A5077410267- Prenatal Screening and Diagnostics
- Pregnancy and preeclampsia studies
- Assisted Reproductive Technology and Twin Pregnancy
- Birth, Development, and Health
- Ectopic Pregnancy Diagnosis and Management
- Cardiovascular Issues in Pregnancy
- Maternal and fetal healthcare
- Gestational Diabetes Research and Management
- Congenital Anomalies and Fetal Surgery
- Congenital Diaphragmatic Hernia Studies
- Preterm Birth and Chorioamnionitis
- Endometriosis Research and Treatment
- Genetic Syndromes and Imprinting
- Endometrial and Cervical Cancer Treatments
- Neonatal and fetal brain pathology
- Ethics and Legal Issues in Pediatric Healthcare
- Social and Educational Sciences
- Cancer Risks and Factors
- Diabetic Foot Ulcer Assessment and Management
- Cultural Differences and Values
- Gynecological conditions and treatments
- Autopsy Techniques and Outcomes
- Genomics and Rare Diseases
- Renal and related cancers
- Urological Disorders and Treatments
Odense University Hospital
2015-2025
University of Southern Denmark
2014-2025
Lillebaelt Hospital
2022
Copenhagen University Hospital
2012
University of Copenhagen
2012
Rigshospitalet
2012
Medical University of Graz
2012
Vienna General Hospital
2012
Medical University of Vienna
2012
University Hospital Innsbruck
2012
We report an epidemic of parvovirus B19 infections in Denmark during the first quarter 2024, with a peak incidence 3.5 times higher than most recent 2017. In total, 20.1% (130/648) laboratory-confirmed cases were pregnant. Severe adverse outcomes observed among 12.3% (16/130) pregnant people and included foetal anaemia, hydrops miscarriage. Parvovirus infection is not systematically monitored, but national laboratory-based surveillance system currently being established Denmark.
To investigate the predictive performance of Fetal Medicine Foundation (FMF) first-trimester screening algorithm for pre-eclampsia in a Danish population and compare with that current strategy, which is based on maternal risk factors.
To describe the establishment and organization of Danish Fetal Medicine Database to report national results first-trimester combined screening for trisomy 21 in 5-year period 2008-2012.National register study using prospectively collected data from Database.Pregnant women Denmark undergoing 21.Data on maternal characteristics, biochemical ultrasonic markers are continuously sent electronically local fetal medicine databases (Astraia Gmbh software) a central database. Data linked outcome...
ABSTRACT Objective To describe the implementation of whole genome sequencing (WGS) in prenatal diagnostics and outline national guideline system facilitating this. Methods Clinical guidelines for WGS were developed implemented by Danish Fetal Medicine Society. Results Guidelines expert consensus following a review 75 studies. Diagnostic yield served as key factor prioritizing various phenotypes, improving diagnostic accuracy informing clinical decisions. Phenotypes include nuchal...
Triplet pregnancies are high risk for both the mother and infants. The risks infants include premature birth, low birthweight, neonatal complications. Therefore, management of triplet involves close monitoring may interventions, such as fetal reduction, to prolong pregnancy improve outcomes. However, evidence benefits associated with reduction is inconsistent.
In Brief OBJECTIVE: To estimate the association between cytokine levels in twin pregnancies and risk of spontaneous preterm delivery, including effect progesterone treatment. METHODS: This secondary analysis a randomized placebo-controlled trial investigating treatment on delivery included 523 women with available dried blood spot samples collected before (n=258) or placebo (n=265) after 4–8 weeks Samples were analyzed for cytokines using sandwich immunoassay. Cytokine at 34–37 gestation 34...
Background The objective was to evaluate predictive performance and optimal decision threshold of the Kryptor soluble fms-like tyrosine kinase-1 (sFlt-1)/placental growth factor (PlGF) ratio when implemented for routine management women presenting with symptoms preeclampsia. Methods Results Observational retrospective study a cohort 501 suspected preeclampsia after 20 weeks gestation. Women referred maternity ward observation had an sFlt-1/PlGF test included in diagnostic workup. Maternal...
To investigate the performance of second-trimester ultrasound scan regarding ultrasound-detectable congenital malformations in a Danish region. The study sample was population-based, with 6 months postnatal follow-up. Hospital records and autopsy reports were reviewed each case to validate prenatal diagnosis.This population-based cohort included all fetuses (n = 19.367) alive at four hospitals final diagnosis based on hospital during 6-month In termination or stillbirth, result from report...
An impact of maternal obesity on ultrasound dating pregnancy at 11-14 gestational weeks is possible and was investigated.A prospective cohort study based the Danish national population during a 4-year period in which we entered all mothers with singleton pregnancies who had known last menstrual (LMP), recorded booking body mass index (BMI), late first trimester scan using crown-rump-length measurement (gestational age 11+0 -13+6 weeks). Almost scans were performed transabdominally....
