Xi Chen

ORCID: 0000-0003-1857-6297
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About
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Research Areas
  • Osteoarthritis Treatment and Mechanisms
  • TiO2 Photocatalysis and Solar Cells
  • Advanced Photocatalysis Techniques
  • Circadian rhythm and melatonin
  • Knee injuries and reconstruction techniques
  • Fatty Acid Research and Health
  • Synthesis and Reactivity of Sulfur-Containing Compounds
  • Hemostasis and retained surgical items
  • Advanced Measurement and Metrology Techniques
  • Reconstructive Facial Surgery Techniques
  • Thyroid Cancer Diagnosis and Treatment
  • Advanced Nanomaterials in Catalysis
  • Surgical Sutures and Adhesives
  • Pneumothorax, Barotrauma, Emphysema
  • Reconstructive Surgery and Microvascular Techniques
  • Facial Rejuvenation and Surgery Techniques
  • Anorectal Disease Treatments and Outcomes
  • Abdominal Surgery and Complications
  • Catalytic Processes in Materials Science
  • Intensive Care Unit Cognitive Disorders
  • Organic and Molecular Conductors Research
  • Synthesis and biological activity
  • Diverticular Disease and Complications
  • Silk-based biomaterials and applications
  • Advanced Numerical Analysis Techniques

Soochow University
2011-2024

Wenzhou Medical University
2016

Sixth Affiliated Hospital of Sun Yat-sen University
2016

Sun Yat-sen University
2016

Affiliated Eye Hospital of Wenzhou Medical College
2016

Nantong University
2015

Taizhou People's Hospital
2015

Vanderbilt University Medical Center
2013

Abstract Hydroxyl radical ( • OH) with strong oxidation capability is one of the most important reactive oxygen species. The generation OH from superoxide radicals O 2 − ) an process in visible‐light‐driven photocatalysis, but conversion generally suffers slow reaction kinetics. Here, a hydrophobicity promoted efficient semiconductor‐mediated photodegradation reported. Hydrophobic TiO that synthesized by modifying surface thin polydimethylsiloxane (PDMS) layer and rhodamine B (RhB) are used...

10.1002/smll.202310128 article EN Small 2024-01-04

Recent evidence indicates that the mitochondrial functions of chondrocytes are impaired in pathogenesis osteoarthritis (OA). Melatonin can attenuate cartilage degradation through its antioxidant functions. This study aims to investigate whether melatonin could rescue OA and protect metabolism. showed a compromised matrix synthesis capacity associated with dysfunction aberrant oxidative stress. In vitro treatments promoted expression extracellular (ECM) components, improved adenosine...

10.1111/jpi.12815 article EN Journal of Pineal Research 2022-06-21

Reactive oxygen species (ROS) are implicated in induction of inflammatory response and cartilage degradation osteoarthritis (OA). Melatonin has been shown to improve the chondrogenic differentiation promote matrix synthesis mesenchymal stem cells. However, underlying mechanisms melatonin-regulated antioxidant activity OA not known. The aim this study was explore effect melatonin on nuclear factor-erythroid 2-related factor 2 (NRF2), a key transcription factor, its target genes early-stage...

10.1002/jbmr.4527 article EN Journal of Bone and Mineral Research 2020-12-01

Osteoarthritis (OA) is characterized by the progressive destruction of articular cartilage, which involved in imbalance between extracellular matrix (ECM) synthesis and degradation. MicroRNA-140-5p (miR-140) specifically expressed cartilage plays an important role OA-induced The aim this study was to investigate (1) whether intra-articular injection melatonin could ameliorate surgically induced OA mice (2) regulate matrix-degrading enzymes at posttranscriptional level targeting miR-140. In...

10.1155/2019/9705929 article EN Oxidative Medicine and Cellular Longevity 2019-12-14

Abstract Loss of extracellular matrix (ECM) cartilage due to oxidative stress injury is one the main characteristics osteoarthritis (OA). As a bioactive molecule derived from traditional Chinese Burdock , arctiin exerts robust antioxidant properties modulate redox balance. However, potential therapeutic effects on OA and underlying mechanisms involved are still unknown. Based Traditional Medicine Systems Pharmacology Database Analysis Platform (TCMSP) tool, -extracted small was identified as...

