A5015796916- Diet and metabolism studies
- Gut microbiota and health
- Nutrition, Genetics, and Disease
- Malaria Research and Control
- Diverse Scientific Research Studies
- Neuroendocrine regulation and behavior
- Digestive system and related health
- Iron Metabolism and Disorders
- Cancer Research and Treatments
- Infant Health and Development
- Crop Yield and Soil Fertility
- Human-Animal Interaction Studies
- Diabetes Management and Research
- Epigenetics and DNA Methylation
- Blood Pressure and Hypertension Studies
- Hemoglobinopathies and Related Disorders
- Agricultural Science and Fertilization
- Dietary Effects on Health
- Mosquito-borne diseases and control
- Milk Quality and Mastitis in Dairy Cows
- Heme Oxygenase-1 and Carbon Monoxide
- Dermatology and Skin Diseases
- Photodynamic Therapy Research Studies
- Genomics, phytochemicals, and oxidative stress
- Agroforestry and silvopastoral systems
University of Tabuk
2018-2024
United States Postal Service
2021
Massachusetts Institute of Technology
2013-2018
National University of Malaysia
2014
Sudan University of Science and Technology
2013
Wound healing capability is inextricably linked with diverse aspects of physical fitness ranging from recovery after minor injuries and surgery to diabetes some types cancer. Impact the microbiome upon mammalian wound process poorly understood. We discover that supplementing gut lactic acid microbes in drinking water accelerates wound-healing occur half time required for matched control animals. Further, we find Lactobacillus reuteri enhances properties through up-regulation neuropeptide...
Radiant skin and hair are universally recognized as indications of good health. However, this 'glow health' display remains poorly understood. We found that feeding probiotic bacteria to aged mice induced integumentary changes mimicking peak health reproductive fitness characteristic much younger animals. Eating yogurt triggered epithelial follicular anagen-phase shift with sebocytogenesis resulting in thick lustrous fur due a bacteria-triggered interleukin-10-dependent mechanism. Aged male...
A recent epidemiological study showed that eating 'fast food' items such as potato chips increased likelihood of obesity, whereas yogurt prevented age-associated weight gain in humans. It was demonstrated previously animal models obesity the immune system plays a critical role this process. Here we examined human subjects and mouse consuming Westernized diet, found CD4+ T helper (Th)17-biased immunity changes microbial communities abdominal fat with after Western chow. In striking contrast,...
The decline of circulating testosterone levels in aging men is associated with adverse health effects. During studies probiotic bacteria and obesity, we discovered that male mice routinely consuming purified lactic acid originally isolated from human milk had larger testicles increased serum compared to their age-matched controls. Further investigation using microscopy-assisted histomorphometry testicular tissue showed Lactobacillus reuteri drinking water significantly seminiferous tubule...
Recent studies suggest health benefits including protection from cancer after eating fermented foods such as probiotic yogurt, though the mechanisms are not well understood. Here we tested mechanistic hypotheses using two different animal models: first model studied development of mammary when a Westernized diet, and second animals with genetic predilection to breast cancer. For model, outbred Swiss mice were fed chow putting them at increased risk for tumors. In this diet carcinogenesis was...
Muscle wasting, known as cachexia, is a debilitating condition associated with chronic inflammation such during cancer. Beneficial microbes have been shown to optimize systemic inflammatory tone good health; however, interactions between and host immunity in the context of cachexia are incompletely understood. Here we use mouse models test roles for bacteria muscle wasting syndromes. We find that feeding human commensal microbe, Lactobacillus reuteri, mice sufficient lower indices inhibit...
// Jessica R. Lakritz 1 , Theofilos Poutahidis 1, 2 Sheyla Mirabal Bernard J. Varian Tatiana Levkovich Yassin M. Ibrahim Jerrold Ward 3 Ellen C. Teng Brett Fisher Nicola Parry Stephanie Lesage Natalie Alberg Sravya Gourishetti James G. Fox Zhongming Ge Susan E. Erdman Division of Comparative Medicine, Massachusetts Institute Technology, Cambridge, MA 02139, USA Laboratory Pathology, Faculty Veterinary Aristotle University Thessaloniki, Greece 54124 Global VetPathology, Montgomery Village, MD...
