Bente Kirkhus

ORCID: 0000-0003-2396-8906
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About
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Research Areas
  • Fatty Acid Research and Health
  • Diet and metabolism studies
  • Cholesterol and Lipid Metabolism
  • Meat and Animal Product Quality
  • Proteins in Food Systems
  • Protein Hydrolysis and Bioactive Peptides
  • Nutritional Studies and Diet
  • Cancer Cells and Metastasis
  • Reproductive Biology and Fertility
  • Food Chemistry and Fat Analysis
  • Diet, Metabolism, and Disease
  • Sperm and Testicular Function
  • Edible Oils Quality and Analysis
  • Lipid metabolism and biosynthesis
  • Beetle Biology and Toxicology Studies
  • Muscle metabolism and nutrition
  • Biochemical Analysis and Sensing Techniques
  • Carcinogens and Genotoxicity Assessment
  • Pluripotent Stem Cells Research
  • Food composition and properties
  • Infectious Diseases and Mycology
  • Lipoproteins and Cardiovascular Health
  • Consumer Attitudes and Food Labeling
  • Computational Drug Discovery Methods
  • Animal Genetics and Reproduction

Fafo Foundation
2009-2024

Nofima
2013-2024

Mills (Norway)
1998-2011

In-Q-Tel
2008

Norwegian University of Life Sciences
2006

Zero to Three
2001

General Mills (United States)
2001

Forskning.no (Norway)
1999

University of Oslo
1982-1992

Oslo University Hospital
1992

Developing a mechanistic understanding of the impact food structure and composition on human health has increasingly involved simulating digestion in upper gastrointestinal tract. These simulations have used wide range different conditions that often very little physiological relevance, this impedes meaningful comparison results. The standardized protocol presented here is based an international consensus developed by COST INFOGEST network. method designed to be with standard laboratory...

10.1038/s41596-018-0119-1 article EN cc-by Nature Protocols 2019-03-18

Abstract The purpose of the present study is to investigate effects krill oil and fish on serum lipids markers oxidative stress inflammation evaluate if different molecular forms, triacylglycerol phospholipids, omega‐3 polyunsaturated fatty acids (PUFAs) influence plasma level EPA DHA differently. One hundred thirteen subjects with normal or slightly elevated total blood cholesterol and/or triglyceride levels were randomized into three groups given either six capsules ( N = 36; 3.0 g/day, +...

10.1007/s11745-010-3490-4 article EN Lipids 2010-11-02

Understanding the mechanisms of food digestion is paramount importance to determine effect foods have on human health. Significant knowledge fate during has been generated in healthy adults due development physiologically-relevant vitro models. However, it appears that performance oro-gastrointestinal tract affected by ageing and a model simulating digestive conditions found younger adult (<65 years) not relevant for an older (>65 years). The objectives present paper were: (1) conduct...

10.1039/d3fo00535f article EN cc-by Food & Function 2023-01-01

Red meat high in heme iron may promote the formation of potentially genotoxic aldehydes during lipid peroxidation gastrointestinal tract. In this study, malondialdehyde (MDA) equivalents measured by thiobarbituric acid reactive substances (TBARS) method was determined vitro digestion cooked red (beef and pork), as well white (chicken) fish (salmon), whereas analysis 4-hydroxyhexenal (HHE) 4-hydroxynonenal (HNE) performed beef salmon. Comparing products with similar fat contents indicated...

10.1021/acs.jafc.5b04201 article EN Journal of Agricultural and Food Chemistry 2015-12-13

While the harmonized INFOGEST model provides a physiologically relevant platform for simulated digestion, it needs to be combined with adequate analytical methods enable quantification and comparison of protein digestibility in different food matrices. We have shown that size exclusion chromatography (SEC) can used estimate proportion small peptides potentially available uptake. Combined determination total dissolved protein, % per was calculated as (DSEC). Values DSEC differed casein...

10.1016/j.foodchem.2021.129830 article EN cc-by Food Chemistry 2021-04-20

The aim of the present study was to evaluate potential for production edible oil from organically grown camelina (Camelina sativa L. Crantz), focusing on influence environmental factors nutritional quality parameters. Field experiments with precrop barley were conducted in Norway growing seasons 2007, 2008, and 2009. Trials fully randomized two levels nitrogen (N) fertilization, 0 120 kg total N ha–1, sulfur (S) 20 S ha–1. Weather conditions, that is, temperature precipitation, recorded....

10.1021/jf304532u article EN Journal of Agricultural and Food Chemistry 2013-03-21

Nitrite derivatives react with endogenous precursors forming N-nitrosamines associated development of colorectal cancer. The present study aims to investigate the formation in sausage during processing and vitro gastrointestinal digestion after adding sodium nitrite and/or spinach emulsion. INFOGEST protocol was used simulate oral, gastric, small intestinal phases digestion, added oral phase mimic input from saliva as it has shown affect N-nitrosamines. results show that addition emulsion,...

10.1016/j.foodres.2023.112595 article EN cc-by Food Research International 2023-02-23

The aim of this study was to determine the extent which oat particle size in a porridge could alter glucose absorption, gastric emptying, gastrointestinal hormone response, and subjective feelings appetite satiety. Porridge prepared from either flakes or flour with same protein, fat, carbohydrate, mass. These were fed eight volunteers on separate days crossover study, ratings, contents, plasma glucose, insulin, hormones determined over period 3 h. flake gave lower response than porridge,...

