A5037855238- Oral microbiology and periodontitis research
- Dental materials and restorations
- Endodontics and Root Canal Treatments
- Dental Health and Care Utilization
- Oral and gingival health research
- Dental Research and COVID-19
- Dental Implant Techniques and Outcomes
- Antifungal resistance and susceptibility
- Streptococcal Infections and Treatments
- Photodynamic Therapy Research Studies
- Essential Oils and Antimicrobial Activity
- Antimicrobial Peptides and Activities
- Dental Radiography and Imaging
- Oral Health Pathology and Treatment
- Infective Endocarditis Diagnosis and Management
- Salivary Gland Disorders and Functions
- HIV/AIDS oral health manifestations
- Dental Erosion and Treatment
- Nanoplatforms for cancer theranostics
- Periodontal Regeneration and Treatments
- Oral health in cancer treatment
- Immune Response and Inflammation
- Probiotics and Fermented Foods
- Bone Tissue Engineering Materials
- Bacterial biofilms and quorum sensing
Universidade Estadual Paulista (Unesp)
2015-2024
Centro Universitário de Araraquara
2013-2024
Universidade de São Paulo
2008-2018
Universidade Paulista
2005-2015
Fundação Faculdade de Odontologia
2012
Universidade Estadual de Ponta Grossa
2008
Institute of Physiology and Basic Medicine
2005
Universidade Estadual de Campinas (UNICAMP)
1997
BackgroundAlthough previous studies have shown the presence of Porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, occurrence this pathogen diseased periodontal sites without lesions has been poorly investigated.ObjectiveThe aims study were to quantify P. patients evaluate potential correlation gingivalis and Tannerella forsythia, ability treatment reduce these pathogens.DesignPatients generalized selected by recording clinical attachment level (CAL),...
Given the spread of antibiotic resistance in bacterial pathogens, antimicrobial peptides that can also modulate immune response may be a novel approach for effectively controlling periodontal infections. In present study, we used three-dimensional (3D) co-culture model gingival epithelial cells and fibroblasts stimulated with Aggregatibacter actinomycetemcomitans lipopolysaccharide (LPS) to investigate anti-inflammatory properties human beta-defensin-3 (hBD-3) cathelicidin (LL-37) determine...
Triclosan is a general membrane-active agent with broad-spectrum antimicrobial activity that commonly used in oral care products. In this study, we investigated the effect of sub-minimum inhibitory concentrations (MICs) triclosan on capacity cariogenic bacterium Streptococcus mutans to form biofilm and adhere epithelial cells. As quantified by crystal violet staining, formation two reference strains S. was dose-dependently promoted, range 2.2- 6.2-fold, 1/2 1/4 MIC triclosan. Observations...
Background: The purpose of this study was to evaluate the effect a selective cyclooxygenase‐2 inhibitor on progression alveolar bone loss in an experimental periodontitis model rats. Methods: One hundred eighty (180) Wistar rats were separated into 3 groups. Cotton ligatures placed at gingival margin level lower right first molars. randomly assigned one following groups that received: daily oral dose 10 mg/kg body weight celecoxib (Cel); 20 (Ce2); or ml/kg saline solution (C). Serum levels...
The effectiveness of microwave disinfection maxillary complete dentures on the treatment Candida-related denture stomatitis was evaluated. Patients (n = 60) were randomly assigned to one four groups 15 subjects each;patients performed routine care; Mw group: patients had their upper microwaved (650 W per 6 min) three times week for 30 days; group MwMz: received in conjunction with topical application miconazole day Mz: antifungal therapy MwMz. Cytological smears and mycological cultures...
Abstract Purpose: This study evaluated the effectiveness of different exposure times microwave irradiation on disinfection a hard chairside reline resin. Materials and Methods: Sterile specimens were individually inoculated with one tested microorganisms ( Pseudomonas aeruginosa , Staphylococcus aureus Candida albicans Bacillus subtilis ) incubated for 24 hours at 37°C. For each microorganism, 10 not microwaved (control), 50 microwaved. Control immersed in sterile saline, replicate aliquots...
This study evaluated the clinical effectiveness of two exposure times microwave irradiation on disinfection complete dentures.Biofilm samples were collected from dentures 30 patients, who randomly divided into experimental groups 15 subjects each: Group 1-patients had their maxillary denture microwaved for 3 min (650W); 2-patients 2 (650W). Denture biofilm taken with swabs, before (left side surfaces) and after (right irradiation. All microbial material was plated selective media Candida...
The ability of Candida albicans to form biofilms on denture surfaces is a significant cofactor in the pathogenesis stomatitis. In this study, we applied differential staining approach and scanning electron microscopy (SEM) analyse effect sodium hypochlorite chlorhexidine gluconate viability, removal morphology C. forming acrylic using an vitro model. Immediately after treatment, distinguish live from dead cells remaining biofilms, specimens were stained differentially analysed by confocal...
Over the years, several studies have brought evidence suggesting that tea polyphenols, mostly from green tea, may oral health benefits. Since few data are available concerning beneficial properties of black and its theaflavin derivatives against periodontal disease, objective this study was to investigate their antibacterial activity as well ability modulate interleukin-8 human β-defensin (hBD) secretion in epithelial cells. Among periodontopathogenic bacteria tested, Porphyromonas...
This study evaluated the antibacterial activity of terpinen-4-ol against Streptococcus mutans and Lactobacillus acidophilus its influence on gbpA (S. mutans) slpA (L. acidophilus) gene expression. As measured by XTT assay, concentrations that effectively inhibited biofilm were 0.24% 0.95% for S. L. acidophilus, respectively. Confocal microscopy revealed presence a attached to enamel dentin block surfaces with significant effects these microorganisms. The expression genes involved in...
Anticaries agents must interfere with the adhesion of Streptococcus mutans and its proliferation in dental biofilm, without causing host toxicity bacterial resistance. Natural substances, including cationic antimicrobial peptides (CAMPs) their fragments, such as β-defensin-3 peptide fragment (D1-23), have been widely studied. However, chemical physical stability CAMPs may be compromised by external factors, temperature pH, reducing period activity.To overcome aforementioned disadvantage,...
In general, the consumption of flavonoid-rich foods may influence control/dysregulation magnitude and duration inflammation oxidative stress, which are known to contribute multiple pathologies.
This crossover study compared the efficacy of an ultrasonic toothbrush for reduction plaque, gingival inflammation, and levels Streptococcus mutans, in relation to electric a manual toothbrush.Twenty-one patients with orthodontic appliances were divided into three groups. All evaluated by periodontist samples saliva collected quantification S mutans. The received their first brushes appropriate instructions. For each leg, used period 30 days. At end washout period, participants periodontal...