Mariella Vieira Pereira Leão

ORCID: 0000-0003-1949-3207
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Oral microbiology and periodontitis research
  • Antifungal resistance and susceptibility
  • Probiotics and Fermented Foods
  • Salivary Gland Disorders and Functions
  • Essential Oils and Antimicrobial Activity
  • Gut microbiota and health
  • Infective Endocarditis Diagnosis and Management
  • Phytochemistry Medicinal Plant Applications
  • Oral health in cancer treatment
  • Streptococcal Infections and Treatments
  • Healthcare Regulation
  • Antimicrobial Peptides and Activities
  • Invertebrate Immune Response Mechanisms
  • Pneumocystis jirovecii pneumonia detection and treatment
  • Bone fractures and treatments
  • Dental Research and COVID-19
  • Hematopoietic Stem Cell Transplantation
  • Aquaculture disease management and microbiota
  • Women's cancer prevention and management
  • Dental materials and restorations
  • Dental Radiography and Imaging
  • Endodontics and Root Canal Treatments
  • Nail Diseases and Treatments
  • Medical Device Sterilization and Disinfection
  • Nosocomial Infections in ICU

Universidade de Taubaté
2013-2025

Universidade Estadual Paulista (Unesp)
2004-2024

Faculdade de Ciências Médicas de Minas Gerais
2023

Hospital Garcia de Orta
2015-2018

Universidade do Vale do Paraíba
2000

Imbalance in the resident microbiota may promote growth of opportunistic microorganisms, such as yeasts Candida genus and development diseases, especially aged people. This study evaluated whether consumption probiotic Yakult LBz(®) (Lactobacillus casei Bifidobacterium breve) was able to influence on specific immunological response against presence these oral cavity 42 healthy individuals. Saliva samples were collected before after use for 30 days, 3 times a week. The plated Dextrose...

10.1590/s0103-64402012000500011 article EN cc-by Brazilian Dental Journal 2012-10-01

The instruments and materials used in health establishments are frequently exposed to microorganism contamination, chemical products before sterilization reduce occupational infection. We evaluated the antimicrobial effectiveness, physical stability, corrosiveness of two commercial formulations peracetic acid on experimentally contaminated specimens. Stainless steel specimens were with Staphylococcus aureus, Escherichia coli, Candida albicans, blood, saliva then immersed a ready solution: 2%...

10.1590/1807-3107bor-2015.vol29.0038 article EN cc-by Brazilian Oral Research 2015-02-07

This study aimed to evaluate the capacity of Lactobacillus rhamnosus and/or its products induce synthesis cytokines (TNF‐ α , IL‐1 β IL‐4, IL‐6, IL‐10, and IL‐12) by mouse macrophages (RAW 264.7). Three microorganism preparations were used: live L . (LLR) suspension, heat‐killed (HKLR) supernatant a (SHKLR) which cultured with (37°C, 5% CO 2 ) for h 30 min. After that, cells 16 h. The supernatants used quantitation cytokines, ELISA. results compared induced lipopolysaccharide (LPS) analysed,...

10.1155/2015/716749 article EN cc-by The Scientific World JOURNAL 2015-01-01

The use of denture is known to increase the carriage Candida in healthy patients, and proliferation albicans strains can be associated with denture-induced stomatitis. aim this study was evaluate vinegar as an antimicrobial agent for control spp. complete upper wearers. Fifty-five patients were submitted a detailed clinical interview oral examination, instructed keep their dentures immersed 10% solution (pH less than 3) overnight 45 days. Before after experimental period, saliva samples...

10.1590/s1678-77572008000600006 article EN cc-by Journal of Applied Oral Science 2008-12-01

Abstract Background Inflammatory/immunological serum markers are useful for the early detection of organ dysfunction, helping diagnosis sepsis. Although blood biomarkers is a standard practice, use noninvasive samples (eg saliva) would be beneficial. Aim To investigate saliva hospitalized patients with and without sepsis identify levels inflammatory such as C‐reactive protein (CRP), procalcitonin (PCT), interleukin 6 (IL‐6) nitric oxide (NO). Methods Saliva were collected from 26 in...

10.1111/eci.13219 article EN European Journal of Clinical Investigation 2020-03-04

The study investigated whether the interaction with Lactobacillus rhamnosus (ATCC7469) interfere expression of virulence factors by Candida albicans (ATCC18804).These micro-organisms were grown in biofilms for 24, 48 and 72 h, was isolated major investigated. production phospholipase, protease haemolysin observed appropriate media; observation germ tubes formation serum; biofilm formation, after growth microtitre plates reading spectrophotometer. also tested antifungal sensitivity to...

10.1111/jam.13289 article EN Journal of Applied Microbiology 2016-09-08

Introduction: One of the therapeutic strategies for hematological malignancies is hematopoietic stem cell transplantation (HSCT). However, a common and severe post-transplantation complication graft-versus-host disease (GVHD), primarily mediated by donor’s immunocompetent cells, particularly T lymphocytes. Objectives: This study aims to explore potential biomarkers prognosis diagnosis GVHD following HSCT. Methods: integrative review was conducted using PubMed Google Scholar databases. The...

