A5101955842- Liver Disease and Transplantation
- Liver Disease Diagnosis and Treatment
- Hepatocellular Carcinoma Treatment and Prognosis
- Organ Transplantation Techniques and Outcomes
- Inflammatory Bowel Disease
- Spectroscopy Techniques in Biomedical and Chemical Research
- Esophageal and GI Pathology
- GNSS positioning and interference
- Optical Polarization and Ellipsometry
- Advanced Measurement and Detection Methods
- Spectroscopy and Chemometric Analyses
- Gastrointestinal Bleeding Diagnosis and Treatment
- Diagnosis and treatment of tuberculosis
- Inflammatory mediators and NSAID effects
- Target Tracking and Data Fusion in Sensor Networks
- Glioma Diagnosis and Treatment
- Calibration and Measurement Techniques
- Mechanical stress and fatigue analysis
- Metabolism and Genetic Disorders
- Diet, Metabolism, and Disease
- Vibration and Dynamic Analysis
- Gastrointestinal disorders and treatments
- Mechanisms of cancer metastasis
- Gastric Cancer Management and Outcomes
- Electrical Contact Performance and Analysis
Zhujiang Hospital
2014-2025
Southern Medical University
2014-2025
Tianjin Research Institute of Electric Science (China)
2022
Second Affiliated Hospital of Xi'an Jiaotong University
2021
Jingzhou Central Hospital
2020
Yangtze University
2020
Children's Hospital of Zhejiang University
2017
Chinese People's Liberation Army
2015
Air Force Engineering University
2014
Children's Cancer Center
2014
Abstract Objective To evaluate the diagnostic accuracy and safety of using magnetically guided capsule endoscopy with a detachable string (ds-MCE) for detecting grading oesophagogastric varices in adults cirrhosis. Design Prospective multicentre study. Setting 14 medical centres China. Participants 607 (>18 years) cirrhosis recruited between 7 January 2021 25 August 2022. underwent ds-MCE (index test), followed by oesophagogastroduodenoscopy (OGD, reference test) within 48 hours. The...
Differentiation between Crohn's disease (CD) and intestinal tuberculosis (ITB) continues to be difficult. The present study investigated the collagen fibre characteristics of CD ITB using Masson's trichrome staining, second harmonic generation (SHG) imaging two-photon excited fluorescence (TPEF) with aim distinguishing them.The fibres in specimens from patients CD, healthy controls were compared staining SHG TPEF imaging.Masson's showed that content (540.92 [139.61-1681.93] vs 236.17...
Abstract Recently, the incidence of inflammatory bowel diseases, especially Crohn's disease (CD) and gastrointestinal luminal tuberculosis (ITB), has grown rapidly worldwide. Currently there is no general gold standard to distinguish between CD ITB tissues, which both have surrounding fibrous structures. Mueller matrix imaging technique suitable for describing location, density distribution behavior such In this study, we apply microscopic tissue samples. The 2D images slices are measured...
Abstract Background Graphene oxide (GO), a novel carbon-based nanomaterial, has promising applications in biomedicine. However, it induces potential cytotoxic effects on the gastrointestinal (GI) tract cells, and these have been largely uncharacterized. The present study aimed to explore toxic of GO intestinal especially under pre-existing inflammatory conditions, such as bowel disease (IBD), elucidate underlying mechanisms. Results Our findings indicated that oral gavage worsened acute...
The feasibility of early detection gastric cancer using near-infrared (NIR) Raman spectroscopy (RS) by distinguishing premalignant lesions (adenomatous polyp, n=27 ) and tissues (adenocarcinoma, n=33 from normal (n=45 is evaluated. Significant differences in spectra are observed among the normal, adenomatous adenocarcinoma at 936, 1003, 1032, 1174, 1208, 1323, 1335, 1450, 1655 cm −1 . Diverse statistical methods employed to develop effective diagnostic algorithms for classifying different...
Abstract Syndecan‐1 (Sdc1) and its endo‐beta‐ d ‐glucuronidase heparanase ( HPSE ) are implicated in maintenance of intestinal epithelial barrier IEB ), but their alterations roles high‐glucose/hyperglycaemia HG conditions have not been fully investigated. This study aimed to determine the expression pattern, possible regulation mechanism Sdc1 conditions, potential effects on . Therefore, diabetic mice/cell models were developed, tissue/serum samples, cell lysate culture supernatants...
