A5100629232- Rheumatoid Arthritis Research and Therapies
- Autoimmune and Inflammatory Disorders Research
- Spondyloarthritis Studies and Treatments
- Cell Adhesion Molecules Research
- Gout, Hyperuricemia, Uric Acid
- Acute Myeloid Leukemia Research
- Monoclonal and Polyclonal Antibodies Research
- Disaster Response and Management
- Advanced Proteomics Techniques and Applications
- Asthma and respiratory diseases
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Virus-based gene therapy research
- Healthcare Systems and Reforms
- Tracheal and airway disorders
- Photosynthetic Processes and Mechanisms
- Hepatitis B Virus Studies
- Optimism, Hope, and Well-being
- Neonatal Respiratory Health Research
- Light effects on plants
- Neuroblastoma Research and Treatments
- Hepatitis Viruses Studies and Epidemiology
- RNA Interference and Gene Delivery
- Hematopoietic Stem Cell Transplantation
- Liver Disease and Transplantation
- Acute Kidney Injury Research
Sichuan University
2014-2025
West China Hospital of Sichuan University
2017-2025
United States Food and Drug Administration
2022-2025
Food and Drug Administration
2025
Nanjing Medical University
2025
Zunyi Medical University
2023-2024
Hospital of Stomatology, Sun Yat-sen University
2024
Sun Yat-sen University
2010-2024
Xiamen University
2020-2024
Stomatology Hospital
2024
Abstract Introduction We examined the relationship between current tobacco use and functionally important respiratory symptoms. Methods Longitudinal cohort study of 16 295 US adults without COPD in Waves 2–3 (W2–3, 2014–2016) Population Assessment Tobacco Health Study. Exposure—Ten mutually exclusive categories including single product, multiple former, never (reference). Outcome—Seven questions assessing wheezing/cough were summed to create a symptom index; cutoffs ≥2 ≥3 associated with...
Sini decoction is a well-known formula of traditional Chinese medicine, which has been used to treat cardiovascular disease for many years. Previously, we demonstrated that prevented doxorubicin-induced heart failure in vivo. However, its active components are still unclear. Thus, investigated the and their cardioprotective mechanisms vitro neonatal rat cardiomyocytes H9c2 cell line models cytotoxicity. Our results treatment with higenamine or [6]-gingerol increased viability...
HEV ORF2 antigen (Ag) in serum has become a tool for diagnosing current infection. Particularly, urinary shedding of Ag been gaining increasing interest. We aim to uncover the origin, antigenicity, diagnostic performance, and significance urine infection.Clinical samples from patients with acute chronic infection were analyzed their levels. was by biochemical proteomic approaches. The origin kinetics during investigated mouse rabbit models, respectively. found that both level sensitivity...
Dietary phosphorus intake may serve as a potential predictor for peripheral neuropathy (PN). While past research has predominantly focused on the relationship between dietary and bone health, relatively little is known about its role in nervous system, particularly association with PN.
There is increasing evidence that starvation induces autophagy, which may be protective during starvation, in an AMPK-dependent manner. Polysaccharides from Fuzi (FPS) reportedly have effects on nutrition-limited livers. The present study was designed to determine whether FPS protected H9c2 cells against starvation-induced cytotoxicity using AMPK/mTOR-dependent mechanism. were incubated serum and glucose media for 12 hours establish a cell injury model. 3-Methyladenine (3MA, autophagy...
Abstract The psychological impact of a mudslide on survivors the Wenchuan earthquake in C hina and risk factors for development disaster‐related post‐traumatic stress disorder ( PTSD ) were investigated. study design was cross‐sectional included 1321 who had endured both an mudslide. Participants filled out self‐report questionnaire. One month after mudslide, rate symptoms 18.7%. Females, elderly, those with lower educational levels, that lacked social support, did not take precautionary...
Patient education is recommended as an integral part of disease management in ankylosing spondylitis (AS), a chronic rheumatic that predominantly affects young males and requires long-term management. Convenient cost-effective approaches to deliver patient are required these patients.This study aimed examine the effects theory-based educational intervention delivered through social networking app, WeChat, on knowledge, self-efficacy, exercise adherence, health outcomes Chinese AS was...
