A5016487732- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Research
- Metabolism, Diabetes, and Cancer
- Nutritional Studies and Diet
- Diabetic Foot Ulcer Assessment and Management
- Obesity, Physical Activity, Diet
- Folate and B Vitamins Research
- Cerebrovascular and Carotid Artery Diseases
- Diabetes Management and Education
- Peripheral Artery Disease Management
- Lipoproteins and Cardiovascular Health
- Cardiovascular Health and Risk Factors
- Antiplatelet Therapy and Cardiovascular Diseases
- Parkinson's Disease Mechanisms and Treatments
- Tuberculosis Research and Epidemiology
- Gout, Hyperuricemia, Uric Acid
- Erythropoietin and Anemia Treatment
- Mycobacterium research and diagnosis
- Alcohol Consumption and Health Effects
- Marine Invertebrate Physiology and Ecology
- Cardiovascular Disease and Adiposity
- Pharmacology and Obesity Treatment
- Biocrusts and Microbial Ecology
- Chronic Kidney Disease and Diabetes
Nanjing Medical University
2019-2021
Jiangsu Province Hospital
2010-2020
Jiangsu Provincial Hospital of Traditional Chinese Medicine
2014
Background Most cardiovascular diseases occur in low‐ and middle‐income regions of the world, but socioeconomic distribution within China remains unclear. Our study aims to investigate whether prevalence differs among high‐, middle‐, low‐income explore reasons for disparities. Methods Results We enrolled 46 285 individuals from 115 urban rural communities 12 provinces across between 2005 2009. recorded their medical histories calculated INTERHEART Risk Score assessment risk‐factor burden,...
Background The predictive value of adiposity indices and the newly developed index for cardiometabolic risk factors cardiovascular diseases ( CVD s) remains unclear in Chinese population. This study aimed to compare A Body Shape Index with other 5 conventional obesity‐related anthropometric (body mass index, waist circumference, hip waist‐to‐hip ratio, waist‐to‐height ratio) Methods Results total 44 048 participants were derived from baseline data PURE ‐China (Prospective Urban Rural...
Background: Serum uric acid has shown to be a predictor of renal disease progression in most but not all studies. This study aims test whether function-normalized serum is superior as the incident chronic kidney type 2 diabetes mellitus patients. Methods: In this study, 1339 patients with estimated glomerular filtration rate ⩾60 mL/min/1.73 m and normouricemia were included. Renal was calculated using acid/creatinine. Cox regression analysis used estimate association between acid, disease....
The aim of the present study is to validate Chinese version 8-item Morisky medication adherence scale (MMAS-8) in patients with type 2 diabetes mellitus (T2DM). A cross-sectional survey was conducted. After translation, a convenience sample 182 T2DM complete MMAS-8, and visual analogue scale. intraclass correlation coefficient Cronbach α were calculated determine reliability internal consistency, respectively. Validity confirmed using convergent, known group, construct validity. consistency...
Background To determine the frequency of chronic kidney disease (CKD) and its associated risk factors in Chinese type 2 diabetic patients, we conducted a cross-sectional study Nanjing, China, period between January 2008 December 2009. Methods Patients with diabetes under care by Jiangsu Province Official Hospital, China were invited for assessment. CKD was defined as presence albuminuria or estimated glomerular filtration rate <60 mL/min/1.73 m2. Albuminuria urinary albumin-to-creatinine...
The application of glycated hemoglobin (HbA(1c)) for the diagnosis diabetes is currently under extensive discussion. In this study, we explored validity using HbA(1c) as a screening and diagnostic test in Chinese subjects recruited Nanjing, China.In total, 497 (361 men 136 women) with fasting plasma glucose (PG) ≥ 5.6 mmol/L were to undergo oral tolerance (OGTT) test. Plasma lipid, uric acid, blood pressure also measured.Using receiver operating characteristic curve, optimal cutoff point...
This study aimed to investigate the prevalence of hyperhomocysteinemia (Hhcy) and its major determinants in Chinese urban population with new-onset hypertension.A total 574 adults (404 men 170 women) newly diagnosed primary hypertension were recruited from seven communities Nanjing, China. Data on lifestyle factors, such as physical activities, current smoking drinking status, dietary habits, familial factors collected interviews, laboratory examinations performed by well-trained personnel....
Abstract Aims/Introduction Anemia has a close interaction with renal dysfunction in diabetes patients. More proof is still awaited on the relationship between anemia and progression of disease this population. Materials Methods In present longitudinal study, 1,645 Chinese type 2 patients without end‐stage were included analysis Nanjing, China, during January 2006 December 2012. All managed by staged management protocol, clinical parameters collected at each visit. The end‐point was evaluated...
There remains controversy regarding which of the anthropometric indicators best defines obesity. In this study, we compared efficacy using body mass index (BMI), waist circumference (WC) and waist-to-hip ratio (WHR) in diagnosis obesity assessed their associations with diabetes, hypertension, dyslipidemia an urban working population China.Anthropometric measurements, blood pressure, plasma lipids, fasting 2-hour glucose (PG) levels by a 75 gram oral tolerance test (OGTT) were obtained from...
