Xueling Huang

ORCID: 0000-0003-1823-0499
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About
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Research Areas
  • Plant-Microbe Interactions and Immunity
  • Wheat and Barley Genetics and Pathology
  • Plant Disease Resistance and Genetics
  • Plant Stress Responses and Tolerance
  • Plant nutrient uptake and metabolism
  • Yeasts and Rust Fungi Studies
  • Fungal and yeast genetics research
  • Marine and coastal ecosystems
  • Algal biology and biofuel production
  • MicroRNA in disease regulation
  • Plant Gene Expression Analysis
  • Plant Micronutrient Interactions and Effects
  • Marine Toxins and Detection Methods
  • Genetic Mapping and Diversity in Plants and Animals
  • Plant Pathogens and Fungal Diseases
  • Ubiquitin and proteasome pathways
  • CRISPR and Genetic Engineering
  • Cancer-related molecular mechanisms research
  • Circular RNAs in diseases
  • Plant Pathogens and Resistance
  • Legume Nitrogen Fixing Symbiosis
  • Aquaculture Nutrition and Growth
  • Plant Reproductive Biology
  • Plant pathogens and resistance mechanisms
  • Venous Thromboembolism Diagnosis and Management

Northwest A&F University
2011-2025

Jinan University
2022-2025

First Affiliated Hospital of GuangXi Medical University
2024

Guangxi Medical University
2024

Wuxi Wind Power Design and Research Institute
2024

University of Twente
2019

Chongqing Three Gorges University
2016-2017

Sun Yat-sen University
2008-2013

Washington State University
2009-2013

Community Health Center
2012

Stripe rust, caused by Puccinia striiformis f. sp. tritici (Pst), is one of the most destructive diseases wheat. Here we report a 110-Mb draft sequence Pst isolate CY32, obtained using 'fosmid-to-fosmid' strategy, to better understand its race evolution and pathogenesis. The genome highly heterozygous contains 25,288 protein-coding genes. Compared with non-obligate fungal pathogens, has more diverse gene composition genes encoding secreted proteins. Re-sequencing analysis indicates...

10.1038/ncomms3673 article EN cc-by-nc-nd Nature Communications 2013-10-23

Summary Drought stress limits wheat production and threatens food security world‐wide. While ethylene‐responsive factors (ERFs) are known to regulate plant response drought stress, the regulatory mechanisms responsible for a tolerant phenotype remain unclear. Here, we describe positive role of TaERF87 in mediating tolerance stress. overexpression (OE) enhances tolerance, while silencing leads sensitivity wheat. RNA sequencing with biochemical assays revealed that activates expression proline...

10.1111/nph.18549 article EN New Phytologist 2022-10-20

The goal of this study was to determine the expression signature and potential role microRNAs in human arteries with arteriosclerosis obliterans (ASO).The profiles ASO normal control were determined by quantitative reverse transcription-polymerase chain reaction array. Among 617 detected microRNAs, multiple aberrantly expressed ASO. Some these dysregulated further verified reaction. them, microRNA-21 (miR-21) mainly located arterial smooth muscle cells (ASMCs) increased more than 7-fold that...

10.1161/atvbaha.111.229559 article EN Arteriosclerosis Thrombosis and Vascular Biology 2011-08-05

Abstract Reactive oxygen species (ROS) are vital for plant immunity and regulation of their production is crucial health. While the mechanisms that elicit ROS have been relatively well studied, those repress generation less understood. Here, via screening Brachypodium distachyon RNA interference mutants, we identified BdWRKY19 as a negative regulator whose knockdown confers elevated resistance to rust fungus Puccinia brachypodii. The three wheat paralogous genes TaWRKY19 induced during...

10.1093/plcell/koac001 article EN The Plant Cell 2022-01-05

Abstract Background Stripe rust of wheat, caused by Puccinia striiformis f. sp. tritici ( Pst ), is one the most important diseases wheat worldwide. Due to special features hexaploid with large and complex genome difficulties for transformation, without sexual reproduction hard culture on media, use genetic molecular techniques in studying genes involved wheat- interactions has been largely limited. The objective this study was identify transcriptionally regulated during an incompatible...

10.1186/1471-2229-10-9 article EN cc-by BMC Plant Biology 2010-01-12

Wheat stripe rust caused by the fungus Puccinia striiformis f. sp. tritici (Pst) is one of most destructive wheat diseases resulting in significant losses to production worldwide. The development disease-resistant varieties economical and effective measure control diseases. Altering susceptibility genes that promote pathogen compatibility via CRISPR/Cas9-mediated gene editing technology has become a new strategy for developing varieties. Calcineurin B-like protein (CBL)-interacting kinases...

