Wen Li

ORCID: 0000-0003-2360-9831
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About
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Research Areas
  • Birth, Development, and Health
  • Prenatal Screening and Diagnostics
  • Global Health Workforce Issues
  • Pregnancy and preeclampsia studies
  • Higher Education and Teaching Methods
  • Fetal and Pediatric Neurological Disorders
  • Genomic variations and chromosomal abnormalities
  • Education and Work Dynamics
  • Cardiovascular Issues in Pregnancy
  • Folate and B Vitamins Research
  • COVID-19 and Mental Health
  • Global Health and Surgery
  • Pharmacological Effects and Toxicity Studies
  • Family Support in Illness
  • Congenital Heart Disease Studies
  • Gestational Diabetes Research and Management
  • Metabolism and Genetic Disorders
  • Diversity and Career in Medicine
  • Migration, Health and Trauma
  • Innovations in Medical Education
  • Parvovirus B19 Infection Studies
  • Maternal Mental Health During Pregnancy and Postpartum
  • Infant Nutrition and Health
  • Childhood Cancer Survivors' Quality of Life
  • Obesity, Physical Activity, Diet

The University of Queensland
2024-2025

Tianjin Medical University
2018-2025

Reproductive & Genetic Hospital CITIC-Xiangya
2016-2025

Zhejiang Chinese Medical University
2024-2025

National Engineering Research Center of Human Stem Cells
2016-2025

Central South University
2002-2025

First People's Hospital of Yuhang District
2024

Xuzhou Medical College
2018-2024

Second Affiliated Hospital of Zhejiang University
2024

Chongqing Medical University
2023-2024

Abstract Background The COVID-19 pandemic posed a huge challenge to the education systems worldwide, forcing many countries provisionally close educational institutions and deliver courses fully online. aim of this study was explore quality online in China for international medical nursing students from low- middle-income (LMICs) as well factors that influenced their satisfaction with during pandemic. Methods Questionnaires were developed administered 316 120 teachers at university China....

10.1186/s12960-021-00609-9 article EN cc-by Human Resources for Health 2021-05-12

Abstract Objective The objective of the study is to report performance noninvasive prenatal testing (NIPT) in twin pregnancies after treatment assisted reproductive technology (ART). Method In two years period, 565 pregnant women with ART were prospectively tested by NIPT for screening trisomy 21 (T21), 18 (T18), and 13 (T13) sequencing cell‐free DNA maternal plasma. Positive results confirmed karyotyping, while negative interviewed delivery. Pregnant decision based on confirmation was...

10.1002/pd.4837 article EN Prenatal Diagnosis 2016-05-06

Abstract Background In recent years, the number of students from Asian and African countries to study medicine in China has been on rise. This investigated migration intentions China-educated international medical (IMSs) after graduation factors that influence intentions. Methods The cross-sectional, questionnaire-based involved IMSs 2nd 6th year degree course at Xuzhou Medical University, China, conducted April July 2018. self-administrated questionnaire asked questions students’...

10.1186/s12960-019-0431-z article EN cc-by Human Resources for Health 2019-11-21

Exploring the correlations between ecosystem service value (ESV) and landscape ecological risk driving factors of their spatial variations is crucial for maintaining regional security promoting sustainable human well-being. We carried out a grid resampling size 5 km×5 km assessment units Jilin Pro-vince based on remote sensing monitoring data land use in 2000, 2005, 2010, 2015, 2020. quantitatively evaluated ESV, analyzed spatial-temporal variations. Employing bivariate autocorrelation...

10.13287/j.1001-9332.202403.022 article EN PubMed 2024-03-18

Periconceptional maternal folate levels may alter DNA methylation patterns and health outcomes in offspring. We hypothesized that folic acid supplementation alters fetal neural development through the brain. Twenty-eight rats were randomly assigned to four groups: three groups of female fed folate-normal, folate-deficient or folate-supplemented diets from seven days before mating delivery. In another group, diet short-period group was a folate-normal diet, except for 10 (begin mating) when...

