- Head and Neck Surgical Oncology
- Sinusitis and nasal conditions
- Ear Surgery and Otitis Media
- Ear and Head Tumors
- Nasal Surgery and Airway Studies
- Vestibular and auditory disorders
- Bone Tumor Diagnosis and Treatments
- Cerebral Venous Sinus Thrombosis
- Ophthalmology and Eye Disorders
- Glaucoma and retinal disorders
- Facial Nerve Paralysis Treatment and Research
- Cerebrospinal fluid and hydrocephalus
- Voice and Speech Disorders
- Infectious Diseases and Mycology
- Mitochondrial Function and Pathology
- Meningioma and schwannoma management
- Neurofibromatosis and Schwannoma Cases
- Obstructive Sleep Apnea Research
- Congenital heart defects research
- Airway Management and Intubation Techniques
- Asthma and respiratory diseases
- Cleft Lip and Palate Research
- Neurosurgical Procedures and Complications
- Phonetics and Phonology Research
- Herpesvirus Infections and Treatments
Toho University
2019-2025
Shonan Kamakura General Hospital
2022-2025
Toho University Omori Medical Center
2019-2025
St. Marianna University School of Medicine
2022-2024
Jikei University School of Medicine
2023
State of Illinois
2020
University Medical Center
2019
Abstract The MYO7A gene is known to be responsible for both syndromic hearing loss (Usher syndrome type1B:USH1B) and non-syndromic including autosomal dominant recessive inheritance (DFNA11, DFNB2). However, the prevalence detailed clinical features of -associated across a large population remain unclear. In this study, we conducted next-generation sequencing analysis cohort 10,042 Japanese patients. As result, 137 patients were identified with so that among was 1.36%. We 70 disease-causing...
Postoperative haemorrhage following palatine tonsillectomy occurs in 5-14% of cases. Since 2021, our department has used knot suturing with 3-0 Vicryl, and from 2023, continuous the V-Loc™ closure device to reduce suture time. While is reported postoperative bleeding pain, no studies have compared outcomes between different methods. This study retrospectively analysed bleeding, complications 125 patients undergoing tonsillectomy, or without sutures. Patients aged ≥15 years who underwent...
Abstract Objective This study investigated the position of adduction thread attachment, pulling direction and fixation in revision arytenoid surgery performed two patients with left vocal fold palsy whom satisfactory speech improvement had not been obtained by type 1 thyroplasty. Methods Revision was midline both cases. A thyroplasty procedure subsequently added one case because worsened quality following adduction. Results conclusion Although is conceptually well established, there still...
This study investigated the relationships between anatomical findings around eustachian tube (ET) and eosinophilic otitis media (EOM) accompanied by chronic rhinosinusitis (ECRS).This employed axial, coronal, sagittal oblique computed tomography.Patients who underwent endoscopic sinus surgery at Department of Otolaryngology, Toho University Medical Center Omori Hospital were diagnosed with ECRS (106 patients) based on Japanese Epidemiological Survey Refractory Eosinophilic Chronic...
Abstract Sinonasal inverted papilloma (IP) is at risk of recurrence and malignancy, early diagnosis using nasal endoscopy essential. We thus developed a diagnostic system artificial intelligence (AI) to identify sinus papilloma. Endoscopic surgery videos 53 patients undergoing endoscopic were edited train evaluate deep neural network models then was developed. The correct rate based on visual examination by otolaryngologists also evaluated the same compared with that AI patients. Main...
This study evaluated the therapeutic effect of hyperbaric oxygen therapy (HBOT) combined with steroid to treat sudden hearing loss and examined index associated excellent effect.We included 109 patients loss. Patients were divided into HBOT combination group (59 sides) treated noncombination (50 involving only. The recovery rate each was compared according severity Blood samples inflammatory markers, such as neutrophil-lymphocyte ratio (NLR) platelet-lymphocyte (PLR), calculated by severity....
Abstract Sinonasal inverted papilloma (IP) is at risk of recurrence and malignancy, early diagnosis using nasal endoscopy essential. We thus developed a diagnostic system artificial intelligence (AI) to identify sinus papilloma. Endoscopic surgery videos 53 patients undergoing endoscopic were edited train evaluate deep neural network models then was developed. The correct rate based on visual examination by otolaryngologists also evaluated the same compared with that AI patients. Main...
