A5100771600- Colorectal Cancer Surgical Treatments
- 3D Printing in Biomedical Research
- Cancer-related molecular mechanisms research
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal cell carcinoma treatment
- Ocular Diseases and Behçet’s Syndrome
- Endodontics and Root Canal Treatments
- Diverticular Disease and Complications
- Colorectal and Anal Carcinomas
- Circular RNAs in diseases
- Oral microbiology and periodontitis research
- Tissue Engineering and Regenerative Medicine
- Ferroptosis and cancer prognosis
- Infectious Diseases and Tuberculosis
- Cancer-related gene regulation
- Signaling Pathways in Disease
- Hematopoietic Stem Cell Transplantation
- Electrohydrodynamics and Fluid Dynamics
- Inflammatory mediators and NSAID effects
- Dental Implant Techniques and Outcomes
- Multiple and Secondary Primary Cancers
- Management of metastatic bone disease
- Anorectal Disease Treatments and Outcomes
- Peptidase Inhibition and Analysis
- Pancreatic and Hepatic Oncology Research
Sun Yat-sen University
2007-2025
Eighth Affiliated Hospital of Sun Yat-sen University
2023-2025
Sun Yat-sen Memorial Hospital
2021-2025
Shandong University of Traditional Chinese Medicine
2024
Weatherford College
2023
The First People's Hospital of Tianmen
2023
Wangjing Hospital of China Academy of Chinese Medical Sciences
2022
Shandong First Medical University
2013-2022
Shandong Tumor Hospital
2013-2022
Yangzhou University
2022
Robot-assisted versus conventional laparoscopic operation in anus-preserving rectal cancer: a meta-analysis Yongzhen Cui,1,2,* Cheng Li,3,* Zhongfa Xu,4 Yingming Wang,1,2 Yamei Sun,5 Huirong Xu,1 Zengjun Li,1 Yanlai Sun1 1Department of Gastrointestinal Cancer Surgery, Shandong Hospital Affiliated to University, Academy Medical Sciences, 2School Medicine and Life University Jinan-Shandong 3Department President’s Office, 4Department The Jinan, 5Department Clinical Laboratory, Zhucheng...
Peri-implantitis is a plaque-associated pathological condition occurring in tissues around dental implants, characterized by inflammation the peri-implant mucosa and subsequent progressive loss of supporting bone. Wnt5a activating ligand non-canonical Wnt signaling pathways plays important roles leukocyte infiltration cytokine/ chemokine production inflammatory disorders. Previous studies showed that was significantly up-regulated gingival chronic aggressive periodontitis. However,...
Dietary phosphorus intake may serve as a potential predictor for peripheral neuropathy (PN). While past research has predominantly focused on the relationship between dietary and bone health, relatively little is known about its role in nervous system, particularly association with PN.
This study aims to detect Mycobacterium tuberculosis complex (MTBC) DNA in intraocular fluid from clinically suspected tuberculous uveitis patients using multiplex polymerase chain reaction (PCR) and investigate the diagnostic utility of PCR for uveitis. Primers targeting three specific genes (MPB64, CYP141, IS6110) within MTBC genome were designed. Multiplex was conducted H37Rv strain as well extracted fluids confirmed assess primer specificity method feasibility. Intraocular samples...
Objective: To evaluate the effectiveness and safety of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in children with stage 4/M neuroblastoma (NB). Methods: This study was a prospective, single-arm, multicenter clinical trial conducted by Sun Yat-sen Memorial Hospital, Children's Hospital Nanjing Medical University, Zhejiang University School Medicine, First Affiliated Guangxi Xinhua to Shanghai Jiao Tong Medicine. From March 1, 2019 August 31, 2023, 25 confirmed NB received...
