A5037901560- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Cancer Research and Treatments
- Gastrointestinal disorders and treatments
- Immunotherapy and Immune Responses
- Helicobacter pylori-related gastroenterology studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Colorectal Cancer Screening and Detection
- Cancer Cells and Metastasis
- Radiomics and Machine Learning in Medical Imaging
- Sarcoma Diagnosis and Treatment
- Vascular anomalies and interventions
- Surgical Sutures and Adhesives
- Intestinal and Peritoneal Adhesions
- Immune Cell Function and Interaction
- Central Venous Catheters and Hemodialysis
- Colorectal Cancer Surgical Treatments
- Neuroendocrine Tumor Research Advances
- Cancer Immunotherapy and Biomarkers
- 3D Printing in Biomedical Research
- Acupuncture Treatment Research Studies
- Ovarian cancer diagnosis and treatment
- Enhanced Recovery After Surgery
- Dialysis and Renal Disease Management
Daegu Catholic University Medical Center
2013-2025
Catholic University of Daegu
2014-2024
Creative Research Enterprises (United States)
2016
Daegu University
2012
It is difficult to obtain biopsies from gastrointestinal stromal tumors (GISTs) prior surgery because GISTs are submucoal tumors, despite being the most common nonepithelial neoplasms of tract. Unlike anatomic imaging techniques, PET-CT, which a molecular tool, can be useful technique for assessing tumor activity and predicting malignant potential certain tumors. Thus, we aimed evaluate usefulness PET-CT as pre-operative prognostic factor by analyzing correlation between existing...
Peutz-Jeghers syndrome (PJS), also known as periorificial lentiginosis, is a rare autosomal dominant inherited disease with an incidence of 1/200,000 live-borns. Mutations in the serine-threonine kinase 11 (STK11) gene are considered major cause PJS. The most frequent complication at young age recurrent intussusception due to multiple hamartomatous polyps, primarily small intestine. Although extremely rare, bowel should be fully examined certain additional intussusceptions not present....
The standard treatment for primary localized gastric gastrointestinal stromal tumor (GIST) is surgical resection. clinical behavior of GIST after resection extremely variable. We conducted a multicenter, retrospective study GISTs patients who underwent curative to evaluate features and the prognosis surgically treated GISTs.We performed on 406 consecutive resections at four university hospitals in Daegu, Korea, between March 1998 2012. retrospectively collected medical records were reviewed...
Postoperative ileus (POI) is a common problem after abdominal surgery. Acupuncture being accepted as an option for reducing POI and managing various functional gastrointestinal disorders. Therefore, this pilot study was conducted to evaluate the effect of acupuncture on duration other surgical outcomes in patients who underwent gastric surgery.A prospective, randomized, controlled cancer surgery from January 2013 December 2013. Ten were randomly assigned into (A) or nonacupuncture (NA)...
Peritoneal metastasis is the most frequent cause of death in patients with gastric cancer. Reverse transcriptase-polymerase chain reaction (RT-PCR) assay peritoneal washes has been used to predict carcinoma. We applied carcinoembryonic antigen (CEA) and melanoma-associated gene (MAGE) RT-PCR for detection carcinoma after curative surgery evaluated its clinical significance. were obtained from 117 MAGE A1–A6 CEA performed, results according their clinicopathologic characteristics. Three-year...
KLASS (the Korean Laparoendoscopic Gastrointestinal Surgery Study) is a time-honored study group that has established laparoscopic surgery for gastrointestinal disease in Korea and performed some important studies the rationale of surgery. A multi-center RCT (randomized controlled trial) to compare quality life (QOL) patients undergoing totally distal gastrectomy (TLDG) laparoscopy-assisted (LADG) gastric cancer, named as 07, been currently prepared Korea. Patients diagnosed with clinical...
A composite glandular/exocrine-endocrine carcinoma of the gastrointestinal tract is characterized by co-existence two adjacent, but histologically-distinct tumors in an organ. Composite carcinomas are a special type tumor comprised common adenocarcinomas and neuroendocrine components that account for at least one-third entire area. have been reported range organs, relatively rare stomach. We report case with adenocarcinoma stomach (mixed exocrine-endocrine carcinoma), which was misdiagnosed...
Lymphangioma is a benign form of neoplasm arising from the lymphatic system.It occurs as result congenital malformations lymphatics leading to obstruction local lymph flow and development lymphangiectasia.Lymphangiomas are common in pediatric patients, soft tissues neck axillae, but lymphangioma pancreas extremely rare, accounting for less than 1% these tumors.It more frequently females often located distal pancreas.Although cystic should be taken into consideration differential diagnosis...
