A5021574779- Pelvic floor disorders treatments
- Pediatric Urology and Nephrology Studies
- Prostate Cancer Treatment and Research
- Urinary and Genital Oncology Studies
- Urinary Bladder and Prostate Research
- Urological Disorders and Treatments
- Kidney Stones and Urolithiasis Treatments
- Urinary Tract Infections Management
- Adrenal and Paraganglionic Tumors
- Urologic and reproductive health conditions
- Sarcoma Diagnosis and Treatment
- Bladder and Urothelial Cancer Treatments
- Renal and related cancers
- Genetic and Kidney Cyst Diseases
- Renal cell carcinoma treatment
- Testicular diseases and treatments
- Soft tissue tumor case studies
- Prostate Cancer Diagnosis and Treatment
- Fetal and Pediatric Neurological Disorders
- Cancer, Hypoxia, and Metabolism
- Genital Health and Disease
- Surgical Simulation and Training
- MRI in cancer diagnosis
- Teratomas and Epidermoid Cysts
- Neuroblastoma Research and Treatments
Kyorin University
2014-2025
Nara Medical University
2003-2007
This study aimed to assess the treatment preferences of Japanese patients with muscle-invasive bladder cancer (MIBC) by quantifying their trade-offs between attributes using a discrete choice experiment (DCE). A DCE was conducted among MIBC post-radical cystectomy. Participants were presented hypothetical options differing in such as efficacy Disease-free survival (DFS), side effects, administration, and cost. Preference data analyzed determine each attribute's relative importance (RI),...
Acute pyelonephritis (APN) with obstructive uropathy is not uncommon and often causes serious conditions including sepsis septic shock. We assessed the risk factors for shock in patients APN associated upper urinary tract calculi. retrospectively studied 69 calculi who were admitted to our hospital. Emergency drainage decompression of renal collecting system was performed empirical treatment cases failure initial severe cases. by multivariate logistic regression analysis. Overall, 45 (65.2...
Objective We examined whether androgen receptor splice variant 7 (AR‐V7) in circulating tumor cell(CTC)clusters can be used to predict survival patients with bone metastatic castration resistant‐prostate cancer (mCRPC) treated abiraterone or enzalutamide. Methods retrospectively enrolled 98 CRPC on enzalutamide, and investigated the prognostic value of CTC cluster detection (+ v −) AR‐V7 using a − based mRNA assay. ≤50% prostate‐specific antigen (PSA) responses, PSA progression‐free...
The Vesical Imaging Reporting and Data System (VI-RADS) was launched in 2018 to standardize reporting of magnetic resonance imaging for bladder cancer. This study aimed prospectively validate VI-RADS using a next-generation scanner investigate the usefulness denoising deep learning reconstruction.We enrolled 98 patients who underwent multiparametric before transurethral resection tumor. Tumors were categorized according VI-RADS, we ultimately analyzed 68 with pathologically confirmed...
Objectives This study aimed to investigate perioperative complications and the details of postoperative ureteral stricture after ureteroscopy with laser lithotripsy (URS‐L) for upper urinary tract stones in Japan. Methods Patient data on intra‐ using URS‐L were retrospectively collected from multiple centers Japan between April 2017 March 2020 cooperation Japanese Society Endourology Robotics. Data included number patients undergoing URS‐L, type complications, detailed characteristics...
To develop a modified Vesical Imaging Reporting and Data System (VI-RADS) without dynamic contrast-enhanced imaging (DCEI), termed "non-contrast-enhanced VI-RADS (NCE-VI-RADS)", to assess the additive impact of denoising deep learning reconstruction (dDLR) on NCE-VI-RADS.From January 2019 through December 2020, 163 participants who underwent high-gradient 3-T MRI bladder were prospectively enrolled. In total, 108 with pathologically confirmed cancer by transurethral resection analyzed....
To clarify the clinical factors including diagnostic imaging findings that may correlate with histopathological malignancy in primary retroperitoneal tumors.The backgrounds and of 22 benign 24 malignant tumors were retrospectively investigated, prognosis patients was assessed.There significant correlations between presence symptoms (P < 0.01), as well irregularity tumor margins 0.01). On dynamic magnetic resonance (MRI), 90% showed early enhancement either quick or slow washout, while 75%...
Abstract Background Acute pyelonephritis (APN) with obstructive uropathy often causes sepsis. Recently, sepsis was redefined using the sequential organ failure assessment (SOFA) score, based on new Sepsis-3 criteria. We investigated predictors for this definition in patients APN associated upper urinary tract calculi. Methods retrospectively evaluated who were admitted to our hospital treatment of Blood and urine samples collected before APN. Treatment included adequate antimicrobial therapy...
