- Neonatal and fetal brain pathology
- Cardiac Arrest and Resuscitation
- Congenital Heart Disease Studies
- Traumatic Brain Injury and Neurovascular Disturbances
- Atomic and Subatomic Physics Research
- Traumatic Brain Injury Research
- Craniofacial Disorders and Treatments
- Hormonal and reproductive studies
- Medical Imaging and Pathology Studies
- Congenital heart defects research
- Ultrasound in Clinical Applications
- Intestinal Malrotation and Obstruction Disorders
- Fetal and Pediatric Neurological Disorders
- Congenital gastrointestinal and neural anomalies
- Sarcoma Diagnosis and Treatment
- Head and Neck Surgical Oncology
- Soft tissue tumor case studies
- Tracheal and airway disorders
- Head and Neck Anomalies
- Child Abuse and Related Trauma
- Gynecological conditions and treatments
- Ultrasound Imaging and Elastography
- Infectious Encephalopathies and Encephalitis
- Ultrasound and Hyperthermia Applications
- Oropharyngeal Anatomy and Pathologies
Children's Hospital of Pittsburgh
2018-2024
University of Pittsburgh
2002-2024
Madurai Medical College
2024
University of Pittsburgh Medical Center
2023
Suven Life Sciences (India)
2022
Children's Hospital of Wisconsin
2013
Medical College of Wisconsin
2013
All India Institute of Medical Sciences
2006-2010
Apollo Hospitals
2008
University of Madras
1998
Abstract Background Rapid magnetic resonance imaging (MRI) protocols may be effective in the emergency department (ED) to evaluate nontraumatic neurologic complaints. We neuroimaging (rapid MRI [rMRI]), head computerized tomography [HCT], and full MRI) use following widespread implementation of rMRI a pediatric (ED). Methods conducted retrospective study tertiary care ED encounters with during two 9-month periods: one prior (control period) after generalized availability 4 (rMRI period). The...
Families and clinicians have limited validated tools available to assist in estimating long-term outcomes early after pediatric cardiac arrest. Blood-based brain-specific biomarkers may be helpful aid outcome assessment. To analyze the association of blood-based brain injury biomarker concentrations with 1 year The Personalizing Outcomes After Child Cardiac Arrest multicenter prospective cohort study was conducted intensive care units at 14 academic referral centers US between May 16, 2017,...
Importance Morbidity and mortality after pediatric cardiac arrest are chiefly due to hypoxic-ischemic brain injury. Brain features seen on magnetic resonance imaging (MRI) spectroscopy (MRS) may identify injury aid in outcome assessments. Objective To analyze the association of lesions T2-weighted MRI diffusion-weighted N-acetylaspartate (NAA) lactate concentrations MRS with 1-year outcomes arrest. Design, Setting, Participants This multicenter cohort study took place intensive care units at...
A 14 year old girl on multidrug treatment for borderline tuberculoid leprosy presented with a swelling in her left arm and soon thereafter developed ulnar claw hand. MRI showed well-defined ovoid lesion arising from the nerve, isointense to muscle T1W images hyperintense T2W STIR images. On post gadolinium sequence peripheral rim enhancement central necrosis suggestive of abscess. The nerve proximal distal was thickened mild contrast enhancement. aspiration yielded frank pus which positive...
A case of gonococcal urethritis with bilateral tysonitis and periurethral abscess is described. The diagnosis was made by microscopic detection typical gram-negative intracellular diplococci in cells the urethral discharge. patient treated oral ampicillin probenecid for ten days together oxytetracycline seven days; he responded favorably to antibiotics, surgical intervention unnecessary.
<h3>BACKGROUND AND PURPOSE:</h3> Pathogenic variants in the <i>ACTA2</i> gene cause a distinctive arterial phenotype that has recently been described to be associated with brain malformation. Our objective was further characterize gyral abnormalities patients pathogenic as per 2020 consensus recommendations for definition and classification of malformations cortical development. <h3>MATERIALS METHODS:</h3> We performed retrospective, multicentric review proved variants, searching presence A...
BACKGROUND. MRI is the reference standard for neonatal brain imaging, but it expensive, time-consuming, potentially limited by availability and accessibility, contraindicated in some patients. Transfontanelle head ultrasound an excellent alternative may be less sensitive specific than MRI. Contrast-enhanced (CEUS) has potential to improve capabilities of ultrasound. OBJECTIVE. The purpose this study prospectively evaluate feasibility, safety, diagnostic performance transfontanelle CEUS, with...
The impact of hyper- and hypothyroidism on prostatic glycosidases was investigated. Hyper-thyroidism induced by administering L-thyroxine (25 micrograms/100 g body weight/day) for 60 days total thyroidectomy. To test the direct influence thyroid hormones, lobes were incubated with different concentrations (10, 25 50 ng/mL) T3 beta-N-acetylglucosaminidase beta-N-acetylgalactosaminidase assayed. Serum levels oestradiol testosterone increased in hyperthyroid, decreased hypothyroid rats. TSH an...
A 42-month-old boy presented with frequent left partial motor seizures of 3 months duration. The symptoms began after an acute episode fever, encephalopathy, vomiting, and lasting 1 week. CSF was unremarkable negative for HSV PCR. Evaluation procoagulant states negative. …
Case Reports| February 09 2011 Aspiration Cytology of Mesenchymal Hamartoma the Chest Wall in an Infant: A Report Subject Area: Pathology and Cell Biology Sandeep R. Mathur; Mathur From Departments Pathology, Radiology Pediatric Surgery, All India Institute Medical Sciences, New Delhi, India. Search for other works by this author on: This Site PubMed Google Scholar Ruchika Gupta; Gupta Ashu Seith; Seith Agarwala; Agarwala Subramanian Subramanian; Datta Acta Cytologica (2010) 54 (1): 63–65....
A four-year-old male child presented with increased Typically the lesions are round or oval-shaped wellurine output and excessive thirst for eight months. On defined margins bevelled edge. Individual examination he had multiple scalp swellings mild may coalesce giving a geographic appearance to skull hepatosplenomegaly. Urine specific gravity was decreased suggestive of diabetes insipidus. Skull radiograph revealed well-defined lytic in calvarium [Figure 1]. MR sella, posterior pituitary...
Background: Brain magnetic resonance imaging (MRI) of infants with congenital heart disease (CHD) shows brain immaturity assessed via a cortical-based semi-quantitative score. Our primary aim was to develop an infant paralimbic-related subcortical-based dysmaturation score, termed dysplasia score (BDS), detect abnormalities in CHD compared healthy controls and secondarily predict clinical outcomes. We also validated our BDS preclinical mouse model hypoplastic left syndrome. Methods: A...
Motivation: Develop and validate point-of-care MRI-based evaluation method for scoring brain dysplasia/abnormality (BDS) in congenital heart disease (CHD) that incorporates morphological alterations subcortical structures. Goal(s): Further develop our BDS system, previously validated infants with CHD, the older pediatric young adult CHD population. Approach: Evaluate dysplasia from T1 T2 structural MRI of control participants compare differences. Correlate executive function outcomes genetic...