Francesca Castro
A5070014570- Nutrition, Genetics, and Disease
- Multiple Myeloma Research and Treatments
- Nutrition, Health and Food Behavior
- Complementary and Alternative Medicine Studies
- Hemoglobinopathies and Related Disorders
- Nutritional Studies and Diet
- Signaling Pathways in Disease
- Tannin, Tannase and Anticancer Activities
- Nutrition and Health in Aging
- Phytoestrogen effects and research
- Inflammatory Biomarkers in Disease Prognosis
- Amyotrophic Lateral Sclerosis Research
- Cancer, Lipids, and Metabolism
- Histone Deacetylase Inhibitors Research
- Nuts composition and effects
- Alzheimer's disease research and treatments
- Dietetics, Nutrition, and Education
- Hematological disorders and diagnostics
- Pharmacological Effects and Toxicity Studies
- Toxin Mechanisms and Immunotoxins
- Statistical Methods and Inference
- Neutropenia and Cancer Infections
- Child Nutrition and Feeding Issues
- Cardiac Structural Anomalies and Repair
- Plant Physiology and Cultivation Studies
Memorial Sloan Kettering Cancer Center
2022-2025
Kettering University
2023-2025
Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo
2024
University of Palermo
2023
Abstract Correlating time-dependent patient characteristics and matched microbiome samples can be helpful to identify biomarkers in longitudinal studies. Existing approaches typically repeat a pre-specified modeling approach for all taxonomic features, followed by multiple testing adjustment step false discovery rate (FDR) control. In this work, we develop an alternative strategy of using logratio penalized generalized estimating equations, which directly models the characteristic interest...
Abstract Background: Multiple myeloma (MM), the second most common hematologic malignancy in US, has seen improved survival with therapeutic advancements. This presents an opportunity to enhance outcomes through diet and lifestyle. Poor dietary habits obesity are linked adverse MM its precursors—monoclonal gammopathy of undetermined significance (MGUS) smoldering multiple (SMM)—potentially mediated by intestinal dysbiosis which affects immune microenvironment. High Healthy Eating Index (HEI)...
Abstract Aims Neuroinflammation might be involved in the degeneration and progression of Amyotrophic Lateral Sclerosis (ALS). Here, we studied role circulating lymphocytes ALS, particular NK cells. We focused on relationship between blood lymphocytes, ALS clinical subtype disease severity. Subjects Methods Blood samples were collected from 92 patients with sporadic 21 Primary (PLS) 37 affected by primary progressive multiple sclerosis (PPMS) inactive plaques. was taken controls at time...
10635 Background: Despite patient interest in knowing whether diet is linked to multiple myeloma (MM), there limited research on dietary patterns and MM risk (Malik et al. BCJ 2022). Two studies have assessed this risk, albeit with a small number of cases. The EPIC-Oxford cohort Oxford Vegetarian study (65 cases) showed that fish eaters, vegetarians vegans had significantly reduced compared meat eaters (Key AJCN 2014). Nurses’ Health Study Professionals Follow-up (478 increased men Empirical...
7526 Background: Dietary supplement usage is prevalent among cancer patients in the United States (US), estimated at 70% (Du et al., 2020). For with plasma cell disorders (PCDs), there a strong interest use. Our 23-question survey aims to understand perceptions, habits, and knowledge surrounding specific supplements — Vitamin D, omega-3 fatty acids, turmeric/curcumin, probiotics. Methods: From September 2023 January 2024, 480 responses were collected via HealthTree Cure Hub. Deidentified...
<h3>Background</h3> Poor diet quality lacking plant-based foods, elevated body mass index (BMI), insulin resistance, microbiome dysbiosis, as well inflammation have all been implicated in progression from monoclonal gammopathy of undetermined significance (MGUS) and smoldering multiple myeloma (SMM) to MM. Whether a dietary intervention can delay has not investigated. <h3>Methods</h3> We conducted pilot, single-arm trial providing high fiber plant based (HFPBD) for 12 weeks health coaching...
Despite patient interest in knowing whether diet is linked to multiple myeloma (MM), there limited research on dietary patterns and MM risk. Two studies have assessed this risk, albeit with a small number of cases. The EPIC-Oxford cohort Oxford Vegetarian study (65 cases) showed that fish eaters, vegetarians vegans had significantly reduced risk compared meat eaters. Nurses' Health Study Professionals Follow-up (478 increased men Empirical Dietary Inflammatory Pattern.