A5038048953- Chronic Myeloid Leukemia Treatments
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Eosinophilic Disorders and Syndromes
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Acute Lymphoblastic Leukemia research
- Lymphoma Diagnosis and Treatment
- Epigenetics and DNA Methylation
- Head and Neck Cancer Studies
- Multiple Myeloma Research and Treatments
- Mast cells and histamine
- Cancer Diagnosis and Treatment
- Liver Disease and Transplantation
- Monoclonal and Polyclonal Antibodies Research
- Immune Cell Function and Interaction
- Protein Degradation and Inhibitors
- Economic and Financial Impacts of Cancer
- CAR-T cell therapy research
- Cancer-related gene regulation
- Cancer Genomics and Diagnostics
- Kruppel-like factors research
- Childhood Cancer Survivors' Quality of Life
- Lung Cancer Treatments and Mutations
- Colorectal Cancer Treatments and Studies
- Autoimmune and Inflammatory Disorders Research
Jena University Hospital
2016-2025
University of Maryland, Baltimore
2024
Johns Hopkins University
2024
Comprehensive Cancer Center Mainfranken
2024
Klinikum Magdeburg
2014-2023
University of Southampton
2008-2023
Friedrich Schiller University Jena
2021
Reha Rheinfelden
2020-2021
Center for Clinical Studies
2021
Seagen (United States)
2018
Anaplastic thyroid carcinoma is an aggressive malignancy that almost always fatal and lacks effective systemic treatment options for patients with
To determine whether proton MRS (1H MRS) can detect long-term metabolite abnormalities in abstinent methamphetamine users.Methamphetamine is toxic to dopaminergic and serotonergic neurons rodents; however, little data are available on the effects of human brain.1H was performed 26 abusers with a history dependence (median total cumulative lifetime exposure, 3,640 g; median recency last use, 4.25 months) 24 healthy subjects without drug abuse. Cerebral concentrations 1H were measured frontal...
<b><i>Objective:</i></b> To determine whether cerebral metabolite abnormalities normalize with highly active antiretroviral therapy (HAART). <b><i>Background:</i></b> Patients HIV–cognitive motor complex (HIV-CMC) show in the early stages of dementia. <b><i>Methods:</i></b> Sixteen patients HIV-CMC were evaluated before and after HAART, compared 15 HIV-negative healthy volunteers. Cerebral ratios concentrations frontal lobe basal ganglia measured using proton MRS (<sup>1</sup>H MRS)....
PURPOSE: To determine whether hydrogen-1 magnetic resonance (MR) spectroscopy of the brain allows detection subclinical hepatic encephalopathy (SCHE). MATERIALS AND METHODS: In a double-blind study, overt (HE) and SCHE (defined with clinical neuropsychiatric tests) were compared by means H-1 MR spectroscopic criteria--reduction in cerebral myo-inositol (< 2 standard deviations [SDs] from normal) choline SDs or without increased glutamine (> 1 SD normal)--in 20 patients cirrhosis. RESULTS:...
Abstract Purpose Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome emerging from deregulated immune response due to various triggers. In adults, systematic data are sparse, which why recommendations on diagnosis and management have been adopted pediatric guidelines. A nationwide clinical registry with associated consulting service as collaborative initiative of HLH-specialized pediatricians hematologists was initiated better characterize HLH in adults. Methods...