Abstract Environmental factors are suspected in the increase of obesity and cancer industrialized countries but poorly understood. Here, we used animal models to test how future generations may be affected by Westernized diets. We discover long-term consequences grandmothers' utero dietary exposures, leading high rates frequent cancers lung liver two subsequent mice. Transgenerational effects were transplantable using diet-associated bacteria communities alone. Consequently, feeding...
The date fruit has been shown to possess several health benefits. This study aims determine the effects of consumption on onset and progression labour. A randomised controlled clinical was conducted 89 participants assess Twenty-six consumed fruits alone, 32 followed by drinking water. Thirty-one served as controls. There a significant positive impact consuming (rutab) maternal outcomes in both first third stages labour (p < 0.05 p 0.001, respectively). In addition, there relationship with...
The khat plant has been culturally used in many parts of Africa and the Arabian Peninsula for years to induce psycho-stimulating effect. Because global wide-spreading nature, chewing is being considered as a universally growing problem. Catha abbottii , edulis transvaalensis are three species commonly chewed Saudi Arabia nearby regions. Khat users usually prefer chew young leaves over mature ones due diverse effects produced by both. Though constituents have identified, complete...
Cohabitation with pet dogs imparts diverse health benefits to humans including a slim physique. It is known that neuropeptide hormone oxytocin fundamental in human-canine social bonds regulates appetite and body weight. was recently shown mice consuming Lactobacillus reuteri ATCC 6475 from human breast milk lowers weight up-regulates levels blood. Here we test the hypothesis bacteria dog saliva may similarly modulate recipient host We find spp isolate led lower when fed C57BL/6 wild type...
Diabetes mellitus is a chronic disease that significantly influences the patient's quality of life. This serious approaching an epidemic, and Arab countries are in diabetes super region. Improving life vital for good glycemic control. However, Therapy-Related Quality Life Questionnaire (DTR-QOL) not available Arabic. Thus, we aimed to validate questionnaire among patients with Saudi Arabia.
A field experiment was conducted during (2009/2010) season in Demonstration Farm of the Faculty Agricultural Studies, Sudan University Science and Technology at Shambat, Sudan.The objective to study effect fertilizers (urea, farmyard chicken manure) on nutritive value Rhodes grass.The fertilizer treatments used this were urea [U (100KgN/ha)], manure [FYM (5ton/ha)], [ CHM (3ton/ha)], combinations between them (U+FYM, U+CHM, FYM+CHM, U+FTM+CHM) with 8 cuts (Two monthes firstly monthly after...
A field experiment was conducted during (2009/2010) season in Demonstration Farm of the Faculty Agricultural Studies, Sudan University Science and Technology at Shambat, Sudan.The objective to study effect fertilizers (urea, farmyard chicken manure) on growth yield Rhodes grass.The fertilizer treatments used this were urea [U (100KgN/ha)], manure [FYM (5ton/ha)], [ CHM (3ton/ha)], combinations between them (U+FYM, U+CHM, FYM+CHM, U+FTM+CHM) with 8 cuts (Two months for first cut monthly after...
<ns3:p><ns3:bold>Background:</ns3:bold> Electronic devices for measuring blood pressure (BP) need to go through independent clinical validation as recommended by different authorities, both in general and specific populations. The aim of this study was assess the validity Omron RS6 (HEM-6221-E) wrist oscillometric obese Sudanese patients.</ns3:p><ns3:p> <ns3:bold>Methods:</ns3:bold> Of 90 individuals invited recruitment, 33 were included study, had their BP at level measured using standard...
BackgroundHypertension is a leading cause of mortality and morbidity worldwide.Hibiscus cheap readily available preparation. AimsWe aimed to assess the effect Hibiscus sabdariffa on blood pressure, lipid profile, plasma sugar, h-sensitive C-reactive protein. Methods This prospective cohort study conducted among 19College staff members at University Tabuk, Saudi Arabia during January 2020.The participants signed written informed consent, then responded questionnaire report their demographic...