2016-2025
Ministry of Education Science and Technology
2024
Target (United States)
2024
Institut de Biologie Paris-Seine
2016-2024
Stretchable electronics may enable electronic components to be part of our organs-ideal for future wearable/implantable biodiagnostic systems. One key challenges is failure the soft/rigid material interface due mismatching Young's moduli, which limits stretchability and durability current Here, we show that standing enokitake-like gold-nanowire-based films chemically bonded an elastomer can stretched up 900% are highly durable, with >93% conductivity recovery even after 2000...
Body axis elongation represents a fundamental morphogenetic process in development, which involves cell shape changes powered by mechanical forces. How mechanically interconnected tissues coordinate organismal development remains largely unexplored. During C. elegans elongation, cyclic forces generated muscle contractions induce remodeling of adherens junctions and the actin cytoskeleton epidermis, facilitating gradual embryo lengthening. While previous studies have identified key players...
Abstract Asthma exacerbations caused by respiratory viral infections are a serious global health problem. Impaired antiviral immunity is thought to contribute the pathogenesis, but underlying mechanisms remain understudied. Here using mouse models we find that Cullin5 (CUL5), key component of Cullin-RING E3 ubiquitin ligase 5, upregulated and associated with increased neutrophil count influenza-induced house dust mite-induced asthma. By contrast, CUL5 deficiency mitigates neutrophilic lung...
Chemotherapy-induced alopecia is a well-established cause of major distress to patients. Permanent chemotherapy-induced (PCIA) the absence or incomplete hair regrowth lasting longer than 6 months after cessation chemotherapy and it does not respond standard treatments scalp cooling topical minoxidil. The increasing numbers reports PCIA highlight need for research into an effective treatment. We report case 39 year-old woman with cosmetically significant continuous therapy oral
Alveolar macrophages (AMs) are specialized tissue-resident that orchestrate the immune response in allergic inflammation and asthma. However, what signals direct AMs to cross talk with other cells remains unclear. Here, we report autocrine motility factor receptor (AMFR), an endoplasmic reticulum–resident E3 ubiquitin ligase, is upregulated of asthma critical for this condition. AMFR deficiency significantly decreased allergy-induced T helper 2 (Th2) eosinophilic inflammation, less...
Purpose This paper aims to study the influence of cylindrical texture parameters on lubrication performance static and dynamic pressure thrust bearings (hereinafter referred as bearings) optimize their using multiobjective optimization. Design/methodology/approach The was studied based modified Reynolds equation. objective functions are predicted through BP neural network, were optimized improved ant lion algorithm (MOALA). Findings Compared with smooth surface, introduction can improve...
Purpose The purpose of this study is to investigate the influence rotational speed on oil film stability hydrostatic rotary table having double rectangular pads. evaluated based stiffness under constant load condition and displacement response amplitude disturbance condition. Design/methodology/approach theoretical equations cavity are deduced such as stiffness, damping dynamic equations. A simulation model developed analyze relationship among temperature, pressure fields stability....
An excessive inflammatory response in terminal airways, alveoli, and the lung interstitium eventually leads to pulmonary hypertension chronic obstructive disease. Proinflammatory cytokine interleukin-17A (IL-17A) has been implicated pathogenesis of diseases. MLN4924, an inhibitor NEDD8-activating enzyme (NAE), is associated with treatment various types cancers, but its role IL-17A-mediated not identified. Here, we report that MLN4924 can markedly reduce expression proinflammatory cytokines...
2H- and -phase monolayer MoTe2 films on highly oriented pyrolytic graphite are studied using scanning tunneling microscopy spectroscopy (STM/STS). The phase transition of can be controlled by a post-growth annealing process, the intermediate state during is directly observed STM. For 2H-MoTe2, inversion domain boundaries presented as bright lines at high sample bias, but dark lower bias. dI/dV mappings reveal distinct distributions electronic states between interiors domains. It should noted...
Abstract To enhance the loading capacity of oil film, reduce lubricating temperature, and minimize deformation friction pairs, three types concave textures were proposed. The tribological properties thrust bearing underwent multi-objective optimization analysis using two different methods. By comparing methods, it was found that improved algorithm (MOWCA) demonstrated better performance. Under this algorithm, when texture shape triangular, number 18n, size approximately 0.135 mm, spacing...
approximately 20% to 30% of patients. 1,2Characteristically, HFSR presents as painful, hyperkeratotic, erythematous plaques on the palms and soles in areas subject increased pressure.Other mucocutaneous effects described with anti-VEGF agents include keratoacanthoma, squamous cell carcinoma, splinter subungual hemorrhages, hair depigmentation, stomatitis. 2 Both systemic cutaneous toxic axitinib are consistent other same class, a significant incidence HFSR. 3,4Hand-foot skin reaction has...
Atomically flat superconducting NbN thin films have been grown on the SrTiO3 (111) substrate by plasma-assisted molecular beam epitaxy for first time. Using scanning tunneling microscopy and in situ reflection high energy electron diffraction, we investigate surface structure of epitaxial substrate. The orientation [101¯]NbN//[112¯]STO is dominating at temperature above 700 °C. quality as-grown can be further improved annealing elevated temperatures. homogeneous spatial distribution gaps...
Abstract Serum amyloid A (SAA) is an early and sensitive biomarker of inflammatory diseases, but its role in acute pancreatitis (AP) still unclear. Here, we used a caerulein‐induced mouse model to investigate the SAA AP other related responses. In our study, found that expression specific isoform, SAA3, was significantly elevated animal model. addition, SAA3‐knockout ( Saa3 −/− ) mice showed lower serum levels amylase lipase, tissue damage proinflammatory cytokine production pancreas...