- Essential Oils and Antimicrobial Activity
- Oral microbiology and periodontitis research
- Phytochemistry Medicinal Plant Applications
- Endodontics and Root Canal Treatments
- Antifungal resistance and susceptibility
- Antimicrobial Peptides and Activities
- Complementary and Alternative Medicine Studies
- Aquaculture disease management and microbiota
- Phytochemistry and Biological Activities
- Invertebrate Immune Response Mechanisms
- Orthopaedic implants and arthroplasty
- Pomegranate: compositions and health benefits
- Dental materials and restorations
- Peptidase Inhibition and Analysis
- Bacterial biofilms and quorum sensing
- Titanium Alloys Microstructure and Properties
- Bone Tissue Engineering Materials
- Inflammatory mediators and NSAID effects
- Hydrogen's biological and therapeutic effects
- Therapeutic Uses of Natural Elements
- Bone and Dental Protein Studies
- Escherichia coli research studies
- Antibiotic Resistance in Bacteria
- Photodynamic Therapy Research Studies
- Medical and Biological Ozone Research
Universidade Estadual Paulista (Unesp)
2013-2024
Universidade Braz Cubas
2019-2020
Universidade Paulista
2017
Universidade de São Paulo
2015
Institute of Science and Technology
2013
Fundação Faculdade de Odontologia
2013
R. officinalis L. is an aromatic plant commonly used as condiment and for medicinal purposes. Biological activities of its extract were evaluated in this study, antimicrobial effect on mono- polymicrobial biofilms, cytotoxicity, anti-inflammatory capacity, genotoxicity. Monomicrobial biofilms Candida albicans, Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans Pseudomonas aeruginosa composed C. albicans with each bacterium formed microplates during 48 h exposed 5 min to (200...
This study aimed to evaluate the capacity of Lactobacillus rhamnosus and/or its products induce synthesis cytokines (TNF‐ α , IL‐1 β IL‐4, IL‐6, IL‐10, and IL‐12) by mouse macrophages (RAW 264.7). Three microorganism preparations were used: live L . (LLR) suspension, heat‐killed (HKLR) supernatant a (SHKLR) which cultured with (37°C, 5% CO 2 ) for h 30 min. After that, cells 16 h. The supernatants used quantitation cytokines, ELISA. results compared induced lipopolysaccharide (LPS) analysed,...
Titanium (Ti) and Ti-6 Aluminium-4 Vanadium alloys are the most common materials in implants composition but β type promising biomaterials because they present better mechanical properties. Besides of biomaterial, many factors influence performance biomaterial. For example, porous surface may modify functional cellular response accelerate osseointegration. This paper presents vitro vivo evaluations powder metallurgy-processed samples composed by different titanium pure Ti, aiming to show...
This study evaluated the action of Pfaffia paniculata K., Juglans regia L., and Rosmarius officinalis L. extracts against planktonic form biofilm Klebsiella pneumoniae (ATCC 4352). Minimum inhibitory concentration (MIC) minimum microbicidal (MMC) values were determined for each extract by microdilution broth method, according to Clinical Laboratory Standards Institute. Next, antimicrobial activity on was analyzed. For this, standardized suspension at 10 7 UFC/mL K. distributed into 96-well...
This study aimed to evaluate the effects of sodium hypochlorite (NaOCl), chlorhexidine (CHX), and glycolic extract propolis (GEP) as endodontic irrigants calcium hydroxide [Ca(OH)
This study evaluated the antifungal activity of Persea americana extract on Candida albicans biofilm and its cytotoxicity in macrophage culture (RAW 264.7). To determine minimum inhibitory concentration (MIC), microdilution broth (CLSI M27-S4 protocol) was performed. Thereafter, concentrations 12.5, 25, 50, 100, 200 mg/mL (n = 10) with 5 min exposure were analyzed mature microplate wells for 48 h. Saline used as control 10). After treatment, cells scraped off dilutions plated Sabouraud...
