Maria Elena Guerzoni
A5018581042- Hemoglobinopathies and Related Disorders
- Blood groups and transfusion
- Iron Metabolism and Disorders
- COVID-19 Clinical Research Studies
- Neurological Complications and Syndromes
- Glycogen Storage Diseases and Myoclonus
- Autopsy Techniques and Outcomes
- Forensic Anthropology and Bioarchaeology Studies
- Respiratory and Cough-Related Research
- Hepatitis C virus research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Orthodontics and Dentofacial Orthopedics
- Lysosomal Storage Disorders Research
- Female Genital Mutilation/Cutting Issues
- Evolutionary Psychology and Human Behavior
- Liver Disease and Transplantation
- Kawasaki Disease and Coronary Complications
- Spinal Dysraphism and Malformations
- Asthma and respiratory diseases
- Celiac Disease Research and Management
- Erythrocyte Function and Pathophysiology
- Child Nutrition and Feeding Issues
- Prenatal Screening and Diagnostics
- Pharmacological Effects and Toxicity Studies
- Coronary Artery Anomalies
University of Modena and Reggio Emilia
2017-2025
Azienda Ospedaliero-Universitaria di Modena
2013-2023
University of Milan
2013-2014
The number of patients with sickle cell disease (SCD) has increased in Italy the past decade due to immigration. In spite established efficacy hydroxyurea (HU) childhood, population-based data regarding its prescription and effectiveness come mainly from studies performed adults or outside Europe.The Hydroxyurea SCD: A Large Nation-wide Cohort Study was a retrospective cohort study adult pediatric SCD attending 32 centers. Pediatric are analyzed separately.Out 504 children followed 11...
Posterior reversible encephalopathy syndrome (PRES) is one of the most common neurological complications in hematology-oncology pediatric patients. Despite an increasingly recognized occurrence, no clear consensus exists regarding how best to manage syndrome, because cases PRES have reported single-case reports or small series. Aim this paper identify incidence, clinical features, management, and outcome a large series patients.The occurred twelve centers Italian Association Pediatric...
Abstract Background Sickle Cell Disease (SCD) is the most common genetic disease worldwide. Neurological events are among worrisome clinical complications of SCD and frequently accompanied by cognitive impairment. Intellectual function in may vary according to environmental factors. Immigrant children with increasing at a global level display specific health care needs. The aim our multicenter study was describe intellectual first generation African immigrants influence sociodemographic...
Summary Acute chest syndrome (ACS) is a frequent cause of hospitalization in sickle cell disease (SCD). Despite advances acute care, many settings still lack knowledge about ACS best practices. After the AIEOP Guidelines were published 2012, suggesting standardized management Italy, retrospective study was performed to assess diagnostic and therapeutic pathways children. From 2013 2018, 208 episodes presented by 122/583 kids 11 centres. 73 male, mean age 10.9 years, 85% African, 92% HbSS or...
Abstract Background Children with coronavirus disease-2019 (COVID-19) have a milder clinical course than adults. We describe the spectrum of cardiovascular manifestations during COVID-19 outbreak in Emilia-Romagna, Italy. Methods A cross-sectional multicenter study was performed, including all patients diagnosed Kawasaki disease (KD), myocarditis, and multisystem inflammatory syndrome children (MIS-C) from February to April 2020. KD were compared those before epidemic. Results KD: 8 (6/8...
Environmental factors seem to influence clinical manifestations of sickle cell disease (SCD), but few studies have shown consistent findings. We conducted a retrospective multicentric observational study investigate the environmental parameters on hospitalization for vaso-occlusive crises (VOC) or acute chest syndrome (ACS) in children with SCD.Hospital admissions were correlated daily meteorological and air-quality data obtained from Regional Agencies period 2011-2015. The effect different...
Background. Lysosomal acid alpha-glucosidase (GAA) deficiency, also known as Pompe disease, is an autosomal recessive disorder that leads to the accumulation of glycogen in lysosomes and cytoplasm, resulting tissue destruction. Infantile-onset GAA deficiency characterized by cardiomyopathy severe generalized hypotonia. Without treatment, most patients die within first two years life. The demonstration reduced activity, followed sequencing gene, confirms disease. currently treated with enzyme...
Although rare in children, severe asthma is responsible for a heavy burden on families and society.Being condition, every center follows only limited number of patients, there solid rationale setting up networks to collect data.We present first report clinical features diagnostic workup children adolescents with included the database Italian Pediatric Respiratory Society (Società Italiana per le Malattie Respiratorie Infantili -SIMRI).24 pediatric pulmonology allergology centers took part...
Background Despite several publications covering patients from multiple centers, no international registry covered all with red blood cell diseases (RBCD) affected by COVID-19. The ERN-EuroBloodNet's provided real-time registration of SARS-CoV-2 RBCD, promoting timely disease-specific knowledge sharing during the pandemic's early stages. Procedures study evaluated patient distribution, infection across different RBBDs, and severity risk factors similar healthcare systems, using data...