A5053044572- Mental Health Research Topics
- Functional Brain Connectivity Studies
- Sleep and related disorders
- Sleep and Wakefulness Research
- Tryptophan and brain disorders
- Complex Network Analysis Techniques
- COVID-19 epidemiological studies
- Circadian rhythm and melatonin
- Schizophrenia research and treatment
- COVID-19 and Mental Health
- Sleep and Work-Related Fatigue
- Behavioral Health and Interventions
- Attention Deficit Hyperactivity Disorder
- Chemistry and Stereochemistry Studies
- Health, Environment, Cognitive Aging
- Child and Adolescent Psychosocial and Emotional Development
- Child Nutrition and Feeding Issues
- Neural dynamics and brain function
- Health disparities and outcomes
- Treatment of Major Depression
- Digital Mental Health Interventions
- Climate Change Communication and Perception
- Health, Medicine and Society
- Advanced Neuroimaging Techniques and Applications
- Neuroscience and Music Perception
University of Amsterdam
2014-2025
Hologic (Germany)
2024-2025
Amsterdam University of the Arts
2024
Netherlands Institute for Neuroscience
2016-2024
Royal Netherlands Academy of Arts and Sciences
2016-2023
Amsterdam Neuroscience
2017-2021
Vrije Universiteit Amsterdam
2018-2019
Laboratoire d’immunologie intégrative du cancer
2018
Network analysis is entering fields where network structures are unknown, such as psychology and the educational sciences. A crucial step in application of models lies assessment structure. Current methods either have serious drawbacks or only suitable for Gaussian data. In present paper, we a method assessing from binary Although data infamous their computational intractability, computationally efficient model estimating structures. The approach, which based on Ising used physics, combines...
Statistical network models describing multivariate dependency structures in psychological data have gained increasing popularity. Such comparably novel statistical techniques require specific guidelines to make them accessible the research community. So far, researchers provided tutorials guiding estimation of networks and their accuracy. However, there is currently little guidance determining what parts analyses results should be documented a scientific report. A lack such reporting...
The COVID-19 pandemic imposes a long period of stress on people worldwide and has been shown to significantly affect sleep duration across different populations. However, decreases in quality rather than are associated with adverse mental health effects. Additionally, the one third general population suffering from poor was underrepresented previous studies. current study aimed elucidate effects COVID -19 levels pre-pandemic complaints as function worry. Participants (n = 667) Netherlands...
Abstract Study Objectives Major depressive disorder (MDD) is the leading cause of disability worldwide. Its high recurrence rate calls for prevention first-onset MDD. Although meta-analysis suggested insomnia as strongest modifiable risk factor, previous studies insufficiently addressed that might also occur a residual symptom unassessed prior depression, or comorbid complaint secondary to other depression risks. Methods In total, 768 participants from Netherlands Depression and Anxiety who...
Event-related potential (ERP) studies on attentional brain processes in insomnia disorder (ID) have yielded inconsistent findings. Such inconsistencies may relate to small sample sizes, limited corrections for multiple comparisons, and the possibility of heterogeneity within clinical population. We aimed overcome these limitations by studying ERP responses both across subtypes a larger ID. ERPs were recorded 201 participants with ID 70 normal sleeper controls (NS) an auditory oddball task....
Abstract Network theory, as a theoretical and methodological framework, is energizing many research fields, among which clinical psychology psychiatry. Fundamental to the network theory of psychopathology role specific symptoms their interactions. Current statistical tools, however, fail fully capture this constitutional property. We propose community detection tools means evaluate complex structure psychopathology, free from its original boundaries distinct disorders. Unique approach that...
Study ObjectivesObjective sleep impairments in insomnia disorder (ID) are insufficiently understood. The present study evaluated whether whole-night stage dynamics derived from polysomnography (PSG) differ between people with ID and matched controls dynamic features discriminate them better than conventional parameters.
Statistical network models describing multivariate dependency structures in psychological data have gained increasing popularity. Such comparably novel statistical techniques require specific guidelines to make them accessible the research community. In this literature, researchers previously provided tutorials guiding estimation of networks and their accuracy. However, there is currently little guidance determining what parts analyses results should be documented a scientific report. A lack...
Abstract It has been difficult to find robust brain structural correlates of the overall severity major depressive disorder (MDD). We hypothesized that specific symptoms may better reveal and investigated this for insomnia, both a key symptom modifiable risk factor MDD. Cortical thickness, surface area subcortical volumes were assessed from T1-weighted magnetic resonance imaging (MRI) scans 1053 MDD patients (age range 13-79 years) 15 cohorts within ENIGMA Working Group. Insomnia was...
Abstract Purpose To comprehend the complex relationship between symptoms and health-related quality of life (HRQoL) in patients with diffuse glioma, we applied symptom network analysis to identify patterns associations depression, cognition, brain tumor-related symptoms, HRQoL. Additionally, aimed compare global strength networks understand if are more tightly connected different subgroups patients. Methods We included 256 stratified sample based on disease status (preoperative vs....
BackgroundInsomnia disorder is the most common sleep disorder. A better understanding of insomnia-related deviations in brain could inspire treatment. Insufficiently recognized heterogeneity within insomnia population obscure detection involved circuits. In current study, we investigated whether structural connectivity differed between recently discovered and validated subtypes.MethodsStructural diffusion-weighted 3T magnetic resonance imaging data from 4 independent studies were harmonized....
Studies on personality traits and insomnia have remained inconclusive about which show the most direct associations with severity. It has moreover hardly been explored how relate to specific characteristics of insomnia. We here used network analysis in a large sample (N = 2089) obtain an integrated view both overall severity different characteristics, while distinguishing from indirect associations. first estimated describing among five factor model Overall was associated neuroticism,...
The principal goals of experimental psychopathology (EPP) research are to offer insights into the pathogenic mechanisms mental disorders and provide a stable ground for development clinical interventions. main message present article is that those better served by adoption Bayesian statistics than continued use null-hypothesis significance testing (NHST). In first part we list disadvantages NHST explain why limit conclusions can be drawn from EPP research. Next, highlight advantages...
Insomnia and chronic pain are highly prevalent conditions often comorbid. Somatic complaints other than also observed in insomnia. Poor sleep known to mutually reinforce each other. However, it is unknown whether the habitual severity of insomnia modulates acute effect a particularly bad night's on next day's severity, following quality. Using data from 3,508 volunteers (2,684 female, mean age 50.09 y), we addressed these questions addition associations between insomnia, somatic complaints,...
<b><i>Introduction:</i></b> The global disease burden of major depressive disorder urgently requires prevention in high-risk individuals, such as recently discovered insomnia subtypes. Previous studies targeting with fully automated eHealth interventions to prevent depression are inconclusive: dropout was high and likely biased, symptoms untreated participants on average improved rather than worsened. <b><i>Objective:</i></b> This randomized...
To investigate the association between self-reported sleep bruxism and insomnia their potential risk factors (eg, depression anxiety), to construct a network model with all these factors.We recruited 2251 participants from Netherlands Sleep Registry. All completed questionnaires on bruxism, insomnia, depression, anxiety, smoking frequency, alcohol caffeine consumption. The associations other variables were analyzed by univariate analysis, multivariate logistic regression, analysis.Although...