Debabrata Chakraborty
A5016635981- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Venous Thromboembolism Diagnosis and Management
- Autoimmune Neurological Disorders and Treatments
- Mosquito-borne diseases and control
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Hereditary Neurological Disorders
- Long-Term Effects of COVID-19
- Vector-borne infectious diseases
- interferon and immune responses
- Moyamoya disease diagnosis and treatment
- Cerebral Venous Sinus Thrombosis
- Vasculitis and related conditions
- Glioma Diagnosis and Treatment
- Neurological Complications and Syndromes
- Atrial Fibrillation Management and Outcomes
- Infectious Diseases and Tuberculosis
- Neurological diseases and metabolism
- Peripheral Neuropathies and Disorders
- Infective Endocarditis Diagnosis and Management
- Amyloidosis: Diagnosis, Treatment, Outcomes
University of Calgary
2018-2024
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Calcutta National Medical College and Hospital
2023
Apollo Hospitals
2023
Creative Commons
2023
Apollo Gleneagles Hospitals
2020-2022
Virus Unit
2012
Alberta Stroke Program Early CT Score (ASPECTS) was devised as a systematic method to assess the extent of early ischemic change on noncontrast (NCCT) in patients with acute stroke (AIS). Our aim automate ASPECTS objectively score NCCT AIS patients.We collected images 5-mm thickness 257 (<8 hours from onset scans) followed by diffusion-weighted imaging acquisition within 1 hour. Expert readings DWI were used ground truth. Texture features extracted each region 157 training patient train...
Importance Age is a leading predictor of poor outcomes after brain injuries like stroke. The extent to which age associated with preexisting burdens changes, visible on neuroimaging but rarely considered in acute decision-making or trials, unknown. Objectives To explore the mediation functional outcome by markers frailty (hereinafter frailty) patients ischemic stroke receiving endovascular thrombectomy (EVT). Design, Setting, and Participants This cohort study was post hoc analysis Safety...
Background In this subanalysis of the TEMPO‐2 (Tenecteplase Versus Standard Care for Minor Ischaemic Stroke With Proven Occlusion) trial, a randomized clinical trial comparing tenecteplase and nonthrombolytic control in patients with minor stroke symptomatic intracranial occlusion, we investigated sex differences efficacy safety tenecteplase. Methods We compared outcomes after versus control, stratified by sex. also female male treated The primary outcome was “responder” outcome, defined as...
Background and Purpose- Intraluminal thrombus (ILT) is an uncommon finding among patients with ischemic stroke. We report clinical-imaging manifestations, treatment offered, outcome stroke/transient attack ILT in their cervico-cephalic arteries. Methods- Sixty-one of 3750 consecutive acute (within 24 hours onset) on initial arch-to-vertex computed tomography angiography from April 2015 through September 2017 constituted the prospective study cohort. Functional was assessed using modified...
<h3>Importance</h3> Some patients have poor outcomes despite small infarcts after endovascular therapy (EVT), while others with large do well. Understanding why these discrepancies occur may help to optimize EVT outcomes. <h3>Objective</h3> To validate exploratory findings from the Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion Emphasis on Minimizing CT Recanalization Times (ESCAPE) trial regarding pretreatment, treatment-related, posttreatment factors...
Brain frailty impairs the ability to compensate for brain dysfunction and is linked worse outcomes after stroke. Stroke severity at presentation a key determinant of in acute ischemic This study aimed examine impact on initial stroke recovery (AIS) patients undergoing endovascular thrombectomy (EVT). We conducted post hoc analysis ESCAPE-NA1 randomized-controlled trial that investigated efficacy safety neuroprotectant nerinetide with AIS who received EVT. markers (cortical atrophy,...
Abstract Japanese encephalitis virus (JEV) induces an acute infection of the central nervous system, pathogenic mechanism which is not fully understood. To investigate host response to JEV infection, 14‐day‐old mice were infected via extraneural route, resulted in and death. Mice that received immune splenocyte transfer protected from infection. Pathology gene expression profiles then compared brains either succumbed or by cell transfer. undergoing progressive had increased proinflammatory...