10.1111/pbi.13956 article EN cc-by-nc-nd Plant Biotechnology Journal 2022-11-03

Stripe rust of wheat, caused by Puccinia striiformis f. sp. tritici, continues to cause severe damage worldwide. Durable resistance is necessary for sustainable control the disease. High-temperature adult-plant (HTAP) resistance, which expresses when weather becomes warm and plants grow older, has been demonstrated be durable. We conducted numerous studies understand molecular mechanisms different types stripe using a transcriptomics approach. Through comparing gene expression patterns with...

10.2174/1389202911314020004 article EN Current Genomics 2013-02-01

BAX inihibitor-1 (BI-1) is proposed to be a cell death suppressor conserved in both animals and plants. The ability of BI-1 genes inhibit programmed (PCD) has been well studied animals, but the physiological importance plant-microbe interactions remains unclear. This study characterized from wheat infected by Puccinia striiformis f. sp. tritici (Pst). deduced TaBI-1 protein contained Bax inhibitor domain seven transmembrane regions among members family. Transcription was detected all tissues...

10.1093/jxb/ers140 article EN Journal of Experimental Botany 2012-06-13

Abstract Soil salinity can adversely affect crop growth and yield, an improved understanding of the genetic factors that confer salt tolerance could inform breeding strategies to engineer salt‐tolerant crops improve productivity. Here, a group K + ‐preferring HKT transporters, TaHKT8 , TaHKT9 TaHKT10 were identified negatively regulate wheat shoot accumulation tolerance. A genome‐wide association study (GWAS) candidate gene analysis further revealed TaHKT9‐B substantially underlies natural...

10.1111/pce.14746 article EN Plant Cell & Environment 2023-10-24

Abstract Background Wheat stripe rust, caused by Puccinia striiformis f. sp. tritici ( Pst ), is one of the most destructive diseases wheat worldwide. To establish compatibility with host, forms special infection structures to invade plant minimal damage host cells. Although compatible interaction between and has been studied using various approaches, research on molecular mechanisms limited. The aim this study was develop an EST database infected in order determine transcription profiles...

10.1186/1471-2164-10-586 article EN cc-by BMC Genomics 2009-12-01

The obligate biotrophic fungus Puccinia striiformis f. sp. tritici (Pst) employs virulence effectors to disturb host immunity and causes devastating stripe rust disease. However, our understanding of how Pst regulate defense responses remains limited. In this study, we determined that the effector Hasp98, which is highly expressed in haustoria, inhibits plant immune triggered by flg22 or nonpathogenic bacteria. Overexpression Hasp98 wheat (Triticum aestivum) suppressed avirulent...

10.1111/jipb.13374 article EN Journal of Integrative Plant Biology 2022-10-01

Background Atherosclerosis is the primary cause of cardiovascular disease, carotid artery and peripheral vascular disease. However, it hard to obtain human arterial tissue at different stages atherosclerosis for a systematic study. The ApoE-deficient (ApoE -/- ) mice predictably develop spontaneous atherosclerotic plaques with numerous features similar lesions contain nearly entire spectrum observed during atherogenesis in humans. MicroRNA expression profiles were screened find out...

10.3760/cma.j.issn.0366-6999.20122289 article EN cc-by-nc-nd Chinese Medical Journal 2013-02-01

In cells, metallochaperones are important proteins that safely transport metal ions. Heavy metal-associated isoprenylated plant (HIPPs) contain a binding domain and CaaX isoprenylation motif at the carboxy-terminal end. To investigate roles of wheat heavy protein (TaHIPP) genes in development stress responses, we isolated cDNA encoding TaHIPP1 gene, which contains domain, nuclear localisation signals an (CaaX motif). Quantitative real-time PCR analysis indicated gene was differentially...

10.1111/plb.12344 article EN Plant Biology 2015-05-07

Pyrene, a representative polycyclic aromatic hydrocarbon, frequently occurs in aquatic environments and is associated with lethal impacts on humans wildlife. This study examined the impact of pyrene Alexandrium pacificum, dinoflagellate responsible for harmful algal blooms, their capability to bioremove pyrene. In 96 h exposure experiment, A. pacificum effectively reduced concentration seawater 50, 100, 200 μg/L, combined removal efficiency 96% seawater. Furthermore, noted significant...

10.1021/acs.est.4c08647 article EN Environmental Science & Technology 2025-01-09

Abstract The constitutive photomorphogenesis 9 (COP9) signalosome (CSN) is a versatile regulator of plant growth, development, and response to diverse pathogens. However, little research has been done understand the function those CSN genes in broad‐spectrum resistance In this study, we found that transcript levels wheat TaCSN5 were induced inoculation with Puccinia striiformis f. sp. tritici (Pst) treatment salicylic acid (SA). Overexpression Arabidopsis resulted increased susceptibility...

10.1111/mpp.13034 article EN cc-by-nc Molecular Plant Pathology 2021-01-24
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