10.1152/ajpgi.00005.2017 article EN AJP Gastrointestinal and Liver Physiology 2017-06-02

Nowadays, rapid freezing is sought to favor the formation of small ice crystals. Several studies have shown that application ultrasounds (US) accelerates processes energy and mass transfer when they are applied through immersion systems. However, there hardly any on its in direct systems without use a liquid medium for transmission. Therefore, objective this work was evaluate potential US improving process chicken breast samples. First, intermittent treatments at different net sonication...

10.1016/j.ultsonch.2020.105319 article EN cc-by-nc-nd Ultrasonics Sonochemistry 2020-08-28

Trans -fatty acids (TFA) have adverse effects on blood lipids, but whether TFA from different sources are associated with risk of CVD remains unresolved. The objective the present study was to evaluate association between intake partially hydrogenated vegetable oils (PHVO), fish (PHFO) and ruminant fat (rTFA) risks death CVD, CHD, cerebrovascular diseases sudden in Norwegian Counties Study, a population-based cohort study. Between 1974 1988, participants were examined for up three times. Fat...

10.1017/s0007114511005897 article EN British Journal Of Nutrition 2011-11-08

Intake of trans fatty acids (TFA) may influence systemic inflammation, insulin resistance and adiposity, but whether TFA intake influences cancer risk is insufficiently studied. We examined the association between from partially hydrogenated vegetable oils (PHVO-TFA), fish (PHFO-TFA), ruminant fat (rTFA) in Norwegian counties study, a large cohort study with participation rate >80%. was assessed three times 1974-1988 by questionnaire. A total 77,568 men women were followed up through 2007,...

10.1002/ijc.27737 article EN International Journal of Cancer 2012-07-23

Personalisation of foods opens for improving individuals' quality life. In the personalised food approach, focus research is food, its components and possibilities different processes throughout value chain to impact on individuals their needs. this paper, we will provide an overview how from a perspective can benefit consumers that require special offerings. The paper structured along addressing following topics: i) Food raw material components, ii) processing culinary aspects, iii)...

10.1016/j.tifs.2020.05.021 article EN cc-by Trends in Food Science & Technology 2020-06-16

Pulsed Electric Fields (PEF)-ohmic is one of the most recently proposed alternatives for application ohmic heating in order to provide a more uniform and faster food. In this study, PEF-ohmic (1.33 kV/cm, 100 Hz) blanching carrot cylinders was explored, inactivation peroxidase enzyme mathematically simulated experimentally validated. The effect treatment on texture its vitro bioaccessibility β-carotene were also determined. best uniformity achieved when applied carrots immersed water at...

10.1016/j.lwt.2023.115468 article EN cc-by-nc-nd LWT 2023-10-26

The aim of the present study was to examine effect a single high-fat meal with different fat quality on circulating inflammatory markers and gene expression in peripheral blood mononuclear cells (PBMC) elucidate role postprandial inflammation. A fourteen healthy females consuming three test meals performed. Test days were separated by 2 weeks. Fasting samples at 3 6 h after intake analysed. consisted cakes enriched coconut (43 % energy as saturated 1 α-linolenic acid (ALA)), linseed oil (14...

10.1017/s0007114511002510 article EN British Journal Of Nutrition 2011-06-07

Abstract We have compared the effects of three different margarines, one based on palm oil (PALM‐margarine), partially hydrogenated soybean ( TRANS ‐margarine) and with a high content polyunsaturated fatty acids (PUFA‐margarine), serum lipids in 27 young women. The main purpose study was to test if replacement trans margarine by palmitic acid results unfavorable lipids. sum saturated (12∶0, 14∶0, 16∶0) 36.3% total PALM‐diet, same as (12.5%) (23.1%) ‐diet. This 20.7% PUFA‐diet. oleic 37.9,...

10.1007/s11745-998-0284-9 article EN Lipids 1998-09-01

Summary. Sperm concentration, morphology, DNA condensation and nuclear protein pattern as well sperm adenylate cyclase were evaluated in semen samples provided by 7 volunteers every 8 h for 2 days. During the observation period, concentration total number decreased but began to return towards normal after a 3-day abstinence period. No increase proportion of immature cells was observed light microscopy. Total (EC 4.6.1.1) increased significantly per cell, due an soluble component while...

10.1530/jrf.0.0710135 article EN Reproduction 1984-05-01

We have compared the effects on lipoproteins and haemostatic variables of two hard margarines with similar functional properties, one traditional margarine containing partially hydrogenated fish oil (PHFO), experimental based vegetable (VO). Both were all-purpose cooking nearly identical properties. Trans fatty acids from PHFO in replaced mostly by saturated, monounsaturated trans origin new formulation. test contained approximately same amount cis polyunsaturated acids. Sixteen female...

10.1017/s0007114598001299 article EN British Journal Of Nutrition 1998-09-01

Epidermal basal cells from hairless mice were isolated after pulse labeling with tritiated DNA precursors and subjected to flow cytometry combined cell sorting. Cells sorted a window in the middle of S phase, collected on glass slides, autoradiography. Unlabeled phase found normal mouse epidermis optimal thymidine [( 3H]dThd), accordance previous results. The proportion unlabeled was considerably increased among treated growth-inhibitory epidermal extracts. Reanalysis re-sorting previously...

10.1111/1523-1747.ep12523189 article EN publisher-specific-oa Journal of Investigative Dermatology 1983-12-01
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