The aim of present study is to translate and validate a Chinese version the WIQ in patients with PAD T2DM. A cross-sectional survey was conducted. After translation, convenience sample 59 T2DM completed WIQ, SF-36 6MWT. ICC Cronbach’s alpha were calculated determine reliability internal consistency, respectively.Validity evaluated by correlation coefficients between 6MWD. consistency determined 0.93. Test—retest expressed Significant correlations observed 6MWD (ρ s =0.27 ∼0.88, p <...
<sec> <title>SETTING</title> The proportion of bacteriologically confirmed tuberculosis (TB) in China has decreased far below the worldwide average. </sec> <title>OBJECTIVE</title> To investigate whether stepwise measures to ensure sputum quality can improve rate TB. <title>DESIGN</title> We enrolled 980 adults with suspected TB from three counties during 2017 for this multicentre randomised controlled trial. Half participants (n = 490) were randomly assigned intervention groups that...
Based on the 24-week, prospective, non-interventional, observational study, A1chieve®, we investigated how health-related quality of life (HRQoL) changed, and predictors such changes, in Chinese people with type 2 diabetes mellitus (T2DM) after starting with, or switching to, biphasic insulin aspart 30 (BIAsp 30).In total, 8,578 T2DM treatment BIAsp were recruited from 130 urban hospitals China. HRQoL was assessed at baseline 24 weeks using EuroQol-5 dimensions (EQ-5D) questionnaire....
There is no consistent evidence for the relationship between tea-drinking and hyperhomocysteine (hHcy). Because habit hHcy have prevailed in Chinese hypertensive patients, this study aimed to investigate association tea consumption patients with hypertension.A total of 335 participants were recruited from 7 communities. Demographic characteristics collected through face-to-face interviews using a standard questionnaire, whereas laboratory data obtained within 1 week after patient...
To determine the safety of a higher starting dose basal insulin in overweight/obese patients with type 2 diabetes (T2D).This 16-week, randomized, multicentre, open-label trial enrolled adults T2D (body mass index 25-40 kg/m2 ) and suboptimal glycaemic control (glycated haemoglobin [HbA1c] 7.5-11.0% [58-97 mmol/mol] fasting plasma glucose [FPG] >9.0 mmol/L) two to three oral anti-hyperglycaemic drugs at 51 centres China. Patients were randomized (1:1) (0.3 U/kg) or standard (0.2 glargine 100...
Objective To compare and analyze clinical data, ulcer characteristics, prognosis hospitalization expenses in the patients with diabetic foot 2004 2012 China. Methods Diabetic disease data from 14 great three A hospitals 10 provinces or cities 15 11 China were collected analyzed, including medical history, physical biochemical examinations, demographic expenses. The classification, stage risk factors of also compared between two groups. t, χ2 u tests used for comparing groups data....
Background: Comprehensive management of diabetes should include its comorbid conditions, especially cardiovascular complications, which are the leading cause morbidity and mortality among patients with diabetes. Dyslipidemia is a condition risk factor for complications. Therefore, lipid level key managing successfully. However, it not clear that how well dyslipidemia managed in local Chinese health-care communities. This study aimed to assess low-density lipoprotein cholesterol (LDL-C) was...
Treatment with basal insulin in Chinese populations is currently sub-optimal, delayed initiation of treatment and inadequate dose titration. Increasing the initial may be a practicable effective solution to problem A higher will helpful for patients achieve blood glucose target improve satisfaction compliance as well require fewer steps titrate. Considering that overweight obese usually doses because resistance, feasible type 2 diabetes. However, safety an important issue needing considered...
The effect of dipeptidyl peptidase-4 (DDP-4) inhibitors versus α-glucosidase (AGIs) on the treatment type 2 diabetes mellitus (T2DM) in a real-world setting is unknown. aim this study was to compare glucose-lowering and tolerability vildagliptin as add-on metformin monotherapy (VM) AGI (AM) Chinese patients with T2DM. This subgroup analysis China Prospective Diabetes Study, post-marketing, prospective, observational, conducted at 52 centers China. T2DM inadequate glycemic control who...
The relationship between total plasma homocysteine (tHcy) and exercise remains controversial. This study aimed to investigate the association regular aerobic hyperhomocysteine (hHcy) in patients with hypertension.A of 497 hypertensive from 7 communities Nanjing were enrolled this cross-sectional study. All participants asked complete standard questionnaires by themselves. Physical laboratory examination performed within 1 week after enrollment. hHcy was estimated a multiple logistic...
To investigate the effects and mechanisms of cordycepin,an effective component cordyceps militaris, on renal interstitial fibrosis (RIF) its related eIF2α/TGF-β/Smad signaling pathway.Firstly, 15 C57BL/6 mice were randomly divided into 3 groups,the control group (Group A), model B) cordycepin-treated C). After fibrotic was successfully established by unilateral ureteral obstruction (UUO), in Group C intraperitoneally administrated with cordycepin(5 mg x kg(-1) d(-1)) ones A B physiological...