Sinéad M. Williams

ORCID: 0000-0003-2011-5289
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About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 Research
  • Vector-Borne Animal Diseases
  • Viral Infections and Vectors
  • Influenza Virus Research Studies
  • Animal Disease Management and Epidemiology
  • SARS-CoV-2 detection and testing
  • Neonatal Respiratory Health Research

Australian Centre for Disease Preparedness
2020-2022

CSIRO Health and Biosecurity
2020-2022

Commonwealth Scientific and Industrial Research Organisation
2021

Coronavirus disease 2019 (COVID-19) caused by infection with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an systemic complications. Therapeutic strategies for COVID-19, including repurposing (partially) developed drugs are urgently needed, regardless of increasingly successful vaccination outcomes. We characterized two-dimensional (2D) and three-dimensional models (3D) to establish a physiologically relevant airway epithelial model potential investigating SARS-CoV-2...

10.3389/fphar.2022.813087 article EN cc-by Frontiers in Pharmacology 2022-03-11

The respiratory Influenza A Viruses (IAVs) and emerging zoonotic viruses such as Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pose a significant threat to human health. To accelerate our understanding of the host–pathogen response viruses, use more complex in vitro systems normal bronchial epithelial (NHBE) cell culture models has gained prominence an alternative animal models. NHBE cells were differentiated under air-liquid interface (ALI) conditions form pseudostratified...

10.3390/v12060679 article EN cc-by Viruses 2020-06-24

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an emerging virus that has caused significant human morbidity and mortality since its detection in late 2019. With the rapid emergence come unprecedented programme of vaccine development with at least 300 candidates under development. Ferrets have proven to be appropriate animal model for testing safety efficacy SARS-CoV-2 vaccines due quantifiable shedding nasal washes oral swabs. Here, we outline our efforts early outbreak...

10.1111/tbed.13978 article EN Transboundary and Emerging Diseases 2021-01-06

Abstract Bovine ephemeral fever is a vector-borne disease of ruminants that occurs in tropical and sub-tropical regions Africa, Asia Australia. The caused by rhabdovirus, bovine virus (BEFV), which as single serotype globally. Although several other closely related ephemeroviruses have been isolated from cattle and/or arthropods, only kotonkan Nigeria (tentatively) Mavingoni Mayotte Island the Indian Ocean previously associated with febrile disease. Here, we report isolation novel (Hayes...

10.1186/s13567-020-00781-1 article EN cc-by Veterinary Research 2020-04-29
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