To detect the Japanese encephalitis virus (JEV) as etiologic agent from acute syndrome (AES) cases mainly amongst children and young adults vaccinated non-vaccinated districts of West Bengal. For detection JEV, a total 828 sera were referred non Bengal during 2005-2011. (JE) positive confirmed by ELISA RT-PCR method. Out cases, 245 samples method 46 291 162 (55.6%) below 20 years age. Initially in 2005, JE highest (0-20 years). After vaccination, although declined gradually districts, but...
Intracerebral hemorrhage (ICH) in a renal compromised state is unique situation where the pathophysiology of ailment, clinical scenario, management, and outcome differs from other situations. These patients have high morbidity mortality. In with very low eGFR ICH, one-month mortality rate was found to be 5.5 fold one-year 7.5 times more than normal function ICH.[1] They usually higher stroke score (NIHSS score) showing that impaired could associated severity.[1] Those moderate-to-severe...
A 38-year-old gentleman, following an uncomplicated dengue fever 2 weeks back, developed acute onset bilateral lower limb weakness and numbness for 5 days, associated with bladder bowel incontinence a band-like sensation in T4 dermatome. On examination, he had paraparesis normal cranial nerves except left upper motor neuron-type 7th nerve palsy higher mental function. Magnetic resonance imaging (MRI) of the brain spine detected multiple demyelinating lesions. diagnosis postdengue...
Story of an acute stroke and dual central nervous system infection - IJN- Print ISSN No: 2581-8236 Online No:- 2581-916X Article DOI 10.18231/j.ijn.2024.026, IP Indian Journal Neurosciences-IP J Neurosci
Statin in stroke: Are we using it properly? - IJN- Print ISSN No: 2581-8236 Online No:- 2581-916X Article DOI 10.18231/j.ijn.2024.010, IP Indian Journal of Neurosciences-IP J Neurosci
A 73-year-old man known case of giant cell arteritis (GCA) stopped taking his regular steroid. Within a few days, he presented to the emergency room with acute-onset dysarthria and left hemiparesis National Institutes Health Stroke Scale (NIHSS) 8. The computed tomography (CT) head was normal. CT angiography revealed free-floating thrombus at vertebral proximal basilar arteries. We administered injection tenecteplase (0.25 mg/kg body weight), NIHSS improved 3. did not proceed mechanical...
Using the immune system to its advantage, Salmonella Typhi initially invades gut followed by reticuloendothelial and nally nervous system, involvement of which usually occurs around second week fever. In developing countries, delayed diagnosis is predominantly due hesitation in seeking treatment. Our subject presented with fever since one week, altered mentation, headache neck pain; she was diagnosed enteric Although her neurological abnormality could be a complication infection, it...
Giant cell arteritis (GCA) is an immune-mediated vasculitis with intra and extracranial involvement commonly seen in the elderly population. However, a subgroup of patients may present constitutional symptoms only called “masked GCA.” We diagnosed successfully treated patient who initially presented cachexia, cognitive impairment, seizure. Clinicians need to be very suspicious about entity, as miss can lead life-threatening complications such stroke, arterial dissection, even aneurysm...
A 64-year-old gentleman, diabetic, and smoker attended the emergency room (ER) with acute stroke. He had expressive aphasia right upper limb weakness. His blood pressure was extremely high, he presented in final half an hour of permissible window period for thrombolysis. Bringing down his to make him eligible procedure within available time a real challenge us. Fortunately, we succeeded our attempt gradually improved. Truly, maximum allowable case still thrombolysis not clear explainable...
Introduction: Breast cancer is the most frequent malignancy in women and curable ~70-80% of patients with early-stage detection without complication. Paraneoplastic neurologic syndrome breast one such complication which often hard to diagnose, severely debilitating, also challenging treat. Materials Methods: A 57-year- old woman no known co-morbidity presented sudden onset altered sensorium. She was status epilepticus when brought emergency progressed super refractory in-spite our efforts....