A5056564828- Animal Disease Management and Epidemiology
- Viral Infections and Vectors
- Vector-Borne Animal Diseases
- SARS-CoV-2 and COVID-19 Research
- Viral gastroenteritis research and epidemiology
- Virology and Viral Diseases
- Influenza Virus Research Studies
- Microbial infections and disease research
- Mycobacterium research and diagnosis
- Animal Virus Infections Studies
- Tuberculosis Research and Epidemiology
- Genetic and phenotypic traits in livestock
- Mosquito-borne diseases and control
- Fish Ecology and Management Studies
- Wildlife Ecology and Conservation
- Zoonotic diseases and public health
- Species Distribution and Climate Change
- COVID-19 Clinical Research Studies
- SARS-CoV-2 detection and testing
- Viral Infections and Immunology Research
- Respiratory viral infections research
- Agroforestry and silvopastoral systems
- Rabies epidemiology and control
- Milk Quality and Mastitis in Dairy Cows
- COVID-19 epidemiological studies
Australian Centre for Disease Preparedness
2016-2025
Commonwealth Scientific and Industrial Research Organisation
2016-2025
Kafrelsheikh University
2016
King Faisal University
2016
University of Hong Kong
2016
National University of Singapore
2016
CSIRO Health and Biosecurity
2015
Animal, Food and Health Sciences
2013-2014
Veterinary Medicines Directorate
2002-2008
James Cook University
2001-2002
Several Avian paramyxoviruses 1 (synonymous with Newcastle disease virus or NDV, used hereafter) classification systems have been proposed for strain identification and differentiation. These pioneered efforts; however, they were based on different approaches lacked objective criteria the differentiation of isolates. differences created discrepancies among systems, rendering discussions comparisons across studies difficult. Although a system that was by Diel co-workers in 2012, ample...
Abstract Honeybee ( Apis mellifera ) health is threatened globally by the complex interaction of multiple stressors, including parasitic mite Varroa destructor and a number pathogenic viruses. Australia provides unique opportunity to study this viral landscape in absence V. . We analysed 1,240 A. colonies across reverse transcription-polymerase chain reaction (RT-PCR) next-generation sequencing (NGS). Five viruses were prevalent: black queen cell virus (BQCV), sacbrood (SBV), Israeli acute...
The viral landscape of the honey bee (Apismellifera) has changed as a consequence global spread parasitic mite Varroa destructor and accompanying virulent strains iflavirus deformed wing virus (DWV), which vectors. presence DWV in populations is known to influence occurrence other viruses, suggesting that current virome A. mellifera may be undercharacterized. Here we tested this hypothesis by examining Australia, uniquely free mites or DWV. Using high-throughput sequencing (HTS) approach,...
The 'D614G' mutation (Aspartate-to-Glycine change at position 614) of the SARS-CoV-2 spike protein has been speculated to adversely affect efficacy most vaccines and countermeasures that target this glycoprotein, necessitating frequent vaccine matching. Virus neutralisation assays were performed using sera from ferrets which received two doses INO-4800 COVID-19 vaccine, Australian virus isolates (VIC01, SA01 VIC31) either possess or lack but are otherwise comparable. Through approach,...
We conducted a challenge/rechallenge trial in which 3 alpacas were infected with Middle East respiratory syndrome coronavirus. The shed virus at challenge but refractory to further shedding rechallenge on day 21. indicates that may be suitable models for infection and dynamics of this virus.
Abstract Vaccines against SARS-CoV-2 are likely to be critical in the management of ongoing pandemic. A number candidates Phase III human clinical trials, including ChAdOx1 nCoV-19 (AZD1222), a replication-deficient chimpanzee adenovirus-vectored vaccine candidate. In preclinical efficacy challenge was evaluated ferret model infection. Groups ferrets received either prime-only or prime-boost administration via intramuscular intranasal route. All combinations resulted significant reductions...
In Lao People’s Democratic Republic pigs are kept in close contact with families. Human risk of infection pig zoonoses arises from direct and consumption unsafe products. This cross-sectional study was conducted Luang Prabang (north) Savannakhet (central-south) Provinces. A total 59 villages, 895 humans 647 were sampled serologically tested for zoonotic pathogens including: hepatitis E virus (HEV), Japanese encephalitis (JEV) Trichinella spiralis; addition, human sera Taenia spp....