10.1186/s12951-022-01505-7 article EN cc-by Journal of Nanobiotechnology 2022-06-27

Osteoporosis can be associated with the disordered balance between osteogenesis and adipogenesis of bone marrow-derived mesenchymal stem cells (BM-MSCs). Although low-frequency mechanical vibration has been demonstrated to promote osteogenesis, little is known about influence acoustic-frequency vibratory stimulation (AFVS). BM-MSCs were subjected AFVS at frequencies 0, 30, 400, 800 Hz induced toward osteogenic or adipogenic-specific lineage. Extracellular matrix mineralization was determined...

10.1155/2015/540731 article EN cc-by BioMed Research International 2015-01-01

To compare the outcomes of modified Hotz procedure alone and combined with Z-epicanthoplasty for correction epiblepharon.Seventy-one Chinese patients who underwent epiblepharon repair were divided into 2 groups. In group 1, 33 (59 eyes) operated on procedure. 2, 38 (71 Z-epicanthoplasty. Treatment classified as "excellent" no cilium-ocular surface touching, "fair" 5 or fewer cilia-ocular touchings, "poor" more than touchings. Incision scars evaluated by Vancouver scar scale (VSS).There...

10.1097/iop.0000000000000664 article EN Ophthalmic Plastic and Reconstructive Surgery 2016-03-05

Treatment of [Et4N][Tp*W(μ3-S)3(CuBr)3] (Tp* = hydridotris(3,5-dimethylpyrazol-1-yl)borate) (1) with an excess α-methylpyridine (α-MePy) and NH4PF6 in CH2Cl2 afforded a cationic cluster [Tp*W(μ3-S)3Cu3(α-MePy)3(μ3-Br)](PF6) (2) while the reaction 1 1,4-pyrazine (1,4-pyz) MeCN–CH2Cl2 at 65 °C produced polymeric [Tp*W(μ3-S)3Cu3(1,4-pyz)((1,4-pyz)0.5)2(μ3-Br)][Tp*W(μ3-S)3(CuBr)3] (3). Reactions melamine (MA) : or 2 gave rise to another [{Tp*W(μ3-S)3Cu3Br(μ3-Br)}2(MA)2] (4) neutral...

10.1039/c1dt10230c article EN Dalton Transactions 2011-01-01

Purpose Osteoarthritis (OA) is a chronic degenerative joint disease. Sensory nerves play an important role in bone metabolism and the progression of inflammation. This study explored effects sensory nerve on OA at early stage mice.Materials Methods was induced via destabilization medial meniscus (DMM) C57BL/6 mice. denervation by subcutaneous injection capsaicin (90 mg/kg) one week prior to DMM. One after injection, tibia confirmed immunofluorescent staining. Four weeks DMM, micro-CT scans,...

10.1080/03008207.2019.1611796 article EN Connective Tissue Research 2019-07-05

Comprehensive Summary Photocatalysis is a promising green approach for water purification. The diversity of pH values key factor that restricts its practical application since affects the adsorption organic molecules, stability catalysts and photocatalytic performance. Here, we report pH–independent, efficient stable system with liquid (water)–liquid (oil)–solid (semiconductor) (L–L–S) triphase interface microenvironment. fabricated by coating thin layer silicon oil on surface ZnO nanowire...

10.1002/cjoc.202400618 article EN Chinese Journal of Chemistry 2024-09-04

From April 2011 to October 2013, 68 patients scheduled for complex hepatobiliary and pancreatic surgery underwent full-thickness suturing of abdominal incision with subcutaneous negative pressure drainage. There was no such complications as wound dehiscence or sinus formation. Except 2 cases infection, primary healing achieved. Two infected were followed up 1 year there incisional hernia. The plus drainage could prevent postoperative infection promote healing. And this simple practical...

10.3760/cma.j.issn.1671-7368.2015.01.017 article EN BMJ 2015-01-04

In this paper, the aspheric surface is discretized into a series of rings with different radius curvature, and toroidal-end cutter used to grind out each ring on basis generation method, finally enveloped by rings. Firstly, model locations established for milling surfaces using coordinates location calculated under maximum residual height, graphical user interface software programmed based MATLAB. Secondly, influence tool error machined profile analyzed. Finally, setting height 1 micron,...

10.1117/12.2587617 article EN Seventh Symposium on Novel Photoelectronic Detection Technology and Applications 2021-03-12
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