Objective: We examined whether epidermal growth factor receptor (EGFR) expression in circulating tumor cells (CTCs) can be used to predict survival a population of bone-metastatic castration-resistant prostate cancer (mCRPC) patients treated with docetaxel chemotherapy. Methods: All mCRPC who had experienced treatment failure androgen-deprivation therapy and received chemotherapy were eligible. CTCs EGFR enumerated the CellSearch System whole blood. This system is semi-automated that detects...
Many physicians encounter confusion and difficulty in distinguishing testicular torsion (TT) from of the appendix testis (TAT) patients with acute scrotum because overlapping signs symptoms. The objective our study was to evaluate clinical features that can help distinguish TT TAT.We performed a retrospective surgically confirmed TAT at institute January 1990 December 2013. Clinical findings, physical examination climatic conditions, laboratory data, color Doppler ultrasound (CDUS) findings...
The aim of the present study was to evaluate pathological and oncological outcomes laparoscopic radical prostatectomy (LRP) robot-assisted (RARP) performed by one surgeon at a single center.We evaluated 700 patients with localized prostate cancer (i.e., 250 received LRP 450 RARP) in study. clinicopathological outcomes, positive surgical margin (PSM) frequency, biochemical recurrence (BCR)-free survival were compared between RARP.At diagnosis, median patient age level prostate-specific...
Abstract Background Although the albumin-to-globulin ratio (AGR) is a promising biomarker for various malignancies, few studies have investigated its prognostic significance upper tract urothelial carcinoma (UTUC). Methods This retrospective study conformed to REporting recommendations tumour MARKer (REMARK) guideline. We reviewed 179 patients with UTUC who underwent radical nephroureterectomy at our institution between 2008 and 2018. Associations of preoperative clinicopathological factors,...
<b><i>Background:</i></b> Treatment of overactive bladder (OAB) with antimuscarinic agents has been shown to improve depression and/or anxiety symptoms. <b><i>Objectives:</i></b> The aim this study was evaluate the efficacy mirabegron on OAB symptoms and its effects treatment-naïve women OAB. <b><i>Methods:</i></b> Women treated were prospectively evaluated by symptom score hospital Scale before at 4 8 weeks after...
Abstract Background Vascular endothelial growth factor (VEGF) plays a major role in angiogenesis. One of the functions VEGF is to regulate neovascularization clear cell renal carcinoma (CCRCC). The objective our study was examine whether before nephrectomy serum levels or expression using immunohistochemistry (IHC) could predict postoperative recurrence nonmetastatic CCRCC. Results Twelve patients (14.5%) had during mean follow-up 52.6 ± 31.2 months. level significantly higher with than...
To examine whether pretreatment serum human epidermal growth factor receptor 2 (HER2/neu) and immunohistochemical HER2/neu expression predict biochemical recurrence-free survival in advanced prostate cancer.We studied 75 untreated patients with metastatic cancer compared them to a control group of 97 without histologically diagnosed cancer. Serum samples were collected for protein analysis before the started endocrine therapy. tissue was evaluated using analysis.Serum concentration...
<h2>Abstract</h2><h3>Objectives</h3> the prevalence of intracranial aneurysms and arachnoid cysts is higher in patients with autosomal dominant polycystic kidney disease (ADPKD) than general population. A genotype correlation was reported for aneurysms, but it unclear cysts. Therefore, investigated ADPKD. <h3>Materials Methods</h3> were screened by magnetic resonance imaging (MRI), <i>PKD</i> genotypes examined using next-generation sequencing 169 <h3>Results</h3> <i>PKD1</i>-, <i>PKD2</i>-...
This study was performed to evaluate the clinical and perioperative outcomes of laparoscopic retroperitoneal lymph node dissection (L-RPLND) open (O-RPLND) by one surgeon at a single center.We evaluated 30 patients with stage IIA germ cell tumors who underwent (15 L-RPLND 15 O-RPLND) our institution between April 1, 2010 March 31, 2018. The parameters were compared using approach those O-RPLND transperitoneal approach. There no significant differences in background characteristics two groups...
<b><i>Background:</i></b> Tolvaptan was approved for the treatment of autosomal dominant polycystic kidney disease (ADPKD). However, official indication “rapidly progressive disease” is described differently in clinical guidelines. We aim to define by risk ESRD, which evaluated using estimated height-adjusted total volume (HtTKV) growth rate. <b><i>Methods:</i></b> The ESRD retrospectively analyzed 617 initially non-ESRD adults with ADPKD and...
While gemcitabine/cisplatin (GC) is the gold standard regimen for patients with advanced urothelial carcinoma (aUC), either dose-reduced GC or gemcitabine/carboplatin (GCa) an alternative option "cisplatin-unfit" patients. However, few studies have compared outcomes these commonly used regimens in real-world setting.We retrospectively reviewed aUC who received full-dose GC, GCa as first-line salvage chemotherapy at two university hospitals between 2016 and 2020. Progression-free survival,...