10.3390/nu10030292 article EN Nutrients 2018-03-01

Abstract Background Traditional fixed thresholds for oral glucose tolerance test (OGTT) results may inadequately prevent adverse pregnancy outcomes in twin pregnancies. This study explores latent OGTT patterns and their association with outcomes. Methods retrospectively analyzed 2644 pregnancies using mixture models to identify level (high, HG; medium, MG; low, LG) relationship maternal/neonatal characteristics, gestational age at delivery, Results Three distinct patterns, HG, MG, LG were...

10.1111/1753-0407.70016 article EN cc-by Journal of Diabetes 2024-10-01

Abstract Nonalcoholic fatty liver disease (NAFLD) is one of the most common chronic diseases and associated with Alzheimer's (AD). Both docosahexaenoic acid (DHA) medium chain triglycerides (MCTs) play essential roles in lipid metabolism inhibition amyloid‐β (Aβ) accumulation. We aimed to explore possible association between cerebral Aβ deposition development NAFLD investigate effect DHA combined MCTs on delaying progression To this end, 40 three‐month‐old APP/PS1 male mice were randomly...

10.1002/lipd.12436 article EN Lipids 2025-02-25

Background: Chinese-Australian adolescents face unique academic and cultural challenges that may impact their lifestyle psychological well-being. Physical activity, screen time, sleep are known to influence However, research on the adherence 24-Hour Movement Guidelines among remains limited awaits further investigation. Objective: This study hypothesized a significant positive association between for physical sleep, well-being of adolescents. Methods: A self-reported questionnaire was...

10.3390/children12030329 article EN cc-by Children 2025-03-05

Elevated intra-abdominal pressure can engender a spectrum of adverse physiological repercussions in patients, but further research is needed to ascertain whether elevated exerts significant effects on renal function. The study used MIMIC-IV database identify critical patients with IAP monitoring. Patients were categorized into Low-IAP and High-IAP groups based the results restricted cubic splines curve, HR = 1 set at 16 mmHg. primary outcome was occurrence AKI within 72 h ICU admission,...

10.1038/s41598-024-84831-0 article EN cc-by-nc-nd Scientific Reports 2025-03-10

Abstract Background As the number of Asian and African students studying medicine in China increases, it is imperative to evaluate educational experiences these international medical (IMSs). This study was intended investigate opinions China-educated IMSs towards curriculum impact Chinese language capability on their clinical studies. Methods A self-administered questionnaire circulated final-year during graduation time from May 2019 July 4 universities China. The asked assess quality...

10.1186/s12909-020-02340-w article EN cc-by BMC Medical Education 2020-11-07

Abstract Background The outbreak of COVID-19 has led to increased workload and infection risks among medical staff. This situation may influence current health-related students’ decision on the choices their future careers. Hence, this study investigated impact career intentions. Methods is a cross-sectional observational that included students from three universities between October 2020 January 2021. questionnaire was divided into two main sections: Section 1, which comprised basic...

10.1186/s12909-021-02922-2 article EN cc-by BMC Medical Education 2021-09-09

This study explored the specialty preferences of China-educated international medical students (IMSs), who are mainly from low- and middle-income countries (LMICs) constitute a potential workforce both for their home foreign countries, influence migration intentions on preferences.A cross-sectional, questionnaire-based survey was conducted at 5 universities in China. The questionnaire link distributed electronically among IMSs via emails. enquired IMSs' demographic information, preferences....

10.1186/s12909-023-04123-5 article EN cc-by BMC Medical Education 2023-03-15

The effect of maternal folate status on the fetal central nervous system (CNS) is well recognized, while evidence emerging that such an association also exists between fathers and offspring. biological functions telomeres telomerase are related to neural cell proliferation apoptosis. study aimed investigate parental deficiency apoptosis stem cells (NSCs) in neonatal offspring role this effect. In study, rats were divided into four groups: folate-deficient paternal diet (D-D) group;...