Established treatment strategies for nontuberculous mycobacterial (NTM) infections are currently lacking, and whether surgical should be applied in combination with antibiotic therapy remains debatable. Here, we report a case of bilateral otitis media caused by Mycobacterium abscessusa, highly antibiotic-resistant bacterium. Many reported cases NTM unilateral, which hearing the contralateral ear is preserved. In present case, to improve outcomes were considered, as both ears affected. A...
Although idiopathic temporal cerebrospinal fluid (CSF) leaks are a relatively rare condition, its incidence has been increasing in the United States recent years. Fistulas commonly occur middle cranial fossa (MCF), and MCF approach is recommended for multiple or large fistulas. Here, we present case of bilateral CSF The patient had small fistulas posterior fossae, which were successfully treated using transmastoid (TM) approach, proper postoperative management pressure resulted favorable...
Large vestibular aqueduct syndrome (LVAS) is a congenital malformation characterized by an abnormally large aqueduct, diagnosed primarily via CT scans. Patients with LVAS often experience progressive hearing loss and recurrent vertigo, treatment strategies mirroring those for Meniere's disease. Traditional surgical interventions such as endolymphatic sac decompression (ESD) are common; however, the efficacy of duct blockage (EDB) alternative still remains under investigation. We present case...
Background Forehead wrinkling ability has been considered to be the sign of central facial palsy (CFP).
We aimed to evaluate the morphology of external auditory canal (EAC) using a three-dimensional (3D) reconstruction computed tomography (CT) scans temporal bone corroborate and predict important anatomical structures involved in middle ear surgery based on EAC morphology.Temporal CT from 62 patients (120 ears) was used perform 3D (maximum intensity projection), which 32 (60 had chronic otitis media 30 normal bones. The EAC, tympanic sinus, vertical portion facial nerve, jugular bulb were...
Objectives This study investigated morphological variations of lamina papyracea, the structure that should be carefully considered when opening posterior ethmoid sinus during endoscopic surgery, to avoid injury. Study design employed axial, coronal, and sagittal computed tomography. Methods Using tomography images 228 face‐sides, various anatomical parameters were determined: distances anterior arteries from skull base, third lamella; changes in angles papyracea at sinuses; presence or...
Abstract Introduction Chronic rhinosinusitis (CRS) is commonly classified based on the presence or absence of nasal polyps (NPs). Eosinophil infiltration observed in NPs patients Western countries. In contrast, East Asian countries, including Japan, CRS with (CRSwNP) subdivided (eosinophilic [ECRS]) (non-eosinophilic [NECRS]) eosinophils NPs. However, detailed analyses other immune cells, such as lymphocytes, have not been performed. Therefore, clarification types cells that infiltrate...
Vertical nystagmus is an important sign of central nervous system disorder. Herein, we report a case upbeat nystagmus, in as the initial symptom clinically isolated syndrome. The patient was 45-year-old male who developed dizziness on November 7 and visited our hospital 12. We observed gaze all direction primary positions adduction failure right eye. hospitalized because MRI revealed high-intensity area posterior aspect pons medulla oblongata T2-weighted FLAIR imaging. started anticoagulant...
Abstract Purpose We aimed to evaluate the morphology of external auditory canal (EAC) using a three-dimensional (3D) reconstruction computed tomography (CT) scans temporal bone corroborate and predict important anatomical structures involved in middle ear surgery based on EAC morphology. Methods Temporal CT from 62 patients (120 ears) was used perform 3D (maximum intensity projection), which 32 (60 had chronic otitis media 30 normal bones. The EAC, tympanic sinus, vertical portion facial...
Facial nerve paralysis is unilateral in most cases, and cases of bilateral facial are rare. In particular, simultaneous very We encountered a patient with malignant lymphoma who developed during chemotherapy. A 72-year-old man diagnosed as having Hodgkin’s disease was hospitalized the second course AVD therapy suspected febrile neutropenia, 5 days before our first examination. He complained difficulty moving his lips, referred to department following day. Examination at revealed scarce...
Abstract Purpose: We aimed to evaluate the morphology of external auditory canal (EAC) using a three-dimensional (3D) reconstruction computed tomography (CT) scans temporal bone corroborate and predict important anatomical structures involved in middle ear surgery based on EAC morphology. Methods: Temporal CT from 62 patients (120 ears) was used perform 3D (maximum intensity projection), which 32 (60 had chronic otitis media 30 normal bones. The EAC, tympanic sinus, vertical portion facial...