- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Hepatocellular Carcinoma Treatment and Prognosis
- Cardiac, Anesthesia and Surgical Outcomes
- Pancreatitis Pathology and Treatment
- Surgical Simulation and Training
- Liver Disease Diagnosis and Treatment
- Appendicitis Diagnosis and Management
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Surgical Treatments
- Anatomy and Medical Technology
- Cancer, Lipids, and Metabolism
- Lung Cancer Research Studies
- Cancer Immunotherapy and Biomarkers
- Colorectal Cancer Treatments and Studies
- Esophageal Cancer Research and Treatment
- Simulation-Based Education in Healthcare
- Organ Transplantation Techniques and Outcomes
- Gallbladder and Bile Duct Disorders
- Abdominal Trauma and Injuries
- Breast Implant and Reconstruction
- Liver Disease and Transplantation
- Advances in Oncology and Radiotherapy
- Intraperitoneal and Appendiceal Malignancies
- Gastrointestinal Tumor Research and Treatment
National and Kapodistrian University of Athens
2014-2025
University College London
2016-2025
University of Thessaly
2025
The Royal Free Hospital
2014-2025
University of West Attica
2025
University General Hospital Attikon
2023-2024
University of Hull
2023
Royal Free London NHS Foundation Trust
2015-2020
Aretaeio Hospital
2011-2016
Royal London Hospital
2016
The liver is one of the organs most commonly affected by metastasis. presence metastases has been reported to be responsible for an immunosuppressive microenvironment and diminished immunotherapy efficacy. Herein, we aimed investigate role IL-10 in metastasis determine how its modulation could affect efficacy vivo.
Investigation of expression profile well-established microRNAs in pancreatic adenocarcinoma, and its correlation with clinicopathological factors.Eighty-eight samples ductal adenocarcinoma 98 control were analyzed by real-time polymerase chain reaction for miR-21, miR-31, miR-122, miR-145, miR-146a, miR-155, miR-210, miR-222 expressions. The results normalized then statistically using nonparametric statistical tests.According to our results, miR-221, miR-222, overexpressed diseased tissues...
Abstract Background One-fifth of patients with a preoperative diagnosis ductal carcinoma in situ (DCIS) have invasive breast cancer (IBC) on definitive histology. Sentinel lymph node dissection (SLND) is performed almost half women having surgery for DCIS Sweden. The aim the present study was to try minimize unnecessary SLND by injecting superparamagnetic iron oxide (SPIO) nanoparticles at time primary surgery, enabling be later, if IBC found specimen. Methods Women high risk presence...
Sentinel lymph node (SLN) biopsy is the standard of care for breast cancer patients with non-palpable axillary nodes. We evaluated usefulness contrast-enhanced ultrasonography in preoperative detection malignant SLNs.50 (median age: 60 years) underwent a color power Doppler intravenous contrast (Sonovue®) preoperatively, and findings suggestive metastatic disease to SLN were documented. The final histopathological report radiological record compared. Finally, sensitivity, specificity...
Metastasis is a cancer-related systemic disease and responsible for the greatest mortality rate among cancer patients. Interestingly, interaction between immune system cells seems to play key role in metastasis formation target organ. However, this complex network only partially understood. We previously found that IL-22 produced by tissue resident iNKT17 promotes cell extravasation, early step of metastasis. Based on these data, we aimed here decipher last formation. levels were increased...
Purpose. Radical surgical resection with adjuvant chemotherapy or chemo-radiotherapy is the most effective treatment for pancreatic ductal adenocarcinoma (PDAC). However, relatively few studies investigate prognostic significance of biological markers in PDAC. This study aims to look into expressions vimentin, Ki67, and CD44 PDAC specimens their potential implications survival. Method. The was designed as retrospective, were evaluated by immunohistochemistry 53 cases. Overall survival...