Chronic atrophic gastritis (CAG) is a precancerous lesion and the first stage in multistep cascade that can lead to gastric adenocarcinoma. This study aimed reveal role mechanism of galangin CAG. Rats were intragastrically administered mixture 2% sodium salicylate 30% alcohol, forced exercise, fasted irregularly establish CAG models. To explore efficacy on rats, we used Hericium erinaceus (HE) omeprazole (Ome) as controls. The degree mucosal injury was assessed by H&E staining...
ABSTRACT Perfluoropentanone (C 5 F 10 O) gas mixtures are expected to be used in gas‐insulated switchgear due their excellent environmental and insulating properties. Nevertheless, the study of properties influencing factors C O under internal conditions is not yet comprehensive. This paper comprehensively investigates O/dry air mixtures. The findings demonstrate that adding significantly enhances mixture. this research serve as a valuable reference for engineering application, operation, maintenance
Abstract Background and Aim Gastroesophageal varices (GEV) present in compensated advanced chronic liver disease (cACLD) can develop into high‐risk (HRV). The gold standard for diagnosing GEV is esophagogastroduodenoscopy (EGD). However, EGD invasive less tolerant. This study aimed to validate radiomics signatures based on noncontrast‐enhanced computed tomography (CT) images non‐invasive diagnosis of HRV patients with cACLD. Methods multicenter trial enrolled 161 cACLD from six university...
Gastroesophageal varices is a serious complication of compensated advanced chronic liver disease (cACLD). Primary prophylaxis to reduce the risk variceal hemorrhage recommended if high-risk (HRV) are detected. We performed this study compare accuracy, patients' satisfaction and safety detection HRV by detachable string magnetically controlled capsule endoscopy (DS-MCCE) with esophagogastroduodenoscopy (EGD) as reference.We prospectively recruited participants cACLD from 12 university...
To evaluate the effects of hydrotalcite combined with esomeprazole on gastric ulcer healing quality.Forty-eight patients diagnosed between June 2014 and February 2016 were randomly allocated to combination therapy group or monotherapy group. The former received esomeprazole, latter alone, for 8 wk. Twenty-four healthy volunteers recruited acted as control Endoscopic was observed using white light endoscopy narrow band imaging magnifying endoscopy. composition collagen fibers, amount...
Liver targeting tags made up of gold nanostars and glycyrrhetinic acid were reported in this paper. Based on the tags, SERS signals corresponding matters early stage liver fibrosis analyzed. The diagnosis strategy might be a potential approach clinic.
Mueller matrix polarimetry is widely used in biomedical studies and applications, for it can provide abundant microstructural information about tissues. Recently, several methods have been proposed to decompose the into groups of parameters related specific optical properties which be reveal tissue samples more clearly quantitatively. In this study, we thoroughly compare differences among derived from polar decomposition (MMPD) transformation (MMT), are two popular while applying them on...
We have recently applied the technique of drop coating deposition Raman (DCDR) spectroscopy for colorectal cancer (CRC) detection using blood plasma. The aim this study was to develop a more convenient and stable method based on plasma noninvasive CRC detection. Significant differences are observed in DCDR spectra between healthy (n=105) (n=75) from 15 patients 21 volunteers, particularly that related proteins, nucleic acids, β-carotene. multivariate analysis principal components linear...
To screen fatty acid oxidation disorders (FAOD) in newborns Zhejiang province.A total of 1 861 262 were screened for FAOD Neonatal Screening Center Province during January 2009 and December 2016. The blood samples from by tandem mass spectrometry, diagnosis was confirmed urine organic measurement combined with genetic analysis. prognosis follow-up patients also evaluated.Of screened, 121 cases diagnosed. Among FAOD, primary carnitine deficiency (PCD) the most common type (n=78, 64.5%), which...
Hyponatremia is common in patients with decompensated cirrhosis and associated increased mortality. Tolvaptan, a vasopressor V2 receptor antagonist, can increase free water excretion, but its efficacy safety cirrhotic remain unclear. We studied the usage of tolvaptan real-life, non-randomized, multi-center prospective cohort study. Forty-nine hyponatremia were treated 15 mg daily, 48 not same period served as controls. Improvement serum sodium level was defined an from < 125 to ≥ mmol/L or...
Background Previous studies have highlighted changes in the cerebral cortical structure and cognitive function among nonalcoholic fatty liver disease (NAFLD) patients. However, impact of NAFLD on specific affected brain regions remains unclear. Therefore, we aimed to explore potential causal relationship between structure. Methods We conducted a Mendelian randomization (MR) study using genetic predictors alanine aminotransferase (ALT), NAFLD, percent fat (PLF) combined them with genome-wide...