Peritoneal recurrence is the most common cause of death after surgery for gastric cancer. Reverse transcriptase polymerase chain reaction (RT-PCR) analysis has been used to detect free cancer cells in peritoneal wash during surgery. This study was conducted evaluate prognostic significance carcinoembrionic antigen (CEA) mRNA detected by RT-PCR from patients with curative resection through a 5-year follow-up.Peritoneal were obtained 117 who underwent The association between CEA results,...
We validate the 7th American Joint Committee on Cancer/Union for International Cancer Control (AJCC/UICC) staging system gastric cancer and propose a new that reflects prognostic significances of each T N category.Methods: Data from 5,957 patients who underwent curative gastrectomies 2000 to 2007 at 4 university hospitals in Daegu Metropolitan city Korea were analyzed validation AJCC/UICC cancer.The hazard ratios respective categories estimated converted weightings summated make score...
Due to significant growth in the volume of information produced by cancer research, staying abreast recent developments has become a challenging task. Artificial intelligence (AI) can learn, reason, and understand enormous corpus literature available scientific community. However, large-scale studies comparing recommendations AI multidisciplinary team board (MTB) gastric treatment have rarely been performed. Therefore, retrospective real-world study was conducted assess level concordance...
The RT-PCR assay of peritoneal washes has been used to predict metastasis gastric carcinoma. We melanoma associated gene (MAGE) detect carcinoma after curative surgery and evaluated its clinical significance.Eighty-four 23 tumor normal tissues were obtained from 84 patients. MAGE A1-A6 was carried out, the results according their clinicopathologic characteristics. Five-year follow-up studies out periodically, overall survival rates retrospectively investigated using medical records.For...
A total of 76 blood samples from patients without malignant disease and 107 with were investigated for the presence circulating tumor cells (CTCs). To detect CTCs, hematopoietic removed different RNA extraction methods used to amplify melanoma antigen-encoding gene family member A1-family A6 (MAGE A1-6) human telomerase reverse transcriptase (hTERT) as potential CTC markers. Comparison between four extracting was performed. The enriched by cluster differentiation 45 (CD45) antibody...
<b><i>Background/Purpose:</i></b> Gastric gastrointestinal stromal tumors (GISTs) have a highly variable clinical course, and recurrent disease sometimes develops despite curative surgery. This study was undertaken to investigate the surgical role in treating gastric GISTs evaluate clinicopathological features of large series patients who underwent resection for clarify which were independent prognostic factors. <b><i>Methods:</i></b> The data...
To develop a new method for gastric cancer detection with juice using melanoma-associated gene (MAGE) RNA and pepsinogen (PG).In total, 183 paired serum specimens were obtained from 134 patients 49 healthy individuals. The analyzed MAGE A1 to A6 nested reverse transcription-polymerase chain reaction. PG measured I II immunoassay.The I/II ratios more accurate than those of serum. combination test the ratio was most accurate, sensitivity 77.6% specificity 87.8%. 78.8% stage not influenced by...
Abstract Aim The vascular endothelial growth factor ( VEGF ) or its family might play role in tumor‐related angiogenesis gastrointestinal stromal tumors GIST ), thereby affecting the prognosis. Accordingly, present study analyzed impact of and receptor‐2 VEGFR ‐2) gene polymorphisms on prognosis for patients. Methods In all, 213 consecutive patients with from five medical centers were enrolled study. genomic DNA was extracted paraffin‐embedded tumor tissue, four (−2578 C / A , −1498 T −634 G...
Background/Aim: The aim of this study was to detect circulating tumor cells (CTC) in the peripheral blood gastrointestinal cancer patients using conditionally reprogrammed cell (CRC) culture. Materials and Methods: We confirmed sensitivity CRC culture method. Five ml were obtained from 81 (56 colorectal 25 gastric). collected mononuclear cultured for 4 weeks condition. Finally, characterized by RT-PCR expression hTERT MAGE A1-6 mRNA. Results: method had a CTC detection limit 6 gastric cells....
Tegafur/gimeracil/oteracil (S-1) and capecitabine plus oxaliplatin (CAPOX) are standard adjuvant chemotherapies (ACs) administered after gastrectomy to patients with stage II or III gastric cancer. However, the efficacy of AC in elderly remains unclear. The objective this retrospective multicenter cohort study was compare efficacies S-1 CAPOX aged ≥70 years.Nine hundred eighty-three who were treated using (768 patients) (215 enrolled study. Each patient underwent curative for cancer at one...