A5053980791- Botulinum Toxin and Related Neurological Disorders
- RNA regulation and disease
- Parkinson's Disease Mechanisms and Treatments
- Glaucoma and retinal disorders
- Foreign Body Medical Cases
- Polyomavirus and related diseases
- Multiple Sclerosis Research Studies
- Cardiovascular Syncope and Autonomic Disorders
- Airway Management and Intubation Techniques
- Migration, Identity, and Health
- Neurological disorders and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Intraocular Surgery and Lenses
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Immunotherapy and Immune Responses
- Impact of Technology on Adolescents
- Intracerebral and Subarachnoid Hemorrhage Research
- Peripheral Neuropathies and Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Myasthenia Gravis and Thymoma
- Female Genital Mutilation/Cutting Issues
- Urologic and reproductive health conditions
- Testicular diseases and treatments
- Fibromyalgia and Chronic Fatigue Syndrome Research
Mapúa University
2024
University Medical Center Groningen
2024
Sorbonne Université
2020-2023
Centre National de la Recherche Scientifique
2023
Institut du Cerveau
2023
Inserm
2023
Fondation de Rothschild
2021
Hôpital Saint-Antoine
2020
Assistance Publique – Hôpitaux de Paris
2020
Hôpital Foch
2017-2019
To determine the prognostic value of persisting neuroinflammation in multiple sclerosis (MS) lesions, we developed a 18 kDa-translocator-protein-positron emission tomography (PET) -based classification each lesion according to innate immune cell content and localization. We assessed respective predictive phenotype diffuse inflammation on atrophy disability progression over 2 years.Thirty-six people with MS (disease duration 9 ± 6 years; 12 relapsing-remitting, 13 secondary-progressive, 11...
Background and Purpose— Parenchymal hematoma (PH) is a rare but dreadful complication of acute ischemic stroke with unclear underlying mechanisms. We aimed to study the incidence predictors PH after mechanical thrombectomy. Methods— Data from prospective observational multicenter registry was screened identify patients an anterior circulation large vessel occlusion who underwent Clinical, imaging, procedural characteristics were used for analysis, including brain imaging systematically...
Background: Progressive multifocal leukoencephalopathy (PML) among multiple sclerosis (MS) patients receiving dimethyl fumarate (DMF) is associated with iatrogenic lymphopenia, predominating on CD8+ T-cells. Objectives and Methods: We report an unusual case of DMF-related PML in a 66-year-old MS patient preserved lymphocyte count (nadir: 810/mm 3 ) normal T-cells count. Results: A massive overexpression the inhibitory receptor Programmed Cell Death 1 (PD-1) memory effector together impaired...
Positron emission tomography with18kDa-translocator (TSPO) tracers opens the perspective to image innate immune cells underlying smoldering component of multiple sclerosis (MS), that currently mostly escape from MRI evaluation. Using [18F]-DPA-714-PET, we developed a novel lesion TSPO based classification MS lesions and showed an unexpectedly high proportion have persistent neuroinflammatory content. A longitudinal follow up subjects unraveled this lesional predicted atrophy clinical...
Middle-aged persons living with HIV (PLHIV) have a heightened risk of more concomitant age-related comorbidities that are acknowledged as signs poorer prognosis after deep-brain stimulation the subthalamic nucleus (STN-DBS) at younger-than-expected ages. To assess beneficial and adverse effects STN-DBS in PLHIV Parkinson's disease (PD).We retrospectively included nine PD who had sustained virological control. Patients were followed up for 7 ± 4 years.Patients' mean ages onset 45 15 53 16...