- Pancreatic and Hepatic Oncology Research
- Gastric Cancer Management and Outcomes
- Pancreatitis Pathology and Treatment
- Gastrointestinal Tumor Research and Treatment
- Metastasis and carcinoma case studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Gastrointestinal disorders and treatments
- Esophageal and GI Pathology
- Helicobacter pylori-related gastroenterology studies
- Gallbladder and Bile Duct Disorders
- Liver Disease Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Intraperitoneal and Appendiceal Malignancies
- Neuroendocrine Tumor Research Advances
- Gastroesophageal reflux and treatments
- Radiomics and Machine Learning in Medical Imaging
- Renal cell carcinoma treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Ovarian cancer diagnosis and treatment
- Colorectal Cancer Screening and Detection
- Autophagy in Disease and Therapy
- Colorectal Cancer Surgical Treatments
- Lung Cancer Diagnosis and Treatment
- Vascular Anomalies and Treatments
- Foreign Body Medical Cases
Soochow University
2016-2025
Second Affiliated Hospital of Soochow University
2016-2025
Shanghai Jiao Tong University
2011-2013
Ruijin Hospital
2012
PLA Navy General Hospital
1992
BackgroundWe aimed to develop a deep learning-based segmentation system for rapid on-site cytopathology evaluation (ROSE) improve the diagnostic efficiency of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) biopsy.MethodsA retrospective, multicenter, study was conducted using 5345 cytopathological slide images from 194 patients who underwent EUS-FNA. These were Nanjing Drum Tower Hospital (109 patients), Wuxi People's (30 Second (25 and The Affiliated Soochow University...
Summary Aims Thioredoxin‐interacting protein ( TXNIP ) is associated with activation of oxidative stress through inhibition thioredoxin (Trx). However, some evidences point out that acts as a scaffolding in signaling complex independent cellular redox regulation. The autophagy‐lysosomal pathway plays important roles the clearance misfolded proteins and dysfunctional organelles. Lysosomal dysfunction has been involved several neurodegenerative disorders including Parkinson's disease PD )....
Objectives The objective of this study was to investigate the effects rat umbilical cord mesenchymal stem cells (UCMSCs) from Wharton's jelly on dibutyltin dichloride (DBTC)–induced chronic pancreatitis (CP) and subsequent pancreatic fibrosis in rats. Methods A model CP induced by DBTC used. Male Sprague-Dawley rats were randomly divided into 4 groups: control, DBTC, + UCMSCs, control UCMSC groups. Umbilical administered intravenously day 5 after administration DBTC. On days 14 28, evaluated...
Endoscopic ultrasonography (EUS) is recommended as the best tool for evaluating gastric subepithelial lesions (SELs); nonetheless, it has difficulty distinguishing gastrointestinal stromal tumors (GISTs) from leiomyomas and schwannomas. GISTs have malignant potential, whereas schwannomas are considered benign.This study aimed to establish a combined radiomic model based on EUS images in stomach.EUS of pathologically confirmed GISTs, leiomyomas, were collected five centers. Gastric SELs...
Introduction both percutaneous transhepatic cholangiography and drainage (PTCD) endoscopic retrograde cholangiopancreatography (ERCP) with SEMS implantation have been used for unresectable hilar cholangiocarcinoma (HC) in the clinic many years. However, which one is preferred still unknown. Objective to study effects of biliary self-expanding metal stents (SEMS) under PTCD or ERCP treat HC. Methods clinical data 82 patients HC from January 2006 2015 were recorded retrospectively. Patients...
Linked colour imaging (LCI) is a novel new image-enhanced endoscopy (IEE) technology that produces bright and vivid images. The aim of this study was to assess the ability LCI improve diagnostic accuracy early gastric cancer (EGC) relative white light (WLI).
INTRODUCTION: Endoscopic transmural drainage (TMD) has been accepted as the preferred therapy for symptomatic pancreatic fluid collections (PFCs). Recurrence of PFCs presents a unique challenge in patients with disrupted duct (PD). We aimed to evaluate whether transpapillary (TPD) provides additional benefits TMD PD disruption. METHODS: This was multicenter retrospective study. Consecutive who underwent TMD, TPD, or combined (CD) were included. The primary outcome compare PFC recurrence...
The diagnosis of peritoneal carcinomatosis accompanied by ascites is challenging, particularly when the primary site remains unidentified. While cytological examination commonly advocated, diagnostic sensitivity approximately 60% [1]. remaining 40% patients may require more invasive procedures, such as laparoscopy or laparotomy. In recent years, endoscopic ultrasound (EUS) has extended its reach to carcinomatosis, offering enhanced visualization and a minimally approach [2] [3]. case...
Background and study aims There is a high prevalence of Helicobacter pylori infection. White light endoscopy (WLE) can be used for evaluating the mucosal lesions, but it does not have diagnostic efficiency. Linked color imaging (LCI) newly developed endoscopic technique. The aim this was to compare LCI with WLE in detecting staging H. infection stomach randomized controlled clinical trial. Patients methods A total 253 patients who had indications gastroduodenoscopy were enrolled into Group...
BACKGROUNDAdenomyomatous hyperplasia of the distal common bile duct (CBD) is very rare, with only scarce case reports in literature.Diagnosis usually based on imaging findings, and endoscopic biopsy difficult before operation.It believed that adenomyomatous has little or no risk malignant transformation. CASE SUMMARYA 68-year-old woman abdominal pain right upper quadrant was referred to our hospital.Abdominal ultrasonography emergency ward revealed acute cholecystitis dilated CBD.Laboratory...
Goals: To comprehensively compare the wet suction technique with conventional dry for endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in solid lesions. Background: Optimal techniques EUS-FNA remain uncertain when approaching Study: We performed a retrospective study of at 3 medical centers China. A total 203 patients were enrolled who received 2 passes 22-G needles. If first pass underwent suction, second was suction. Otherwise, order is opposite. Diagnostic accuracy, sample...
A 31-year-old woman was admitted into the endocrinology department of our hospital presenting with nausea and vomiting for 1 day on 17 January 2016. She had a medical history diabetes (type 1) 10 years, recurrent diabetic ketoacidosis in past several gastroparesis year. When hospitalized 7 days treatment metoclopramide, insulin, vitamin B12 etc. were not relieved. On 25 2016, guided by linear endoscopic ultrasound (EUS, EG-530UT, FUJIFILM SU 8000; Fujifilm Corporation, Tokyo, Japan), we...
Abstract Procalcitonin (PCT) is widely used to diagnose a bacterial infection. An increased serum PCT can also be observed in tumors. We presented an unusual case of metastatic PNET producing and secreting PCT. Immunohistochemistry was demonstrate that secreted by PanNET.