A5086860197- Lung Cancer Treatments and Mutations
- Lung Cancer Research Studies
- Pancreatic and Hepatic Oncology Research
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Lung Cancer Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Pancreatitis Pathology and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Radiomics and Machine Learning in Medical Imaging
- Neuroendocrine Tumor Research Advances
- AI in cancer detection
- Dialysis and Renal Disease Management
- Gastrointestinal motility and disorders
- Gut microbiota and health
- Renal Diseases and Glomerulopathies
- Cancer Mechanisms and Therapy
- Surface Treatment and Coatings
- Cancer Immunotherapy and Biomarkers
- Blood Pressure and Hypertension Studies
- Chronic Kidney Disease and Diabetes
- Glutathione Transferases and Polymorphisms
- Metallic Glasses and Amorphous Alloys
- Chronic Lymphocytic Leukemia Research
- Gastrointestinal Bleeding Diagnosis and Treatment
Wuhan Asia Heart Hospital
2025
Wuhan University
2025
Hunan Cancer Hospital
2015-2024
Central South University
2004-2024
Shanghai Jiao Tong University
2019-2024
Ruijin Hospital
2019-2024
Yahoo (United Kingdom)
2024
Zunyi Medical University
2024
Nanjing University of Aeronautics and Astronautics
2012-2024
Hebei Medical University
2024
BackgroundAbelmoschus manihot, a single medicament of traditional Chinese medicine, has been widely used to treat kidney disease. This is the first randomized controlled clinical trial assess its efficacy and safety in patients with primary glomerular disease.Study DesignProspective, open-label, multicenter, randomized, controlled, trial.Setting & ParticipantsFrom May 2010 October 2011, total 417 biopsy-proven disease from 26 hospitals participated study.InterventionsA manihot form huangkui...
Abstract With a goal of improving operational numerical weather prediction (NWP), the Developmental Testbed Center (DTC) has been working with centers, including, among others, National Centers for Environmental Prediction (NCEP), Oceanic and Atmospheric Administration (NOAA), Aeronautics Space (NASA), U.S. Air Force, to support models/systems their research, perform objective testing evaluation NWP methods, facilitate research-to-operations transitions. This article introduces first attempt...
Abstract Objective To evaluate the diagnostic accuracy and safety of using magnetically guided capsule endoscopy with a detachable string (ds-MCE) for detecting grading oesophagogastric varices in adults cirrhosis. Design Prospective multicentre study. Setting 14 medical centres China. Participants 607 (>18 years) cirrhosis recruited between 7 January 2021 25 August 2022. underwent ds-MCE (index test), followed by oesophagogastroduodenoscopy (OGD, reference test) within 48 hours. The...
Background Growing evidence has shown that gut microbiome composition is associated with Biliary tract cancer (BTC), but the causality remains unknown. This study aimed to explore causal relationship between microbiota and BTC, conduct an appraisal of microbiome’s utility in facilitating early diagnosis BTC. Methods We acquired summary data for Genome-wide Association Studies (GWAS) pertaining BTC (418 cases 159,201 controls) from Biobank Japan (BBJ) database. Additionally, GWAS relevant (N...
Background A number of recent observational studies have indicated a correlation between the constitution gut microbiota and incidence pancreatitis. Notwithstanding, are unreliable for inferring causality because their susceptibility to confounding, bias, reverse causality, causal relationship specific pancreatitis is still unclear. Therefore, our study aimed investigate four types Methods An investigative undertaking encompassing genome-wide association (GWAS) comprising 18,340 participants...
Chronic pancreatitis (CP) is a progressive and irreversible fibroinflammatory disorder, accompanied by pancreatic exocrine insufficiency dysregulated gut microbiota. Recently, accumulating evidence has supported correlation between dysbiosis CP development. However, whether microbiota contributes to pathogenesis remains unclear. Herein, an experimental was induced repeated high-dose caerulein injections. The broad-spectrum antibiotics (ABX) ABX targeting Gram-positive (G+) or Gram-negative...
