- Nanoparticles: synthesis and applications
- Polyoxometalates: Synthesis and Applications
- Healthcare and Environmental Waste Management
- Gold and Silver Nanoparticles Synthesis and Applications
- Probiotics and Fermented Foods
- Enzyme Production and Characterization
- Characterization and Applications of Magnetic Nanoparticles
- Medical and Biological Ozone Research
- Enzyme Catalysis and Immobilization
- Membrane-based Ion Separation Techniques
- Antimicrobial agents and applications
- Digestive system and related health
- Iron Metabolism and Disorders
- Nanoparticle-Based Drug Delivery
- Advanced Nanomaterials in Catalysis
- Nanotechnology research and applications
- Neurogenetic and Muscular Disorders Research
- MicroRNA in disease regulation
- Adenosine and Purinergic Signaling
- Diabetes and associated disorders
- Chemistry and Chemical Engineering
- Circular RNAs in diseases
- Biochemical and Structural Characterization
- Extracellular vesicles in disease
- SARS-CoV-2 detection and testing
National Institute of Chemical Physics and Biophysics
2016-2023
North Estonia Medical Centre
2022
Tallinn University of Technology
2018
University of Tartu
2014
HansaBioMed (Estonia)
2013
Bacterial infections are one of the leading causes death worldwide. In case topical bacterial such as wound infections, silver (Ag) has historically been most widely used antibacterials. However, scientific publications have demonstrated adverse effects on human cells, ecotoxicity and insufficient antibacterial effect for complete elimination infections. The use Ag in form nanoparticles (NPs, 1-100 nm) allows to control release ions but is still not sufficient eliminate infection avoid...
The activity of a new class antimicrobials-polyoxometalate ionic liquids (POM-ILs)-is systematically investigated. prototype POM-ILs feature Keggin-type anions (α-SiW11 O398- ) and tetraalkylammonium ions as active cationic species. Antimicrobial tests the against important human pathogens show that variation alkyl chain length cation leads to significant changes in antimicrobial medically relevant Gram-negative bacteria Escherichia coli Pseudomonas aeruginosa, especially Gram-positive...
Due to the high prevalence of infectious diseases and their concurrent outbreaks, there is a interest in developing novel materials with antimicrobial properties. Antibacterial antiviral properties range metal-based nanoparticles (NPs) are promising means fight airborne caused by viruses bacteria. The aim this study was test metals efficacy against three viruses, namely influenza A virus (H1N1; A/WSN/1933) coronaviruses TGEV SARS-CoV-2; two bacteria,
Abstract Clinical use of CuO nanoparticles (NPs) as antibacterials can be hampered by their toxicity to human cells. We hypothesized that certain surface functionalizations NPs may render toxic bacteria, but still relatively harmless To control this hypothesis, the differently functionalized bacteria Escherichia coli vs cells (THP-1 macrophages and HACAT keratinocytes) was compared using similar conditions end points. with polyethylene glycol (CuO–PEG), carboxyl (CuO–COOH, anionic), ammonium...
The intestinal microbiota is essential to the maturation and homeostasis of immune system. Immunoblot assays were used establish prevalence serum IgG, IgM, IgA antibodies specific for Bifidobacterium adolescentis , longum Lactobacillus rhamnosus GG proteins in young children presenting with or without type 1 diabetes (T1D). We demonstrated that between ages 6 12 months had a substantial increase frequency IgG L. proteins. measured class antibody reactivity against B. DSM 20083, 20086, 20088...
Nanoparticles with SiO2 coating were synthesized to have a cubic iron core. These found saturation magnetization very close the highest possible value of any iron-containing nanoparticles and bulk magnetization. The in vitro toxicology studies show that they are highly biocompatible possess better MRI contrast agent potential than oxide NPs.