A5012786711- biodegradable polymer synthesis and properties
- Advanced Polymer Synthesis and Characterization
- Electrospun Nanofibers in Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Hydrogels: synthesis, properties, applications
- Bone Tissue Engineering Materials
- Polymer Surface Interaction Studies
- Carbon dioxide utilization in catalysis
- 3D Printing in Biomedical Research
- Graphene and Nanomaterials Applications
- Supramolecular Self-Assembly in Materials
- Antimicrobial agents and applications
- Additive Manufacturing and 3D Printing Technologies
- Wound Healing and Treatments
- Crystallization and Solubility Studies
- Advanced Drug Delivery Systems
- Surfactants and Colloidal Systems
- Tissue Engineering and Regenerative Medicine
- Nanoplatforms for cancer theranostics
- Dendrimers and Hyperbranched Polymers
- Photopolymerization techniques and applications
- Luminescence and Fluorescent Materials
- Advanced Sensor and Energy Harvesting Materials
- Synthesis and properties of polymers
- Protein purification and stability
East China University of Science and Technology
2016-2025
XinHua Hospital
2012-2024
Shanghai Jiao Tong University
2012-2024
Ministry of Education of the People's Republic of China
2012
Fudan University
2009
University of Michigan
2002-2003
Cornell University
2001-2002
Chinese Academy of Sciences
1999
Jilin University
1997-1998
Institute of Chemistry
1997
Abstract A novel kind of rattle‐type hollow magnetic mesoporous sphere (HMMS) with Fe 3 O 4 particles encapsulated in the cores silica microspheres has been successfully fabricated by sol–gel reactions on hematite followed cavity generation hydrothermal treatment and H 2 reduction. Such a structure merits both enhanced drug‐loading capacity significant magnetization strength. The prepared HMMSs realize relatively high storage up to 302 mg g −1 when ibuprofen is used as model drug, IBU–HMMS...
Excessive scar formation has adverse physiological and psychological effects on patients; therefore, a therapeutic strategy for rapid wound healing reduced is urgently needed. Herein, bilayered thiolated alginate/PEG diacrylate (BSSPD) hydrogels were fabricated sequential release of small extracellular vesicles (sEVs), which acted in different phases, to achieve scarless healing. The sEVs secreted by bone marrow derived mesenchymal stem cells (B-sEVs) released from the lower layer promote...
A method for the production of crystalline polymorphs from solution is described which utilizes a diverse set polymer heteronuclei. Application to polymorph selection important pharmaceuticals acetaminophen and carbamazepine demonstrated. This provides new paradigm selection, where solvent temperature conditions can be chosen on basis process considerations heteronucleus varied specific production.
A facile hard-templating route has been successfully developed to fabricate uniform hollow mesoporous silica spheres and ellipsoids by using hematite as hard template. The outer diameter of the spherical particles can be well adjusted in a sub-micrometric range (typically around 100–200nm) selecting suitable core templates. thickness shell tuned independently at 10nm tailoring amount tetraethoxysilane n-octadecyltrimethoxysilane mixture. Ellipsoidal are prepared for first time when spindle...
This study aimed to optimize poly(ethylene glycol)-b-poly(ε-caprolactone) (PEG-b-PCL)-based amphiphilic block copolymers for achieving a better micellar drug delivery system (DDS) with improved solubilization and of doxorubicin (DOX). First, the Flory-Huggins interaction parameters between DOX core-forming segments [i.e., poly(ε-caprolactone) (PCL) poly[(ε-caprolactone-co-γ-(carbamic acid benzyl ester)-ε-caprolactone] (P(CL-co-CABCL))] was calculated assess drug-polymer compatibility. The...
Abstract Graphene nanosheets offer intriguing electronic, thermal and mechanical properties are expected to find a variety of applications in high‐performance nanocomposite materials. The great challenge exfoliating dispersing pristine graphite or graphene sheets various solvents matrices can be achieved by facilely properly chemical functionalization the carbon nanosheets. Here we reported an efficient way functionalize with presynthesized polymer via combination atom transfer nitroxide...
Polymer-functionalized graphene sheets play an important role in graphene-containing composite materials. Herein, functionalized covalently linked with radical polymer, graphene-graft-poly(2,2,6,6-tetramethylpiperidin-1-oxyl-4-yl methacrylate) (G-g-PTMA), were prepared via surface-initiated atom transfer polymerization (SI-ATRP). A cathode G-g-PTMA as major active material and reduced oxide (RGO) conductive additive was fabricated a simple dispersing–depositing process, this exhibited...
Abstract Glutathione (GSH) depletion‐induced ferroptosis has emerged as a promising treatment for malignant cancer. It works by inactivating glutathione peroxidase 4 (GPX4) and facilitating lipid peroxidation. However, effectively delivering inducers depleting intracellular GSH remains challenging due to the short half‐lives high hydrophobicity of small‐molecule inducers. These often require additional carriers. Herein, diselenide‐containing polymers can consume induce pancreatic cancer...
Diagnostic and therapeutic illumination on internal organs tissues with high controllability adaptability in terms of spectrum, area, depth, intensity remains a major challenge. Here, we present flexible, biodegradable photonic device called iCarP micrometer scale air gap between refractive polyester patch the embedded removable tapered optical fiber. ICarP combines advantages light diffraction by fiber, dual refractions gap, reflection inside to obtain bulb-like illumination, guiding...
Abstract A mild and efficient strategy is presented for growing thermo‐sensitive polymers directly from the surface of exfoliated graphene oxide (GO). This method involves covalent attachment Br‐containing initiating groups onto GO sheets followed by in situ poly[poly(ethylene glycol) ethyl ether methacrylate] (PPEGEEMA) via single‐electron‐transfer living radical polymerization (SET‐LRP). Considering lack reactive functional on GO, were subjected to an epoxide ring opening reaction with...
Targeted drug delivery systems, especially those that use nanoparticles, have been the focus of research into cancer therapy during last decade, to improve bioavailability and anticancer drugs specific tumor sites, thereby reducing toxicity side effects normal tissues. However, positive antitumor these nanocarriers observed in conventional monolayer cultures frequently fail vivo, due lack physical biological barriers resembling seen actual body. Therefore, collagen-based 3-D multicellular...