A5084906028- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Uterine Myomas and Treatments
- Endometrial and Cervical Cancer Treatments
- Pregnancy-related medical research
- Ethics in Clinical Research
- Menstrual Health and Disorders
- Cancer Genomics and Diagnostics
- Gynecological conditions and treatments
- Biomedical Ethics and Regulation
- Resilience and Mental Health
- Global Cancer Incidence and Screening
- Posttraumatic Stress Disorder Research
- Genetic factors in colorectal cancer
- Breast Cancer Treatment Studies
- Cancer survivorship and care
- Estrogen and related hormone effects
- Health, psychology, and well-being
- Colorectal Cancer Treatments and Studies
- Kruppel-like factors research
- Microbial metabolism and enzyme function
- Cancer, Stress, Anesthesia, and Immune Response
- Cancer Risks and Factors
- Childhood Cancer Survivors' Quality of Life
- Galectins and Cancer Biology
Institute of Research and Innovation Parc Tauli
2025
Universitat Autònoma de Barcelona
2025
Corporació Sanitària Parc Taulí
2025
Ponce Health Sciences University
2016-2025
Universidade Federal do Rio Grande
2025
Office of Basic Energy Sciences
2018-2024
Moffitt Cancer Center
2024
Universidad Señor de Sipán
2024
Albert Einstein College of Medicine
2024
Stony Brook University
2024
ObjectiveTo harmonize standard operating procedures (SOPs) and standardize the recording of associated data for collection, processing, storage human tissues relevant to endometriosis.DesignAn international collaboration involving 34 clinical/academic centers three industry collaborators from 16 countries on five continents.SettingIn 2013, two workshops were conducted followed by global consultation, bringing together 54 leaders in endometriosis research sample processing around...
Abstract In endometriosis, the increased survival potential of shed endometrial cells (which normally undergo anoikis) is suggested to promote lesion development. One mechanism that may alter anoikis autophagy. Using an autophagic flux inhibitor hydroxychloroquine (HCQ), we identified it reduces in vitro capacity human endometriotic and T-HESC cells. We also HCQ could decrease numbers disrupt histopathology, as well increase levels peritoneal macrophages IP-10 (10 kDa interferon- γ -induced...
Purpose: Endometriosis is a hormone-dependent, inflammatory, painful condition affecting 1 in 10 women during their reproductive years. The symptoms of endometriosis—dysmenorrhea, dyspareunia, infertility—negatively impact the quality life (QoL) affected women. Few studies have been conducted on mental health and QoL younger endometriosis patient population (adolescents young women). This study quantitative, cross-sectional was designed to address this gap by ascertaining whether coping...
Ovarian cancer is a leading cause of death in women the United States. While majority ovarian cancers are serous, some rarer subtypes (i.e. clear cell) often associated with endometriosis, benign gynecological disease. Iron rich cyst fluid endometriosis-associated and induces persistent oxidative stress. The role iron, an essential nutrient involved multiple cellular functions, normal cell survival remains unclear. Iron, presented as ferric ammonium citrate (FAC), dramatically inhibits types...
Background:Endometriosis is an inflammatory disease that defined by growth of endometrial tissue outside the uterus, resulting in pain, infertility, and emotional distress.Previous studies have shown HPA axis compromised patients with chronic, painful diseases, including endometriosis.However, underlying mechanisms physiological consequences dysfunctions these are largely unknown.We aimed to understand whether diurnal circulating cortisol levels women endometriosis affected how this impacts...
Most available therapies for endometriosis are hormone-based and generally broadly used without taking into consideration the ovarian hormone receptor expression status. This contrasts strikingly with standard of care other conditions such as breast cancer. We therefore aimed to characterize steroid receptors estrogen alpha (ESR1), beta (ESR2), progesterone (PGR) in different types endometriotic lesions eutopic endometrium from women controls using a tissue microarray (TMA). Nuclear levels...
High levels of inflammatory factors including chemokines have been reported in peritoneal fluid and blood women with endometriosis. CXCL12 mediates its action by interaction specific receptor, CXCR4, to be elevated human endometriosis lesions the rat model Activation CXCR4-CXCL12 axis increases cell proliferation, migration, invasion cancer cells. To obtain insights into CXCR4 expression profile endometrium, as well functionality endometriosis, we analyzed tissues on a tissue array studied...