A5101938492- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Semiconductor materials and interfaces
- Blood properties and coagulation
- Industrial Technology and Control Systems
- Polymer Foaming and Composites
- Advancements in Battery Materials
- Sulfur Compounds in Biology
- Silicon and Solar Cell Technologies
- Intracranial Aneurysms: Treatment and Complications
- Geoscience and Mining Technology
- Eicosanoids and Hypertension Pharmacology
- Advanced Condensed Matter Physics
- Peripheral Artery Disease Management
- Polymer crystallization and properties
- Cancer-related molecular mechanisms research
- Chalcogenide Semiconductor Thin Films
- Hydraulic and Pneumatic Systems
- Topological Materials and Phenomena
- Adipokines, Inflammation, and Metabolic Diseases
- Recycling and Waste Management Techniques
- RNA regulation and disease
- biodegradable polymer synthesis and properties
- Protease and Inhibitor Mechanisms
- Random lasers and scattering media
Inner Mongolia Normal University
2022-2025
Second Affiliated Hospital of Soochow University
2013-2024
Soochow University
2013-2024
Shandong University of Technology
2024
Zhengzhou University
2021-2023
Guangdong Institute of Intelligent Manufacturing
2022
Xidian University
2015
Shenzhen Metro (China)
2011
China Shenhua Energy (China)
2011
Shenhua Group (China)
2004
The manner in which hydrogen sulfide (H2S) suppresses neuroinflammation is poorly understood. We investigated whether H2S polarized microglia to an anti-inflammatory (M2) phenotype by activating AMP-activated protein kinase (AMPK).Three structurally unrelated donors (5-(4-hydroxyphenyl)-3H-1,2-dithiocyclopentene-3-thione [ADT-OH], (p-methoxyphenyl) morpholino-phosphinodithioic acid [GYY4137], and sodium hydrosulfide [NaHS]) enhanced AMPK activation BV2 microglial cells the presence absence...
Advanced glycation end-products (AGEs) contribute to the pathogenesis of diabetes mellitus and atherosclerosis by promoting vascular endothelial cell proliferation, migration, damage death. In this study, we examined role autophagy in HUVECs exposed AGE-modified bovine serum albumin (AGE-BSA). incubated with AGE-BSA for 6 h showed an increase formation acidic vesicular organelles autophagosomes. AGE-BSA-induced upregulation microtubule associated protein 1 light chain 3-II (LC3-II), a marker...
Hydrogen sulfide (H2S) is a gasotransmitter and potential therapeutic agent. However, molecular targets relevant to its actions remain enigmatic. Sulfide-quinone oxidoreductase (SQR) irreversibly oxidizes H2S. Therefore, SQR assumed inhibit H2S signaling. We now report that SQR-mediated oxidation of drives reverse electron transport (RET) at mitochondrial complex I, which, in turn, repurposes function superoxide production. Unexpectedly, I RET, process dependent on high membrane potential,...
The long non-coding RNA Brain-derived nutritional factor anti-sense (BDNF-AS) is a type of that has been proven to play crucial role in the occurrence and development certain nervous system disorders. However, molecular mechanism BDNF-AS Alzheimer's disease (AD) have not elucidated yet.Peripheral blood samples were collected from outpatients with AD as well normal elderly individuals community, expression was analysed using quantitative reverse transcription-polymerase chain reaction. An...
Contactin-associated protein 4 (Caspr4), also known as contactin-associated protein-like (CNTNAP4), is expressed in various regions of the brain. Recent reports suggest that CNTNAP4 a susceptibility gene autism spectrum disorders (ASDs). However, molecular function Caspr4 brain has yet to be identified. In this study, we show an essential role neural progenitor cells (NPCs). NPCs subventricular zone (SVZ), neurogenic region developing cortex. Knocking down enhances proliferation derived from...
The study theoretically investigates the flatbands in two-dimensional magnonic crystals (MCs) with kagome lattices based on plane-wave expansion method. In such MCs composed of ferromagnetic cylinders embedded another matrix, formation is due to spin waves localizing at a certain material small exchange constant. Moreover, position, number, and flatness can be adjusted by changing filling fractions. studies generating adjusting expand research content condensed matter physics thin film...
The impact of hyperfibrinogenemia on short-term outcomes after acute ischemic stroke (AIS) is still not well understood.We investigated the association between upon hospital admission and prognosis AIS patients.A total 3,212 patients enrolled from December 2013 to May 2014 across 22 hospitals in Suzhou city were included present study. Hyperfibrinogenemia was defined as having a serum fibrinogen＞4.0g/L. Cox proportional hazard logistic regression models used estimate effect all-cause...