Organ manufacturing is a promising method to replace failing complex organs. In this study, new cell cryopreservation technique was developed with cryoprotectants being directly incorporated into the cell/hydrogel construct according predesigned structures and then subjected special freezing/thaw process. The hydration of gelatin/alginate hydrogel greatly increased while eutectic temperature decreased by adding glycerol. addition dextran-40 found also effectively improve survival when most...
Abstract Background Ocular tuberculosis is a relatively rare extrapulmonary manifestation of tuberculosis. This vision-threatening disease extremely challenging to diagnose, particularly because it can mimic other diseases. We report case tuberculous ciliary body granuloma initially diagnosed as bullous retinal detachment. Case A 52-year-old female presented with detachment in her left eye, and ultrasound biomicroscopy (UBM) verified the presence lesion granulomatous inflammation. The T-SPOT...
Abstract Background YangshenDingzhi granules (YSDZ) are clinically effective in preventing and treating COVID‐19. The present study elucidates the underlying mechanism of YSDZ intervention viral pneumonia by employing serum pharmacochemistry network pharmacology. Methods chemical constituents blood were examined using ultra‐performance liquid chromatography‐quadrupole/orbitrap high‐resolution mass spectrometry (UPLC‐Q‐Exactive Orbitrap MS). Potential protein targets obtained from...
Leukocyte immunoglobulin-like receptor B2 (LILRB2) has recently been considered a promising tumor promoter in human cancers.In this study, the expression of LILRB2 was assessed 82 samples surgically resected hepatocellular carcinoma (HCC) tissues using immunohistochemistry (IHC).LILRB2 overexpressed HCC and its positively significantly correlated with poor prognostic features patients, including cell differentiation, larger primary size, shorter overall survival. In addition, there positive...
Abstract Background To analyze and compare the characteristics of macular morphology microcirculation in diabetic edema (DME) patients with without serous retinal detachment (SRD). Methods One hundred eyes 81 diagnosed DME (the central thickness (CMT) ≥ 300 μm) from March 2020 to November were selected. According whether complicated SRD, divided into SRD (60 eyes) (40 groups. We analyzed following parameters: CMT, (CRT), subfoveal choroidal (SFCT), number hyperreflective foci (HF) complete...
Birth asphyxia causes hypoxia or inadequate perfusion to the organs of newborns, leading metabolism dysfunctions including blood glucose disorders.Neonates with and without birth were retrospectively recruited from 53 hospitals in Hubei Province January 1 December 31, 2018. In summary, 875, 1139, 180 cases control group, mild severe group recruited, respectively. Neonatal values at postnatal 1, 2, 6, 12 h (time error within 0.5 was allowed) gathered medical records.The incidence rates...
Gallbladder carcinoma (GC) is an extremely malignant gastrointestinal tumor, but relevant mechanisms are still under investigation. MicroRNA (miR) differentially expressed in a variety of tumors. Here we explored miR-204 patients with GC and related mechanisms. A GSE104165 chip was downloaded from the gene expression omnibus (GEO) for analysis. The qRT-PCR assay used quantifying Notch2 serum tissues patients, were followed up 3 years to analyze independent factors prognosis. CCK8, transwell,...
Dental peri-implantitis, which can be caused by several different microbial factors, is characterized inflammatory lesions of the surrounding hard and soft tissues an oral implant. Matrix Metalloproteinase 9 (MMP9) thought to involved in pathogenesis peri-implantitis. However, regulatory mechanism MMP9 peri-implantitis has not been fully elucidated. In this study, we tried evaluate peri-implantitis.We collected Peri-Implant Crevicular Fluid (PICF) from ten healthy implants periimplantitis...
HMGB1 is an important mediator of inflammation during ischemia-reperfusion injury on organs. The serum expression was increased significantly the 1st day after TACE and decreased which lower 30th TACE. Tumor markers post-DEB-TACE significantly. correlational analysis showed that patients with low had risks fever liver compared those higher expression, while ORR relatively worse. Patients longer PFS, better efficacy, quality life. With high post-expression, incidence too. There no statistical...