Weiwei Chen

ORCID: 0000-0003-2048-8800
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About
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Research Areas
  • Plant Stress Responses and Tolerance
  • Smart Materials for Construction
  • Cardiomyopathy and Myosin Studies
  • Climate change and permafrost
  • High Entropy Alloys Studies
  • Environmental and Agricultural Sciences
  • Venous Thromboembolism Diagnosis and Management
  • Cardiac Fibrosis and Remodeling
  • Tribology and Lubrication Engineering
  • Ion channel regulation and function
  • Atrial Fibrillation Management and Outcomes
  • Soil and Unsaturated Flow
  • Cardiac Arrhythmias and Treatments
  • MicroRNA in disease regulation
  • Neuroscience and Neural Engineering
  • Congenital heart defects research
  • Plant Growth Enhancement Techniques
  • Cardiac electrophysiology and arrhythmias
  • Soil Carbon and Nitrogen Dynamics
  • Williams Syndrome Research
  • Calcium signaling and nucleotide metabolism
  • Polymer-Based Agricultural Enhancements
  • Anodic Oxide Films and Nanostructures
  • Piezoelectric Actuators and Control
  • Silicon Effects in Agriculture

Jilin University
2009-2025

Union Hospital
2018-2025

Beijing Institute of Technology
2024

Union Hospital
2018-2024

Wenzhou Medical University
2024

Ministry of Natural Resources
2023

Land Consolidation and Rehabilitation Center
2023

Shaanxi Provincial Land Engineering Construction Group
2023

China Land Surveying and Planning Institute
2023

Health Commission of Jilin Province
2018-2021

The progressive loss of cardiomyocytes caused by cell death leads to cardiac dysfunction and heart failure (HF). Rapamycin has been shown be cardioprotective in pressure‑overloaded ischemic diseases regulating the mechanistic target rapamycin (mTOR) signaling network. However, impact on cardiomyocyte chronic HF remains undetermined. Therefore, current study we addressed this issue using a rat myocardial infarction (MI)‑induced model induced ligating coronary artery. Following surgery, rats...

10.3892/ijmm.2019.4407 article EN cc-by-nc-nd International Journal of Molecular Medicine 2019-11-13

Potassium ion transport across myocardial cell membrane is essential for type 2 long QT syndrome (LQT2). However, the dysfunction of potassium due to genetic mutations limits therapeutic effect in treating LQT2. Biomimetic channels that selectively and efficiently ions cellular membranes are promising treatment To corroborate this, we synthesized a series foldamer-based with different side chains, found biomimetic channel K+ (BICK) highest activity among them. The selected BICK can restore...

10.1016/j.actbio.2024.04.046 article EN cc-by-nc-nd Acta Biomaterialia 2024-05-03

ABSTRACT Background Arterial calcification and its associated major adverse cardiovascular events (MACEs) are significant contributors to rehospitalization poor clinical outcomes. This study aims evaluate the diagnostic utility of miR‐126‐3p miR‐145‐5p in detecting arterial calcification, as well their prognostic value predicting occurrence MACEs. Methods A total 131 patients who underwent coronary artery intervention intravascular imaging were enrolled. Among them, 88 diagnosed with while...

10.1002/ccd.31616 article EN Catheterization and Cardiovascular Interventions 2025-05-20

Factor Xa (FXa) not only plays an active role in the coagulation cascade but also exerts non-hemostatic signaling through protease-activated receptors (PARs). This study aimed to investigate whether FXa inhibitor, Rivaroxaban (RIV), attenuates adverse cardiac remodeling rats with myocardial infarction (MI) and identify underlying molecular mechanisms it uses.An MI model was induced eight-week-old, male Wistar rats, by permanent ligation of left anterior descending coronary artery. were...

10.7717/peerj.16097 article EN cc-by PeerJ 2023-09-27

Freeze–thaw (FT) in northern China is a common event spring and autumn, the release of sulfur dioxide from coal-burning winter apt to trigger acid precipitation. Both these stresses can aggravate wintering ability white clover (Trifolium repens L.). Acid precipitation FT simulation experiments were carried out field an indoor alternation refrigerator, respectively. The contents soluble protein, sugar, malondialdehyde (MDA), proline antioxidant activity tested under stress. results showed...

10.1071/fp19072 article EN Functional Plant Biology 2019-12-09

10.1007/s00128-016-1982-5 article EN Bulletin of Environmental Contamination and Toxicology 2016-12-01

Circulating microRNAs (miRNAs) have been proposed as potential biomarkers for left ventricular remodeling in postinfarction heart failure (HF). However, the diagnostic reproducibility of use circulating miRNAs may be affected by temporal expression following myocardial infarction (MI). In current study, using a MI-induced HF rat cohort (4-, 8-, and 12-week post-MI groups), we investigated plasma during development remodeling. The miRNA profile was obtained sequencing. candidate tissues...

10.1155/2019/5093803 article EN Disease Markers 2019-12-02

Objective This study aimed to investigate whether differential expression of the retinoic acid receptor-related orphan receptor A ( RORA) gene is related occurrence acute myocardial infarction (AMI). Methods was a retrospective study. White blood cells 93 patients with and 74 stable coronary artery disease were collected. Reverse transcription quantitative polymerase chain reaction western blotting used measure RORA mRNA protein expression, respectively. Results levels in peripheral...

10.1177/03000605211019663 article EN cc-by-nc Journal of International Medical Research 2021-06-01

Since conventional electro-Fenton still suffers from low Fe2+ conversion efficiency, the use of efficient and durable non-homogeneous cathode light to construct a photo-electro-Fenton system for pollutant degradation has attracted extensive research. In this study, Fe3O4@Carbon felt (CF) electrodes were created using hot-melt synthesis method, series tests investigate chemical physical properties materials, as well their electrochemical properties. The Fe3O4@CF electrode was utilized degrade...

10.2139/ssrn.4366475 article EN 2023-01-01

Trans‑radial access for percutaneous coronary intervention or angiography has gained popularity amongst interventional cardiologists. Radial is also thought to reduce the incidence of acute kidney injury (AKI) in immediate post‑operative period. The purpose present study was perform a comprehensive updated systematic review and meta‑analysis comparing AKI following radial vs. femoral route catheterization. An electronic literature search PubMed, BioMed Central, Scopus, Cochrane Central...

10.3892/etm.2020.9170 article EN Experimental and Therapeutic Medicine 2020-09-02

Abstract Background Due to its low incidence and diverse manifestations, paradoxical embolism (PDE) is still under-reported not routinely considered in differential diagnoses. Concomitant acute myocardial infarction (AMI) pulmonary (PE) caused by PDE has rarely been reported. Case presentation A 45-year-old woman presented with chest pain difficulty breathing. Multiple imaging modules including ECG, echocardiography, emergency cardioangiogram (CAG), CT angiography of the arteries showed...

10.1186/s12872-021-02123-1 article EN cc-by BMC Cardiovascular Disorders 2021-06-24

Multi-degrees of freedom piezo-driven precision positioning platforms with large working strokes are demanded in many research fields. Although multi-degrees have been proposed, few them can achieve both stroke and high speed, which hinders their applications. In this study, a two-degrees platform was proposed by stacking two identical stick-slip piezoelectric actuators. To simplify the practical implementation stroke, actuator employed special structure, compliant mechanism slider were...

10.1063/5.0106657 article EN Review of Scientific Instruments 2022-10-01
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