A5100336437- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Congenital Diaphragmatic Hernia Studies
- Ferroptosis and cancer prognosis
- Lung Cancer Treatments and Mutations
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Lung Cancer Diagnosis and Treatment
- RNA modifications and cancer
- Gastric Cancer Management and Outcomes
- Brain Metastases and Treatment
- Airway Management and Intubation Techniques
- Inhalation and Respiratory Drug Delivery
- Birth, Development, and Health
- Pancreatic and Hepatic Oncology Research
- COVID-19 Clinical Research Studies
- Neonatal Health and Biochemistry
- Abdominal Surgery and Complications
- Medical Imaging and Pathology Studies
- Cancer Immunotherapy and Biomarkers
- Cancer, Lipids, and Metabolism
- Cardiovascular and Diving-Related Complications
- Respiratory viral infections research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Cardiac Arrest and Resuscitation
Chengdu Medical College
2023-2025
Children's Hospital of Chongqing Medical University
2019-2024
Chongqing Medical University
2018-2024
China International Science and Technology Cooperation
2019-2024
Air Force Medical University
2023
Xijing Hospital
2023
Zhejiang Provincial People's Hospital
2018-2023
Northwest A&F University
2023
Qilu Hospital of Shandong University
2023
Chengdu Second People's Hospital
2023
Abstract Head neck squamous cell carcinoma (HNSCC) is one of the most common malignant tumors which ranks sixth incidence in world. Although treatments for HNSCC have improved significantly recent years, its recurrence rate and mortality remain high. Myosin genes been studied a variety tumors, however role has not elucidated. GSE58911 GSE30784 gene expression profile analysis were performed to detect dys-regulated myosin HNSCC. The Cancer Genome Atlas (TCGA) database was used verify study...
A novel coronavirus (COVID-19) outbreak has occurred in China, and national medical workers have been thrown into this silent battle. Paediatric an important part of battle under enormous pressure. This paper evaluates the depression, anxiety, stress paediatric staff during epidemic examines related impact factors.We conducted study using online questionnaires via social networking software week Feb. 17 to 23, 2020. The 21-item Depression Anxiety Stress Scale (DASS), which is a revised,...
Abstract Background Ferroptosis have been implicated in tumorigenesis, tumor progression, and chemo- immuno-therapy cirrhotic hepatocellular carcinoma (HCC), indicating its association with matrix stiffness clinical benefit of targeting drugs or immune checkpoint inhibitor. Here, we postulated that increased reduces ferroptosis impairs immunity by regulating the expression ferroptosis- immune-related genes HCC, which might be a robust predictor therapeutic efficacy. Methods Using publicly...
The present study was designed and conducted to compare the efficacy between nasal continuous positive airway pressure (NCPAP), intermittent positive-pressure ventilation (NIPPV), noninvasive high-frequency oscillatory (NHFOV) as primary in preterm infants with respiratory distress syndrome (RDS).This multicenter retrospective cohort performed using data from four tertiary neonatal intensive care units (NICUs) China 2016 2018. 512 RDS who received early non-invasive (NIV) were analyzed....
Moderate-to-severe post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis contributes to most of the poor outcomes patients with post-ERCP (PEP). However, it remains unclear which part patient is more vulnerable moderate-to-severe PEP (MS PEP). In this study, we aimed identify risk factors independently associated MS PEP.Consecutive native papilla who had undergone ERCP were included in study. The patient-related and procedure-related variables retrieved from a prospectively...
<title>Abstract</title> <bold>Background</bold> Autophagy and ferroptosis are important processes that control cell survival death. They help keep the body's balance respond to stress. Since was first described in 2012, researchers have been interested how it works with autophagy. This interaction is especially diseases like cancer, brain disorders, heart problems. In these diseases, autophagy can work together or against each other, leading complex biological effects. Because many studies...
Abstract Noninvasive ventilation has been proven to be effective strategies for reducing the need endotracheal in preterm infant with respiratory distress syndrome (RDS), however best option needs further determined. A single center, paired design, randomized, controlled trial was conducted between Jan 2011 and July 2014. Preterm twins RDS were included. One of a pair randomized NIPPV, while another NCPAP. Surfactant administrated as rescue treatment. The primary outcome ventilation....
Abstract Background Erlotinib combined with whole-brain radiotherapy (WBRT) demonstrated a favorable objective response rate in phase II single-arm trial of non–small cell lung cancer (NSCLC) patients brain metastases. We assessed whether concurrent erlotinib WBRT is safe and benefits III, randomized trial. Methods NSCLC two or more metastases were enrolled randomly assigned (1:1) to (n = 115) arms 109). The primary endpoint was intracranial progression-free survival (iPFS) cognitive...
The coronavirus disease 2019 (COVID-19) outbreak became the worst epidemic in decades. Since its inception, COVID-19 has had a dramatic impact on chronic obstructive pulmonary (COPD) patients. This study explores explore current status, hot spots, and research frontiers of COPD based bibliometric approach. Web Science Core Collection was used to search literature related COVID-19, VOSviewer CiteSpace software were applied analyze distribution characteristics, hotspots, fields map scientific...
Abstract Increasing evidence has demonstrated that lung fluid absorption disorders might be an important cause of neonatal respiratory distress syndrome (RDS) by influencing gas exchange or surfactant function. The SCNN1A gene, which encodes the α-ENaC, predispose infants to RDS. To explore whether single-nucleotide polymorphisms (SNPs) are associated with RDS, we conducted a case-control study investigate RDS-associated loci in Han Chinese infants. Seven target SNPs were selected from gene...
Abstract Background Zinc oxide nanoparticles (ZONs) are a type of nanomaterial that has presented anti-cancer properties in breast cancer (BC). However, the function ABCC9 BC and its correlation with ZONs still elusive. Methods Here, we identified crucial role modulating ferroptosis doxorubicin (Dox) resistance targeted to ABCC9. Results The silencing significantly repressed viability cells. knockdown decreased numbers Edu-positive Conversely, cell apoptosis was increased by inhibition...
Abstract Purpose Low serum creatinine/cystatin C ratio (CCR) is associated with unfavorable characteristics in patients chronic obstructive pulmonary disease (COPD); however, the relationship between CCR and in-hospital mortality of acute exacerbation COPD (AECOPD) unexplored. Our objective was to assess value for predicting hospitalized AECOPD. Methods Patients AECOPD ( n = 597) were retrospectively enrolled. Patient’s clinical laboratory tests, including cystatin creatinine, reviewed. The...