New drugs for the treatment of diabetes, glucagon-like peptide-1 (GLP-1) receptor agonists and inhibitors dipeptidyl peptidase-4 (DPP-4) have shown pleiotropic effects on bone metabolism anti-inflammatory properties. The aim this study is to evaluate exenatide (GLP-1 agonist) sitagliptin (DPP-4 inhibitor) during periodontitis induction by ligature insertion in rats.Forty rats were divided into four groups: 1) animals with induced that received (EG); 2) (SG); 3) without drug (LG); 4)...
Objective: Achyrocline satureioides “A.satureioides” is a subshrub, widely distributed in South America because of its medicinal properties. Although it used folk medicine, there still no approval for therapeutic use, and biocompatibility little explored. This study aimed to evaluate cytotoxicity genotoxicity over human gingival fibroblasts (FMM-1). Methodology: Ten different concentration the glycolic extract A.satureioides were tested 5min 24h contact with cells using MTT colorimetric...
This clinical study investigated the effects of endodontic treatment by using different irrigants (limewater + NaOCl and polymyxin B NaOCl) intracanal medication on endotoxins in teeth with primary infection radiographically visible apical periodontitis. Thirty-three necrotic pulp periapical lesions from patients were selected for this study. Samples collected after coronal opening (S1) instrumentation (S2). Root canals divided 3 groups (n = 11) according to irrigant combination used: LW:...
Abstract The aim of this study was to evaluate in vitro the effect calcium hydroxide [Ca(OH)2], 2% chlorhexidine gel (CHX) on macrophages (RAW 264.7) produce pro-inflammatory cytokines and nitric oxide after pretreatment with lipoteichoic acid (LTA) Enterococcus faecalis. Forty-eight human single-rooted teeth were instrumented R25.08 (RECIPROC) sterilized by gamma irradiation. LTA inoculated root canal each specimen for 96 hours. Specimens 40.06 50.05 medicated with: I) Pyrogen-free saline...
Background and Objective LP 533401 is an inhibitor of tryptophan hydroxylase 1, which regulates serotonin production in the gut. Previous work indicates that has anabolic effect bone. Thus, we hypothesized inhibition gut may modulate host response periodontal disease. In this study, aimed to analyze effects a rat periodontitis model evaluate role pathophysiology. Material Methods Twenty‐four rats were divided into three groups: treated group (T: ligature‐induced disease 533401, 25 mg/kg/d)...
This study evaluated conventional and alternative irrigation solutions combined with ultrasonic irrigant activation (UIA) against
Abstract The purpose of this study was to evaluate the antimicrobial effectiveness and dental applications ozonated water generated by portable equipment (0.667 mg/L). Total elimination C. albicans, E. coli S. mutans planktonic cells observed after 5 min. Reduction in number viable biofilms formed on acrylic resin for coli. same effect coli, aureus, albicans stainless steel. Ozonated effective disinfection experimentally contaminated toothbrushes. Keywords:...
Objective: Evaluating the antifungal potential ofEquisetum arvense L. (horsetail), Glycyrrhiza glabraL. (licorice), Punica granatum (pomegranate) andStryphnodendron barbatimam Mart. (barbatimão)extracts, after Candida albicans biofilm formationon acrylic resin. Material and methods: C. albicansstandard strain was cultured on Sabourauddextroseagar for 24 h at 37 °C. After standardizedin a spectrophotometer, 100 ?L of inoculum(106 cells/mL) sterile resin discwere maintained in Brain Heart...
Produtos naturais, como extratos glicólicos de plantas, são importantes para a aplicação clínica na área da saúde, em enxaguatórios bucais, cremes dentais e irrigação intracanal. Assim é necessário realizar estudos citotoxicidade desses glicólicos. O presente estudo buscou avaliar atividade citotóxica dos Cynara scolymus L. (alcachofra), Myracrodruom urundeuva Allem. (aroeira-do-sertão-do-sertão) Camellia sinensis (L.) Kuntze (chá verde) macrófagos camundongo (RAW 264.7) pelo teste...