A5078024710- Advancements in Transdermal Drug Delivery
- Advanced Drug Delivery Systems
- Synthesis and biological activity
- 3D Printing in Biomedical Research
- Dermatology and Skin Diseases
- Antifungal resistance and susceptibility
- Coenzyme Q10 studies and effects
- Additive Manufacturing and 3D Printing Technologies
- Bee Products Chemical Analysis
- Synthesis and Characterization of Heterocyclic Compounds
- Polydiacetylene-based materials and applications
- Multicomponent Synthesis of Heterocycles
- Innovative Microfluidic and Catalytic Techniques Innovation
- Vitamin C and Antioxidants Research
- Contact Dermatitis and Allergies
- Cytokine Signaling Pathways and Interactions
- Lipid Membrane Structure and Behavior
- Biochemical Acid Research Studies
- Spectroscopy Techniques in Biomedical and Chemical Research
- Fungal Plant Pathogen Control
Aristotle University of Thessaloniki
2018-2024
The Janus kinase (JAK) and epidermal growth factor receptor (EGFR) have been considered as potential targets for cancer therapy due to their role in regulating proliferation survival of cells. In the present study, aromatic alkyl-amino analogs thiazole-based chalcone were selected experimentally theoretically investigate inhibitory activity against JAK2 EGFR proteins well anti-cancer effects on human cell lines expressing (TF1 HEL) (A549 A431). vitro cytotoxicity screening results...
Thiazole derivates as well chalcones, are very important scaffold for medicinal chemistry. Literature survey revealed that they possess wide spectrum of biological activities among which anti-inflammatory and antimicrobial.The current studies describe the synthesis evaluation antimicrobial activity twenty eight novel thiazole-based chalcones.The designed compounds were synthesized using classical methods organic synthesis. The in vivo was performed by microdilution method.All have shown...
Microneedles (MN) are miniature devices capable of perforating painlessly stratum corneum and delivering active ingredients in the inner epidermal layers. Hollow microneedles (HMNs) highly detailed objects due to their internal microchannels thus, fabrication with Additive Manufacturing (AM) is a challenging task. Vat polymerization techniques provide sufficient accuracy for such microstructures. Differentiated from other approaches where stereolithography 2-photon were adopted, this paper...