A5062029117- Orthopedic Surgery and Rehabilitation
- Shoulder Injury and Treatment
- Elbow and Forearm Trauma Treatment
- Medical Malpractice and Liability Issues
- Bone fractures and treatments
- Orthopaedic implants and arthroplasty
- Hip disorders and treatments
- Hip and Femur Fractures
- Spine and Intervertebral Disc Pathology
- Total Knee Arthroplasty Outcomes
- Traumatic Ocular and Foreign Body Injuries
- Case Reports on Hematomas
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Diet and metabolism studies
- Orthopedic Infections and Treatments
- Shoulder and Clavicle Injuries
- Cardiac, Anesthesia and Surgical Outcomes
- Spinal Hematomas and Complications
- Streptococcal Infections and Treatments
- Diabetes and associated disorders
- Venous Thromboembolism Diagnosis and Management
- Adrenal Hormones and Disorders
- Tendon Structure and Treatment
- Bone and Joint Diseases
Oxford University Hospitals NHS Trust
2020-2025
University of Oxford
2019-2024
Nuffield Orthopaedic Centre
2005-2022
Imperial College London
2020-2022
Marymount University
2022
John Radcliffe Hospital
2022
Ronald Reagan UCLA Medical Center
2021
Windmill (United States)
2012-2020
Wellington Hospital
2018
Pharmac
2018
BackgroundManipulation under anaesthesia and arthroscopic capsular release are costly invasive treatments for frozen shoulder, but their effectiveness remains uncertain. We compared these two surgical interventions with early structured physiotherapy plus steroid injection.MethodsIn this multicentre, pragmatic, three-arm, superiority randomised trial, patients referred to secondary care treatment of primary shoulder were recruited from 35 hospital sites in the UK. Participants adults (≥18...
We developed a questionnaire to assess patient-reported outcome after surgery of the elbow from interviews with patients. Initially, 17 possible items five response options were included. A prospective study 104 patients (107 operations) was carried out analyse underlying factor structure, dimensionality, internal and test-retest reliability, construct validity responsiveness items. This compared Mayo Elbow performance score clinical scale, Disabilities Arm, Shoulder Hand questionnaire,...
As the English-language literature on prosthetic elbow arthroplasty contains only two comparative studies of implants in contemporary use, to our knowledge, comparisons performance is difficult. An improved knowledge outcomes would be valuable guiding implant selection.We identified three groups consecutive patients who had undergone with Souter-Strathclyde, Kudo, or Coonrad-Morrey for treatment rheumatoid arthritis. There were thirty-three elbows each group. All procedures done by under...
We present the histological findings of bone retrieved from beneath femoral components failed metal-on-metal hip resurfacing arthroplasties. Of a total 377 patients who underwent arthroplasty, 13 required revision; for fracture neck in eight, loosening component three and other reasons two. None these cases had shown evidence osteonecrosis at time initial implantation. Bone remnant head showed changes all but one case revision. In two which occurred within week implantation, were compatible...
Abstract Frozen shoulder is a spontaneously self-resolving chronic inflammatory fibrotic human disease, which distinguishes the condition from most diseases that are progressive and irreversible. Using single-cell analysis, we identify pro-inflammatory MERTK low CD48 + macrophages LYVE1 MRC1+ enriched for negative regulators of inflammation co-exist in frozen capsule tissues. Micro-cultures patient-derived cells integrin-mediated cell-matrix interactions between MERTK+ pro-resolving DKK3+...
Scaphoid fractures predominantly affect young men, in whom the UK smoking prevalence approaches 40%. We examined association between and failure of non-vascularized bone grafting screw fixation for scaphoid non-union delayed union a retrospective cohort study. Adequate follow-up was obtained 64 87 patients treated (74%). Union defined as presence trabecular continuity on at least two films from four-view radiographic series. achieved 47 cases. Seventeen were smokers. Thirteen 17 with smokers...
Tibial plateau fractures are peri-articular knee of the proximal tibia. The presentation is dependent on mechanism injury. tibial bony platform distal half joint, and made up a medial lateral condyle separated by intercondylar eminence. can vary greatly as result bimodal injury patient characteristics. should be assessed for life- limb-threatening injuries in accordance with British Orthopaedic Association Standards Trauma guidelines. Imaging undertaken to understand configuration fracture,...
Proximal humeral fractures are common with a bimodal distribution and sex discrepancy, affecting younger men older women. The presentation of proximal fracture can vary greatly because this the associated differences in mechanism injury. Initial management should involve assessment life- limb-threatening injuries as outlined by British Orthopaedic Association Standards for Trauma, particular attention paid to axillary nerve function vascular status. imaging orthogonal X-rays three planes...
Tendon stromal cells isolated from patients with chronic shoulder rotator cuff tendon tears have dysregulated resolution responses. Current therapies do not address the biological processes concerned persistent inflammation; therefore, new therapeutic approaches that target are required. We examined whether two specialized proresolving mediators (SPMs), lipoxin B4 (LXB4) and resolvin E1 (RvE1), modulate bioactive lipid mediator profiles of IL-1β-stimulated derived healthy volunteers. also...
Background Diabetic ketoacidosis (DKA) causes brain injuries in children ranging from subtle to life-threatening. Previous studies suggest that DKA-related injury may involve both stimulation of Na-K-Cl cotransport and microglial activation. Other implicate the cotransporter Ca-activated K channel KCa3.1 activation microglia ischemia-induced edema. In this study, we determined whether inhibiting cerebral or could reduce decrease inflammatory changes brain. Methods Using immunohistochemistry,...
Aims There is a lack of published evidence relating to the rate nonunion seen in occult scaphoid fractures, diagnosed only after MRI. This study reports delayed union and cohort patients with MRI-detected acute fractures. Methods multicentre at eight centres UK included all an fracture on MRI having presented acutely following wrist trauma normal radiographs. Data were gathered retrospectively for minimum 12 months each centre. The primary outcome measures surgery, union, nonunion. Results A...
BESS Surgical Procedure Guidelines (SPGs). Optimising Outcomes for Shoulder and Elbow patients. The British Society (BESS) SPGs are a series of evidence consensus Best Practice Recommendations developed by surgeons physiotherapists to help drive quality improvement achieve the best possible surgical outcomes UK This SPG on primary revision elbow replacement surgery is supported endorsed both Orthopaedic Association (BOA) Getting It Right First Time (GIRFT) Programme.
Aims To determine the role of early MRI in management suspected scaphoid fractures. Methods A total 337 consecutive patients presenting to an emergency department (ED) following wrist trauma over a 12-month period were prospectively included this service evaluation project. was not required 62 with clear diagnoses, and 17 managed as per pathway, leaving 258 normal series radiographs who then referred directly from ED for acute scan. Patient demographics, clinical details, outcomes,...
In our unit, children with developmental dysplasia of the hip or Perthes' disease, for whom an operation is considered, undergo examination under anaesthetic and a arthrogram. This prospective study assessed whether arthrogram modified treatment analysed reliability its interpretation. All undergoing disease over 12-month period were included. Treatment plans before after compared each three children's consultants. The preoperative arthrographic appearances blindly reviewed to monitor...
Aim of the study:To assess features identified on ultrasound in patients presenting with suspected extensor pollicis longus tendon rupture, and correlate this surgical findings.Material methods: A retrospective case series review was performed 11 (8 female, 3 male) rupture.All examinations were by an experienced musculoskeletal radiologist using a highresolution linear-array probe.The study evaluated associated sonographic appearances rupture correlated findings.Results: Rupture all cases...