10.3390/nu15132843 article EN Nutrients 2023-06-22

Abstract China hosts around 68,000 international medical students (IMSs) primarily from lower income countries in Africa and Asia, who have the potential to contribute services. Understanding how these IMSs make career decisions can help better address issue of global workforce shortage. However, such research is limited. Our study aims explore decision-making process China-educated IMSs, challenges they experienced strategies employed. In this exploratory qualitative study, we conducted...

10.1007/s10459-024-10329-z article EN cc-by Advances in Health Sciences Education 2024-04-09

To investigate trajectories of early childhood sleep in the first three years and association with maternal depressive symptoms. Data was from 243 Chinese mother-child dyads. Children's duration night-waking were assessed using Brief Infant Sleep Questionnaire (BISQ) at 42 days, 3, 6, 9, 12, 18, 24, 36 months postpartum. The Center for Epidemiological Survey-Depression Scale (CES-D), Edinburgh Postnatal Depression (EPDS), Profile Mood States (POMS) used to assess symptoms late pregnancy,...

10.1093/sleep/zsac037 article EN SLEEP 2022-02-15

Abstract The relationship between childhood socioeconomic status (SES) and type 2 diabetes (T2D) remains inconclusive, the pathways mechanisms driving this have yet to be clarified. This study aimed examine linking SES T2D prevalence in mid-late adulthood a low- middle-income country. incidence of diagnosed Chinese was assessed using self-reports from Health Retirement Longitudinal Study (CHARLS). Childhood by education, occupation, survivorship parents financial situation family, whereas...

10.1038/s41598-021-91768-1 article EN cc-by Scientific Reports 2021-06-22

<b><i>Background/Aims: </i></b>The objective of this study was to examine the responses p53 promoter methylation involved in kidney structure and function early weaning intrauterine growth retarded (IUGR) rats dietary folic acid supplementation. <b><i>Method: </i></b>Sprague-Dawley were fed isocaloric diets containing either 21% protein diet (normal feed) or 10% throughout pregnancy normal feed during lactation. After weaning, Offspring then...

10.1159/000368516 article EN cc-by-nc Kidney & Blood Pressure Research 2015-01-01

Abstract Objective Acute bilirubin encephalopathy (ABE) remains one of the important causes neonatal mortality and child disability, early identification, intervention which could improve outcomes. The purpose this study was to evaluate predictors adverse outcomes in infants with ABE. Methods Newborns gestational age ≥ 35 weeks diagnosed ABE were included study. Bilirubin‐induced neurological dysfunction (BIND) score, total serum (TSB) peak value, albumin levels determined. Adverse defined...

10.1002/acn3.51077 article EN cc-by Annals of Clinical and Translational Neurology 2020-06-04

Early life stage folate status may influence neurodevelopment in offspring. The developmental origin of health and disease highlights the importance period first 1000 days (from conception to 2 years) life. This study aimed evaluate effect early folic acid deficiency on de novo telomere synthesis, neurobehavioral development, cognitive function offspring rats. rats were divided into three diet treatment groups: folate-deficient, folate-normal, folate-supplemented. They fed corresponding from...

10.3390/ijms23136948 article EN International Journal of Molecular Sciences 2022-06-22

Prenatal alcohol exposure-induced fetal syndrome (FAS) can lead to serious maldevelopment in many organ systems, including the eyes. In present study, effects of exposure on early development human retina and therapeutic resveratrol alcohol-induced neural retinal damage were observed for first time an vitro organoid model. We report that number proliferating apoptotic cells decreased increased, respectively, following ethanol treatment. addition, PAX6+ migrating TUJ1+ after exposure....

10.1002/2211-5463.13601 article EN cc-by FEBS Open Bio 2023-03-27
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