The detection of an abnormality during prenatal screening implies that the parents are informed about possible treatment and management pregnancy, birth, postnatal course. This information should enable to make decisions regarding especially in cases where termination pregnancy may be option. objectives this study were investigate how often doctors when fetus had anomaly which demographic factors related parental decision-making.This was a retrospective cohort with prospectively collected...
ABSTRACT Objective To assess the validity of Fetal Medicine Foundation (FMF) chorionicity‐specific models for fetal growth in twin pregnancy. Methods This was an external validation study FMF using a nationwide Danish cohort pregnancies. The included all dichorionic (DC) and monochorionic diamniotic (MCDA) pregnancies with estimated delivery date between 2008 2018, which satisfied following inclusion criteria: two live fetuses at first‐trimester ultrasound scan (11–14 weeks' gestation);...
Salpingitis isthmica nodosa (SIN) is a condition of nodular thickening the proximal Fallopian tube. The purpose this study was to investigate occurrence, distribution and frequency SIN in Danish women salpingectomized because tubal pregnancy or salpingitis correlate with infertility, pregnancies, outcome births, pelvic inflammatory disease salpingitis. Sections from isthmus were present specimens 223 tubes 193 patients analysed by same pathologist. Originally, found 12 but on re examination,...
ABSTRACT Objectives To describe the distributional properties and assess performance of placental growth factor (PlGF) measured in blood samples collected before 11 weeks' gestation prediction pre‐eclampsia (PE). Methods The study population consisted pregnant women included Pre‐eclampsia Screening Denmark (PRESIDE) with a PlGF measurement from routine combined first‐trimester screening (cFTS) sample at 8–14 gestation. PRESIDE was prospective multicenter investigating predictive Fetal...
Abstract Objectives To estimate the prevalence of kidney anomalies at second trimester ultrasound screening, and furthermore, to investigate pregnancy outcomes pattern additional malformations. Methods We previously identified all women attending second‐trimester scans in Denmark between 1 January 2007 31 December 2012. Using Astraia databases Danish National Patient Registry, we fetuses with diagnosed prenatally these women. In addition anomalies, estimated live birth ratio non‐urinary...
The study objective was to determine the parental origin of triploidy in relation findings from early risk assessment a combined screening program between 2004 and end 2006. Triploidy diagnosed six chorion villus samples two missed abortions. After informed consent, quantitative fluorescence polymerase chain reaction analysis performed on five cases where we received blood both parents tissue fetuses. In four paternal one maternal, accordance with previous type I II triploidies. Finding is...
Late-onset preeclampsia occurring after 34 weeks of gestation is the most common form preeclampsia, but little known about either etiology or prevention. Current detection methods for in early pregnancy have not shown promising results detecting late-onset preeclampsia. The aim this study was to assess whether apolipoproteins combination with maternal medical history and biophysical factors can be used as an method This nested case-cohort based at Odense University Hospital, Denmark. Women...
The aim of the study was to estimate proportion women giving birth in two hospitals Region Southern Denmark who did not attend malformation scan and elucidate reasons for participating.In this register-based descriptive study, we used patient administration systems identify had given at Danish between March 2013 January 2015. We then linked information with hospital database fetal medicine (Astraia) week 18-20. reviewed medical records these validate data reason non-participation.Of 7690...
This study aims to evaluate matrix metalloproteinase-7 as a first trimester biomarker for late-onset preeclampsia, both alone and in combination with mean arterial pressure, uterine artery pulsatility index, maternal characteristics.We conducted nested case-control from prospective cohort consisting of 416 pregnant women who attended routine scan. Baseline variables were obtained at inclusion analysed subsequently formation case control groups. The was designed detect difference > 15%...
<title>Abstract</title> As a cultural species, humans show marked global diversity in preferences, beliefs, and behaviors (cultural traits). Of the many types of traits, which ones generate most across countries? We address this question by analyzing data for 640,110 individuals from 117 countries, 2,333 sub-national districts worldwide, 13 birth cohorts surveyed World Values Survey (WVS) European Study (EVS). measure using standard Cultural Fixation Index (CFst). Across multiple sets...
To evaluate the influence of chorionicity on outcome in twin pregnancies, using a Danish national database including women having first trimester ultrasound and risk assessment. A cohort 3,372 dichorionic (DC) pregnancies 638 monochorionic (MC) (608 diamniotic, MCDA, 30 monoamniotic, MCMA) from period July 2008–July 2011 was collected fetal medicine database. The includes more than 97% assessment Denmark. Primary outcomes were loss rate before week 22, intrauterine death 22 to birth,...
To investigate the national prevalence and prenatal detection rate (DR) of major congenital heart disease (mCHD) in twin pregnancies without twin-to-twin transfusion syndrome (TTTS)-associated CHD a Danish population following standardized screening program.