A5104651218- Sleep and Wakefulness Research
- Restless Legs Syndrome Research
- Parkinson's Disease Mechanisms and Treatments
- Obstructive Sleep Apnea Research
- Breast Lesions and Carcinomas
- Sleep and related disorders
- Metastasis and carcinoma case studies
- Signaling Pathways in Disease
- Ginseng Biological Effects and Applications
- Olfactory and Sensory Function Studies
- Breast Implant and Reconstruction
- Neuroscience of respiration and sleep
- Industrial Technology and Control Systems
- Sustainable Building Design and Assessment
- Cardiac Ischemia and Reperfusion
- Integrated Circuits and Semiconductor Failure Analysis
- Ergonomics and Musculoskeletal Disorders
- Advanced Data Storage Technologies
- Cardiac tumors and thrombi
- Medicinal Plants and Bioactive Compounds
- Sirtuins and Resveratrol in Medicine
- Infrared Thermography in Medicine
- Parallel Computing and Optimization Techniques
- Pharmacological Effects of Natural Compounds
- Breast Cancer Treatment Studies
Yunnan University of Traditional Chinese Medicine
2025
Mental Illness Research, Education and Clinical Centers
2025
Peking Union Medical College Hospital
2023-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024
Institute of Computing Technology
2024
Chinese Academy of Sciences
2024
Guangzhou University
2018-2024
University of Chinese Academy of Sciences
2024
Second Affiliated Hospital of Fujian Medical University
2023
Fujian Medical University
2023
Background and Purpose Activation of PKC‐ζ is closely linked to the pathogenesis cardiac hypertrophy. can be activated by certain lipid metabolites such as phosphatidylinositol (3,4,5)‐trisphosphate ceramide. However, its endogenous negative regulators are not well defined. Here, role sirtuin1‐PKC‐ζ signalling axis underlying molecular mechanisms were investigated in Experimental Approach Cellular hypertrophy cultures myocytes, from neonatal Sprague‐Dawley rats, was monitored measuring cell...
Abstract Idiopathic granulomatous mastitis (IGM), a recurrent inflammation disease of the non‐lactating breast, has had an increasing clinical morbidity rate in recent years, and its complicated symptoms unclear etiology make it challenging to treat. This rare benign inflammatory breast disease, centered on lobules, represents most type non‐puerperal (NPM), also known as mastitis. In this study, patients diagnosed with IGM (M, n = 23) were recruited cases, control (C, 17) enrolled controls....
The objective of this study was to evaluate the relationships between various sleep outcomes and circadian-sleep phase angles based on dim light melatonin onset predicted only from activity data. Actigraphy questionnaire data were obtained two independent datasets using National Sleep Research Resource: Multi-Ethnic Study Atherosclerosis Hispanic Community Health Study/Study Latinos Sueño visit. Predicted (pDLMO) calculated extended Kronauer limit-cycle model. Separate as length time pDLMO...
Both sleep disorders and pain decrease quality of life in patients with Parkinson's disease (PD). However, little is known about the relationship between objective disturbances PD. This study aimed to (1) examine clinical characteristics PD (2) explore correlation patients.Parkinson's (N = 144) underwent extensive evaluations motor nonmotor symptoms pain. Overnight video-polysomnography was also conducted. Clinical parameters were compared or without pain.Pain reported by 75 (52.1%), 49...
Minimizing the testing cost is crucial in context of design for test (DFT) flow. In our observation, patterns generated by commercial ATPG tools compression mode still contain redundancy. To tackle this obstacle, we propose a post-flow static compaction method that utilizes partial fault dictionary instead full dictionary, and leverages dedicated Pure-MaxSAT solver to re-compact tools. We also observe offer more comprehensive selection candidate "n-detect" mode, leading superior efficacy....
Pathologic cardiac hypertrophy (PCH) is a precursor to heart failure. Amydrium sinense (Engl.) H. Li (AS), traditional Chinese medicinal plant, has been extensively utilized treat chronic inflammatory diseases. However, the therapeutic effect of ASWE on PCH and its underlying mechanisms are still not fully understood.
Background: Breast cancer has become a critical international healthcare issue. Specifically, among the different subtypes, breast marked by human epidermal growth factor receptor 2 (HER2)-overexpression usually correlates with low survival and poor prognosis poses challenges in treatment, thus leading to high mortality. Case Description: A 54-year-old female patient was diagnosed large T4cN2aM0 stage IIIB tumor HER2 overexpression. The size large, there lack of opportunity for surgery....
To explore the intervention effect of traditional Chinese medicine hot pressing combined with health education in adolescents asthenopia, 92 asthenopia admitted to outpatient department Guangming Traditional Medicine Hospital Pudong New Area from October 2019 January 2021 were selected and randomly divided into two groups: control group test group, each 46 cases. Both received education. The was given sodium hyaluronate eye drops, ironing technique intervention. After 2 courses treatment,...
Breast Angiosarcoma can be divided into primary breast angiosarcoma (PBA) and second (SBA). PBA is rare malignant cancer with poor outcomes. usually occurs in women between 30-40 years old. does not have a specific clinical manifestation. Clinically, presents rapidly enlarging mass skin involvement color changes. Ultrasonography of hypoechoic or hyperechoic, mixed disordered areas. Microscopically, classified three grades according to the degree differentiation, grade related prognosis. And...
Granulomatous lobular mastitis (GLM) is characterized by nonspecific chronic inflammation concentrated in breast lobules. Surgical resection one of the most common treatment options for GLM. On basis our previous use Breast Dermo-Glandular Flap (BDGF), we designed a new surgical approach GLM, especially cases where focus close to nipple. Here describe this approach.In Peking Union Medical College Hospital (PUMCH) and Beijing Dangdai during January 2020-June 2021, enrolled all 18 GLM patients...
Objective To investigate the characteristics of objective sleep disturbances in Parkinson’s disease (PD) and factors related to it. Methods One hundred one PD patients 90 age- sex- matched controls underwent a video-polysomnography. The parameters its two groups were analyzed. Results Sleep latency was not statistically different comparing groups. had higher percentage non-rapid eye movement（non-REM）sleep stage 1 lower non-REM 2 compared with controls（27.9±17.8 vs...
Objective To evaluate the sleep structure and cognitive function in Parkinson’s disease (PD) patients with rapid eye movement (REM) behavior disorder (RBD)，and then explore correlation between PD RBD. Methods It was a cross-sectional study.Ninety-seven our center，including 39 RBD 21 age-and sex-matched idiopathic (iRBD) (control group)，37 without group)，underwent video-polysomnography to acquire parameters. Cognitive assessed Montreal Assessment (MoCA) on same day.A multiple linear...