Abstract Background Studies have shown that integrating anlotinib with programmed death 1 (PD-1)/programmed death-ligand (PD-L1) inhibitors enhances survival rates among progressive non–small-cell lung cancer (NSCLC) patients lacking driver mutations. However, not all individuals experience clinical benefits from this therapy. As a result, it is critical to investigate the factors contribute inconsistent response of patients. Recent investigations emphasized importance lipid metabolic...
To realize the fault diagnosis of bearing effectively, this paper presents a novel method based on Gaussian restricted Boltzmann machine (Gaussian RBM). Vibration signals are firstly resampled to same equivalent speed. Subsequently, envelope spectrums data used directly as feature vectors represent types bearing. Finally, in order deal with high-dimensional spectrum, classifier model RBM is applied. has ability provide closed-form representation distribution underlying training data, and it...
Endoscopic ultrasonography-guided fine-needle aspiration/biopsy (EUS-FNA/B) is considered to be a first-line procedure for the pathological diagnosis of pancreatic cancer owing its high accuracy and low complication rate. The number new cases ductal adenocarcinoma (PDAC) increasing, accurate poses challenge cytopathologists. Our aim was develop hyperspectral imaging (HSI)-based convolution neural network (CNN) algorithm aid in EUS-FNA cytology specimens.
Background Data on the epidemiology of hypertension in Chinese non-dialysis chronic kidney disease (CKD) patients are limited. The aim present study was to investigate prevalence, awareness, treatment, and control CKD through a nationwide, multicenter China. Methods survey performed 61 tertiary hospitals 31 provinces, municipalities, autonomous regions China (except Hong Kong, Macao, Taiwan). Trained physicians collected demographic clinical data measured blood pressure (BP) using...
MET proto-oncogene amplification (amp) is an important mechanism underlying acquired resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). However, the optimal treatment strategy after acquiring MET-amp-mediated EGFR-TKI remains controversial. Our study compared three strategies for patients with EGFR-mutant non-small-cell lung cancer (NSCLC) who were detected MET-amp at progression using next-generation sequencing.Of 70 included in study, 38 received +...
Abstract Background The impact of neoadjuvant chemoimmunotherapy on pulmonary resection and related outcomes had been poorly reported in previous studies. present study aims to clarify the efficacy safety chemoimmunotherapy, intraoperative difficulty following surgery, comparison with chemotherapy alone non‐small cell lung cancer (NSCLC). Methods Patients newly diagnosed clinical stages IB–IIIB(T3‐4N2) NSCLC, received + PD‐1 inhibitors (PD‐1 Chemo group) or (Chemo followed by surgery between...
Spontaneous atrial dissection and aneurysm are extremely rare conditions. This may be the first reported case diagnosed in fetal period successfully treated with surgery under extracorporeal circulation infancy. Although infant this underwent successfully, recovered, was discharged, optimal timing for surgical intervention such cases remains unclear. report aims to provide a treatment reference similar cases.
Although the oral administration of Bifidobacterium longum (B. longum) relieves signs irritable bowel syndrome (IBS) in clinical settings, mechanisms underlying its effects are unclear. In this study, we evaluated precise B. on IBS via regulation Paneth cell function. We confirmed beneficial defecation habits and visceral hypersensitivity WAS rats. Further analysis revealed that enhanced mucosal repair, promoted lysozyme production, ameliorated dysbiosis microbiota These processes closely...
Endoscopic ultrasonography (EUS) is recommended as the best tool for evaluating gastric subepithelial lesions (SELs); nonetheless, it has difficulty distinguishing gastrointestinal stromal tumors (GISTs) from leiomyomas and schwannomas. GISTs have malignant potential, whereas schwannomas are considered benign.This study aimed to establish a combined radiomic model based on EUS images in stomach.EUS of pathologically confirmed GISTs, leiomyomas, were collected five centers. Gastric SELs...
Primary colorectal lymphoma (PCL) is an infrequently occurring form of cancer, with the elderly population exhibiting increasing prevalence disease. Furthermore, advanced age associated a poorer prognosis. Accurate prognostication essential for treatment individuals diagnosed PCL. However, no reliable predictive survival model exists patients Therefore, this study aimed to develop individualized prediction PCL and stratify its risk aid in monitoring patients. Patients aged 60 or older from...