Summary The paper is motivated by a problem in veterinary epidemiology, which spatially referenced breakdowns of bovine tuberculosis are classified according to their genotype and year occurrence. We develop nonparametric method for addressing spatial segregation the resulting multivariate point process, with associated Monte Carlo tests null hypothesis that different genotypes randomly intermingled no temporal changes segregation. Our estimates use kernel regression bandwidth selected...
Previous studies investigating long-distance, wind-borne dispersal of Culicoides have utilised outbreaks clinical disease (passive surveillance) to assess the relationship between incursion and event. In this study, species exotic isolates novel bluetongue viruses, collected as part an active arbovirus surveillance program, were used for first time into endemic region.A plausible event was determined five six cases examined. These include specimens which a possible identified within range...
Middle East respiratory syndrome coronavirus (MERS-CoV) infections continue to be a serious emerging disease problem internationally with well over 1000 cases and major outbreak outside of the region. While hypothesis that dromedary camels are likely source MERS-CoV infection in humans is gaining acceptance, conjecture continues original natural reservoir host(s) specifically role bats emergence virus. Dromedary were imported Australia, principally between 1880 1907 have since become large...
Abstract Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the infectious disease COVID-19, which has rapidly become an international pandemic with significant impact on healthcare systems and global economy. To assist antiviral therapy vaccine development efforts, we performed a natural history/time course study of SARS-CoV-2 infection in ferrets to characterise assess suitability this animal model. Ten each sex were challenged intranasally 4.64 × 10 4 TCID 50...
The introduction of novel bluetongue serotypes and genotypes into northern Australia is considered possible via the long‐distance windborne dispersal Culicoides (Diptera: Ceratopogonidae) vectors from Southeast Asia. Initial findings simulation modelling potential over a 15‐year period revealed that greatest risk for incursion island Timor occurs during December–March. regions at include top end Northern Territory Kimberley region in Western Australia, but there more widespread based on as...
Anaesthesia is sometimes required for the effective restraint of laboratory pigs sample collection. Yet, anaesthesia can initiate a range physiological disruptions that increase variability in study data and lead to poorer animal welfare. Judicious use mitigate experimental, human safety, welfare concerns, but it does not eliminate potential adverse effects. The reversal agents shorten recovery time reduce impacts also cause additional side We, therefore, trialled low-dose atipamezole (0.12...
Veterinary RecordVolume 162, Issue 12 p. 382-383 Short Communication Blood-based assays to detect Mycobacterium bovis -infected cattle missed by tuberculin skin testing M. Coad MSc, MSc TB Research GroupSearch for more papers this authorS. H. Downs PhD, S. PhD Centre Epidemiology and Risk Analysis, Laboratories Agency (VLA) — Weybridge, Woodham Lane, Addlestone, Surrey, KT15 3NBSearch authorP. A. Durr BVSc, MRCVS, Corresponding Author P. MRCVS n/a@dne.dne 3NBDr Durr's present address is...
Hendra virus (HeV) is an important emergent in Australia known to infect horses and humans certain regions of the east coast. Whilst pteropid bats ("flying foxes") are considered natural reservoir HeV, which four mainland species principal has been a source ongoing debate, particularly as shared roosting common. To help resolve this, we sampled colony consisting just one these species, grey-headed flying fox, (Pteropus poliocephalus), at southernmost extent its range. Using pooled urine...
Invasive wildlife often causes serious damage to the economy and agriculture as well environmental, human animal health. Habitat models can fill knowledge gaps about species distributions assist planning mitigate impacts. Yet, model accuracy utility may be compromised by small study areas limited integration of ecology or temporal variability. Here we modelled seasonal habitat suitability for wild pigs, a widespread harmful invader, in northern Australia. We developed resource-based,...
Although vaccination of poultry for control highly pathogenic avian influenza virus (HPAIV) H5N1 has been practiced during the last decade in several countries, its effectiveness under field conditions remains largely unquantified. Effective HPAI is however essential preventing incursions, silent infections and generation new antigenic variants. The objective this study was to asses level duration vaccine induced immunity commercial layers Indonesia. Titres haemagglutination inhibition (HI)...
The respiratory Influenza A Viruses (IAVs) and emerging zoonotic viruses such as Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) pose a significant threat to human health. To accelerate our understanding of the host–pathogen response viruses, use more complex in vitro systems normal bronchial epithelial (NHBE) cell culture models has gained prominence an alternative animal models. NHBE cells were differentiated under air-liquid interface (ALI) conditions form pseudostratified...