In patients with gout, suboptimal management refers to a lack of disease knowledge, low treatment compliance, and inadequate control serum uric acid (SUA) levels. Several studies have shown that continuous care is recommended for in gout. However, China, the model commonly used gout requires significant labor time costs, its efficiency coverage remain low. Mobile health (mHealth) may be able address these issues.
In plants, the conserved plant-specific photoreceptor UV RESISTANCE LOCUS 8 (UVR8) perceives ultraviolet-B (UV-B) light and mediates UV-B-induced photomorphogenesis stress acclimation. this study, we reveal that UV-B treatment shortens seedlings, increases stem thickness, enhances tolerance in rice (Oryza sativa) via its two photoreceptors OsUVR8a OsUVR8b. Although Arabidopsis (Arabidopsis thaliana) UVR8 (AtUVR8) all form monomers response to light, OsUVR8a, OsUVR8b function is only...
Gout is a common, chronic inflammatory joint disease, and men are more likely to suffer from gout. Improving patient self-management behaviors priority in gout healthcare. Psychological capital associated with diseases can be improved through number of interventions. However, this topic has not been well studied patients. The aim study was determine the level psychological among male patients Southwest China compare differences different levels capital. This cross-sectional study. A total...
Abstract Background Ankylosing spondylitis (AS), as a common inflammatory rheumatic disease, often causes depression and impaired health-related quality of life (QoL). Although positive effects patient education have been demonstrated, limited studies explored the benefits via mobile applications for AS patients. This study aimed to evaluate WeChat-based educational intervention on depression, QoL, other clinical outcomes in Methods We conducted single-blind randomized controlled trial from...
Abstract One of the characteristics leukemia is that it contains multiple rearrangements signal transduction genes and overexpression non-mutant genes, such as transcription factors. As an important regulator hematopoietic stem cell development erythropoiesis, LMO2 considered effective carcinogenic driver in T lines a marker poor prognosis patients with AML normal karyotype. LDB1 key factor transformation thymocytes into T-ALL induced by LMO2, enhances stability related proteins leukemia....
Abstract There are limited published studies on patient activation among patients with systemic lupus erythematosus (SLE) in China. Disease activity can significantly influence a patient's perception of their condition, subsequently impacting activation. However, the mechanisms through which disease influences remain poorly understood. This study aimed to investigate SLE China and explore influencing factors. We conducted cross-sectional from June December 2021 at rheumatology immunology...
The Human Variome Project (HVP) is an international consortium of clinicians, geneticists, and researchers from over 30 countries, aiming to facilitate the establishment maintenance standards, systems, infrastructure for worldwide collection sharing all genetic variations effecting human disease. HVP-China Node will build new supplement existing databases diseases. As first effort, we have created a novel variant database BRCA1 BRCA2, mismatch repair genes (MMR), APC breast cancer, Lynch...
The purpose of this study is to validate the seven-item wheezing module from International Study Asthma and Allergies in Children (ISAAC) nationally representative Population Assessment Tobacco Health Study. Adult participants with complete Wave 2-3 data were selected, including those asthma but excluding COPD other respiratory diseases (
In this study, we explored the predictors of quality life and depressive features in older people living temporary housing 13 months after Wenchuan earthquake western China. Anonymous data were collected via questionnaires a cross-sectional survey 189 earthquake. To explore outcomes interest, Pearson correlation multiple linear regression analysis used. The results indicated that interests/hobbies, subjective support, family function positive life, whereas instrumental activities daily...
Self-management behaviours can be crucial to improving disease symptoms and health outcomes in rheumatoid arthritis (RA) patients. Currently, the tools available for measuring self-management RA patients are either generalized with chronic diseases, which lack specificity or have poor reliability only specific scale-self-care scale (SCBS). The aim of this study was develop a evaluate its psychometric properties.The included two steps: development evaluation. items were developed from...
PurposeTo comprehensively understand the effects of intra-operative infusion magnesium sulfate on patients who underwent orthognathic surgery, including remifentanil consumption, postoperative pain, nausea and vomiting (PONV), inflammatory response, serum levels.MethodsSeventy-five adult undergoing surgery under general balanced anesthesia were randomly divided into two groups. One group (Group M) received 50 mg/kg in 20mL 0.9% saline after intubation, followed by a continuous at rate...