A5086526502- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Urban Green Space and Health
- Acute Myocardial Infarction Research
- Birth, Development, and Health
- Coronary Interventions and Diagnostics
- Nutritional Studies and Diet
- Cardiac Imaging and Diagnostics
- Blood Pressure and Hypertension Studies
- Global Health Care Issues
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Immune responses and vaccinations
- Health disparities and outcomes
- Noise Effects and Management
- Gestational Diabetes Research and Management
- Obesity, Physical Activity, Diet
- Cardiovascular Function and Risk Factors
- Sodium Intake and Health
- Maternal Mental Health During Pregnancy and Postpartum
- Catalytic C–H Functionalization Methods
- Immunodeficiency and Autoimmune Disorders
- Cardiac electrophysiology and arrhythmias
- Urban Transport and Accessibility
- Urban Heat Island Mitigation
Chinese Academy of Medical Sciences & Peking Union Medical College
2016-2025
University of California, Irvine
2020-2025
Chinese Academy of Sciences
2024-2025
Tianjin Medical University General Hospital
2025
Shanghai Sixth People's Hospital
2025
Shanghai Jiao Tong University
2025
Minzu University of China
2025
Qufu Normal University
2023-2024
Hefei Institutes of Physical Science
2024
Johns Hopkins University
2019-2024
Identification and treatment of hypertension in China remain suboptimal despite high prevalence increasing incidence stroke myocardial infarction.This study reported blood pressure levels, prevalence, awareness, treatment, control rates hypertension, addition to drug treatments China.This is a country-specific analysis 45 108 individuals, average age 51.4 (standard deviation 9.6) (35-70) years, enrolled between 2005 2009, from 70 rural urban communities 12 provinces.Among 18 915 (41.9%...
Background Most cardiovascular diseases occur in low‐ and middle‐income regions of the world, but socioeconomic distribution within China remains unclear. Our study aims to investigate whether prevalence differs among high‐, middle‐, low‐income explore reasons for disparities. Methods Results We enrolled 46 285 individuals from 115 urban rural communities 12 provinces across between 2005 2009. recorded their medical histories calculated INTERHEART Risk Score assessment risk‐factor burden,...
Epidemiological findings are inconsistent regarding the associations between air pollution exposure during pregnancy and gestational diabetes mellitus (GDM). Several limitations exist in previous studies, including potential outcome misclassification, unassessed confounding, lack of simultaneous consideration mixtures particulate matter (PM) constituents.To assess association GDM maternal residential to pollution, joint effect mixture pollutants PM constituents.Detailed clinical data were...
Recent studies have reported inconsistent associations between maternal residential green space and preterm birth (PTB, born < 37 completed gestational weeks). In addition, windows of susceptibility during pregnancy not been explored potential interactions with air pollution exposures are still unclear.To evaluate the relationships PTB, identify susceptibility, explore pollution.Birth certificate records for all births in California (2001-2008) were obtained. The Normalized Difference...
OBJECTIVE We investigated the association between historic redlining and risk of gestational diabetes mellitus (GDM), whether this relationship is mediated by maternal obesity area-level deprivation. RESEARCH DESIGN AND METHODS This retrospective study included 86,834 singleton pregnancies from Kaiser Permanente Southern California’s health records (2008–2018). Redlining was assessed using digitized Home Owners’ Loan Corporation (HOLC) maps, with patients’ residential addresses geocoded...
<h3>Importance</h3> The incidence of acute myocardial infarction has increased over the past decades in China, and management challenges include an unbalanced economy, disparate resources, variable access to medical care across nation. <h3>Objective</h3> To examine variations outcomes patients with ST-segment elevation among 3 levels hospitals typical Chinese public hospital model. <h3>Design, Setting, Participants</h3> This cross-sectional study used data from China Acute Myocardial...
Abstract Background. Exposure to high air temperature in late pregnancy is increasingly recognized as a risk factor for preterm birth (PTB). However, the combined effects of heatwaves with pollution and green space are still unexplored. In context climate change, investigating interaction between environmental factors identifying communities at higher important better understand etiological mechanisms design targeted interventions towards certain women during pregnancy. Objectives. To...
Benefits of green spaces on stress reduction have been shown in previous studies. Most existing studies to date focused the general population. However, there is a lack understanding physiological mechanisms underlying beneficial effects space among special populations, such as pregnant women. To examine and affective responses recovery women, using simulated exposure through virtual reality (VR). We recruited 63 women between 8 14 weeks' gestational age for laboratory experiment....
Little research exists regarding the relationships between green space and postpartum depression (PPD). We aimed to investigate PPD exposure, mediating role of physical activity (PA). Clinical data were obtained from Kaiser Permanente Southern California electronic health records in 2008–2018. ascertainment was based on both diagnostic codes prescription medications. Maternal residential exposures assessed using street view-based measures vegetation types (i.e., tree, low-lying vegetation,...
The rate of severe maternal morbidity (SMM) is continuously increasing in the US. Evidence regarding associations climate-related exposure, such as environmental heat, with SMM lacking.To examine between long- and short-term heat exposure SMM.This retrospective population-based epidemiological cohort study took place at a large integrated health care organization, Kaiser Permanente Southern California, January 1, 2008, December 31, 2018. Data were analyzed from February to April 2023....
Epidemiological findings regarding the association of particulate matter ≤2.5 μm (PM2.5) exposure with hypertensive disorders in pregnancy (HDP) are inconsistent; evidence for HDP risk related to PM2.5 components, mixture effects, and windows susceptibility is limited. We aimed investigate relationships between during pregnancy.
Backbone-enabled site-selective modification of peptides with benzoquinone via Pd-catalyzed δ-C(sp 2 )–H functionalization has been achieved.
Objectives. To (1) examine the disparity in availability of PurpleAir low-cost air quality sensors California based on neighborhood socioeconomic status (SES) and exposure to fine particulate matter smaller than 2.5 micrometers (PM ), (2) investigate temporal trend sensor distribution operation, (3) identify priority communities for future distribution. Methods. We obtained census tract–level SES variables PM concentrations from CalEnviroScreen4.0 data set. real-time (July 2017–September...
Intracellular degradation of HAPNs and inhibition PMCA activity jointly contributed to calcium overload in tumor cells, which then activated calpain-mediated mitochondrial apoptosis pathways, resulting cancer cell-specific toxicity.
Obesity has emerged as one of the most prevalent chronic diseases worldwide. Our study was conducted to investigate anti-obese potential novel probiotic Bifidobacterium longum subsp. infantis FB3-14 (FB3-14) and underlying molecular mechanisms in high-fat diet (HFD)-fed mice. The results demonstrated that an 8-week intervention significantly suppressed HFD-induced body fat weight gain abnormal alterations serum lipid parameter, restoring levels cholesterol (4.29 mmol/L) low-density...
There is minimal evidence of relationships between maternal air pollution exposure and spontaneous premature rupture membranes (SPROM), a critical obstetrical problem that can significantly increase fetal mortality morbidity. No prior study has explored the PROM risk related to specific components particulate matter with aerodynamic diameters ≤ 2.5 µm (PM2.5). We examined associations nitrogen dioxide (NO2), ozone (O3), PM2.5, PM10, PM2.5 constituents SPROM. A large retrospective cohort was...
The associations of exposure to fine particulate matter (PM2.5) and its constituents with spontaneous preterm birth (sPTB) remain understudied. Identifying subpopulations at increased risk characterized by socioeconomic status other environmental factors is critical for targeted interventions.