Brain-derived neurotrophic factor (BDNF) provides neuroprotective effects towards therapeutic cerebral ischemia-reperfusion (I/R) injury. This view has been proposed by more and evidence. However, due to the lack of permeability blood-brain barrier (BBB) as well brief half-life in serum, clinical application is not widespread. To study participation exosomes containing BDNF I/R, we isolated from BDNF-overexpressing HEK293. The protective outcomes hypoxia/reoxygenation (H/R) experiments were...
Abstract Biodegradable ϕ 4 mm tubular porous poly(ε‐caprolactone)/poly(L‐lactide‐co‐ε‐caprolactone) (PCL/PLCL) scaffolds are fabricated successfully via one‐step microcellular supercritical carbon dioxide foaming process. The effect of blending ratio on the rheology, pore structures, mechanical property, wettability, and biocompatibility PCL/PLCL blends scaffold reported. Rheological results show that PCL matrix PLCL dispersed phase has good compatibility. melt strength can be enhanced...
Recently, the molecular mechanism responsible for instability of atherosclerotic plaques has gradually become a hot topic among researchers and clinicians. Matrix metalloproteinases (MMPs) vascular endothelial growth factor (VEGF) play an important role in processes formation development atherosclerosis. In this study, we established employed transwell co-culture system rabbit aortic cells smooth muscle to explore relationship between fibrin (Fb), fibrinogen (Fg), and/or their degradation...
Abstract This study aimed to compare the clinical efficacy of stenting compared with standardized medical treatment in patients moderate severe vertebral artery origin stenosis (VAOS). Patients diagnosed VAOS and indicated undergo were enrolled. divided into group group. All underwent transcranial Doppler (TCD) before after treatment. Incidence new cerebral infarction, transient ischemic attack (TIA), improvement symptoms, National Institutes Health Stroke Scale (NIHSS) score observed. A...
Purpose: To investigate the dosimetric accuracy of sliding window gated IMRT compared with static treatment, using varying dose rates.Materials and methods: This study measured changes in output diode array response changing rate, verified precision motion table, distribution film diodes at two depths rate.During 4DCT (4 Dimensional Computed Tomography), patient's respiratory signals target were recorded imported to XY4D simulation table SUN NUCLEAR Corporation simulate respiration tumour...
To investigate the feasibility, efficacy, and safety of endovascular recanalization for symptomatic chronic internal carotid artery occlusions (ICAO). Thirty patients with ICAO were treated using method. Proximal balloon protection devices used to prevent embolic migration by completely blocking blood flow. The morphology (ICA) at occluded segment based on catheter angiography was analyzed. Recanalization occlusion (CICAO) successful in 20 30 (66.7%). time required revascularization ranged...
The issue of saving energy and reducing environmental pollution has attracted enormous interest in developing lightweight plastic materials. As a cost-effective technology for manufacturing porous products, chemical foam injection molding (CFIM) become one the most widely used processes industry fields, especially automotive. However, it is still challenging to fabricate high-performance cellular products structural application. Herein, facile, efficient, easy-to-scale-up strategy was...
Considering that there are plenty of risk factors affecting hydraulic gear pumps wear life, multiple-factors assessment approach based on FAHP is proposed.Fuzzy consistent matrix constructed by applying fuzzy theory into conventional AHP to improve the precision judgments decision-makers.The relative importance pump wear-life has been effectively analyzed establishing life evaluation model.
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Abstract The effect of niobium ions with high‐valence doping on high‐voltage LiNi 0.5 Mn 1.5 O 4 (LNMO) materials was investigated. 1.5− x Nb prepared by high‐valent into material using the organic assisted combustion method. experimental samples were characterized scanning electron microscopy (SEM), transmission (TEM), X‐ray diffraction (XRD), photoelectron spectroscopy (XPS), electrochemical impedance (EI), and cyclic voltammetry (CV) analysis. results show that ‐doping changes orientation...
Meso-diaminopimelate dehydrogenase (meso-DAPDH) from Corynebacterium glutamicum ATCC13032 (CgDAPDH) is a type I meso-DAPDH that shows obvious preference toward meso-diaminopimelate (meso-DAP) and exhibits almost no amination activity 2-keto acids. There are seven distinct conserved insertions deletions (indels) between II meso-DAPDH. The current functional analysis of indels not comprehensive in Continuing our previous work on these indels, we first examined the functions other shown as...