10.53855/bjt.v28i1.664_eng article EN cc-by Brazilian Journal of Transplantation 2025-03-17

Introdução: Uma das estratégias terapêuticas para neoplasias hematológicas é o transplante de células-tronco hematopoiéticas. No entanto, uma complicação comum e grave pós-transplante a doença do enxerto contra hospedeiro, mediada principalmente pelas células imunocompetentes doador, particularmente os linfócitos T. Objetivos: Este estudo tem como objetivo explorar potenciais biomarcadores prognóstico diagnóstico da hospedeiro após Métodos: Trata-se revisão integrativa realizada nas bases...

10.53855/bjt.v28i1.664_port article PT cc-by Brazilian Journal of Transplantation 2025-03-17

Probiotics are defined as microorganisms that promote benefits to host health, mainly by regulating resident microbiota. Disequilibrium in microbiota can favor the growth of opportunist and development pathologies, like candidosis caused yeasts Candida genus. This work evaluated whether probiotics consumption was able influence a specific immunological response presence these oral cavity. Saliva samples were collected from healthy individuals plated Dextrose Saboraud Agar with...

10.1590/s1517-83822009000400030 article EN Brazilian Journal of Microbiology 2009-10-08

To assess the effectiveness of three systems mechanical preparation to reduce Enterococcus faecalis within root canals.Twenty-four human single-rooted canine teeth were standardized a length 17 mm and canal contents removed using size 20 K-file, as last apical file. After irrigation sterilization, canals contaminated with E. incubated for 21 days at 37 °C 5% CO(2). Then, divided into groups with: ProTaper rotary system, manual system K-files. Samples contents, before after debridement,...

10.1111/j.1365-2591.2011.01994.x article EN International Endodontic Journal 2011-12-23

Adhesion and colonization of the oral cavity by Candida albicans is an initial step in candidosis. Orthodontic other appliances seem to favor candidal presence. The aim this work was compare presence species saliva, their adherence epithelial cells, levels anti–C. IgA children with or without orthodontic appliances. This study included 30 5 12 years old (9.1 ± 1.7 old) who were users removable devices for at least 6 months control similar ages (7.7 1.5 old). yeast saliva evaluated...

10.1590/s1806-83242013005000031 article EN cc-by Brazilian Oral Research 2014-01-01

To evaluate the presence of microorganisms genus Staphylococcus and Streptococcus on toys in playroom a teaching hospital, as well to analyze antimicrobial from isolated strains.Samples were collected 60 toys, using wet swabs, soon after being used by children. The samples inoculated enriched selective agar for isolation later identification microorganisms. Antibiogram testing was performed diffusion technique.The present 87.0% (52/60) toys. Seventythree strains isolated, with 29.0% (21/73)...

10.1590/0103-0582201432301 article EN cc-by-nc-nd Revista Paulista de Pediatria 2014-09-01

The role of matrix metalloproteinases (MMPs) in tissue degradation has become evident many diseases and great interest therefore exists the pharmacological control activity these enzymes. This study evaluated effect caffeic acid phenethyl ester (CAPE) on production MMPs their inhibitor (TIMP) monocytes activated by lipopolysaccharide (LPS). human monocytic cell line (THP-1) was treated with non-cytotoxic concentrations CAPE (10 60 μM) combined 1 μg/mL LPS. gene expression MMP-1, MMP-9 TIMP-1...

10.1016/j.archoralbio.2015.04.009 article EN publisher-specific-oa Archives of Oral Biology 2015-05-21

Antimicrobial therapy may cause changes in the resident oral microbiota, with increase of opportunistic pathogens. The aim this study was to compare prevalence Candida, Staphylococcus, Pseudomonas and Enterobacteriaceae cavity fifty patients undergoing antibiotic for pulmonary tuberculosis systemically healthy controls. Oral rinsing subgingival samples were obtained, plated Sabouraud dextrose agar chloramphenicol, mannitol MacConkey agar, incubated 48 h at 37ºC. Candida spp....

10.1590/s1517-83822011000400012 article EN Brazilian Journal of Microbiology 2011-12-01

To investigate the influence of Lactobacillus rhamnosus in expression virulence factors Candida albicans vitro.A suspension L. was initially grown MRS agar. The other day, Sabouraud dextrose agar added on growth lactobacilli and C. seeded for 24, 48 72 hours. strains were then isolated investigation ability biofilm formation, by means cultivation into 96 wells plaque, reading optical densities counting colony forming units per mL. Also germ tube formation investigated, after incubation horse...

10.1590/so100-720320150005217 article EN Revista Brasileira Ginecologia e Obstetrícia 2015-08-19

to correlate the presence of yeast from Candida genus in oral and vaginal cavity women with without vulvovaginal candidiasis (VVC), secretor IgA levels (IgAs) present saliva.among 51 included, 13 presented VVC 38 were Control Group. An amount 2.0 mL saliva stimulation was collected each patient, plus secretion using a swab, which then immersed physiological solution. Samples inseminated Sabouraud dextrose agar chloramphenicol for isolation counting colonies, isolated ones, phenotypically...

10.1590/s0100-72032008000600006 article EN cc-by Revista Brasileira Ginecologia e Obstetrícia 2008-06-01
Coming Soon ...